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HNRNPC belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). 再加上，我们可以发Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) 抗体 (124) 和 Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) 试剂盒 (15)和数多这个蛋白质的别的产品。
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APP levels then decrease progressively as a function of age in close relationship with the gradual normalization of FMRP and hnRNP C levels.
Endoplasmic reticulum resident chaperone GRP78 (显示 HSPA5 蛋白), mitochondrial protein (显示 COX6B2 蛋白) Prohibitin (显示 PHB 蛋白) and heterogeneous nuclear ribonucleoprotein (显示 PCBP2 蛋白) hnRNPC (C1/C2) have been shown to interact with viral RNA. Hence it is proposed that these are the principle candidates governing endoplasmic reticulum stress-induced apoptosis in JEV infection.
Our results indicate that a balance between lncRNA SNHG1 and hnRNPC regulates p53 (显示 TP53 蛋白) activity and p53 (显示 TP53 蛋白)-dependent apoptosis upon doxorubicin treatment, and further indicate that a change in lncRNA subcellular localization under specific circumstances is biologically significant.
These data suggest an interplay between CELF2 (显示 CELF2 蛋白) and hnRNP C as the mechanistic basis for activation-dependent alternative splicing of TRAF3 (显示 TRAF3 蛋白) exon 8.
These findings suggest that hnRNP C1/C2 is involved in dengue virus replication at the stage of viral RNA synthesis.
HnRNP C, YB-1 (显示 YBX1 蛋白) and hnRNP L (显示 HNRNPL 蛋白) coordinately enhance skipping of human MUSK (显示 MUSK 蛋白) exon 10 to generate a Wnt (显示 WNT2 蛋白)-insensitive MuSK (显示 MUSK 蛋白) isoform.
Our results suggested that hnRNP C1 controls HPV16 late gene expression.
m(6)A-switch-regulated HNRNPC-binding activities affect the abundance as well as alternative splicing of target mRNAs, demonstrating the regulatory role of m(6)A-switches on gene expression and RNA maturation
PTBP1 (显示 PTBP1 蛋白) and hnRNP C repress exon 3 inclusion, and that downregulation of PTBP1 (显示 PTBP1 蛋白) inhibited BIM (显示 BCL2L11 蛋白)-mediated apoptosis.
down-regulation of MALAT-1 expression compromised the cytoplasmic translocation of hnRNP C in the G2/M phase and resulted in G2/M arrest
hnRNP C and hnRNP H (显示 HNRNPH2 蛋白) bind to the 3'-UTR of the circadian clock gene Period 2 (mPer2 (显示 PER2 蛋白)).
Neither hnRNP-C nor FMRP (显示 FMR1 蛋白) is required for cyclic AMP (显示 TMPRSS5 蛋白) to stimulate APP (显示 APP 蛋白) and Amyloid beta production.
our results reveal a new function of the splicing factor (显示 SLU7 蛋白) hnRNP C in the maturation of dendritic cells that involves regulating the expression of NF-kappaB (显示 NFKB1 蛋白) p65 (显示 NFkBP65 蛋白) and its downstream targets CD80 (显示 CD80 蛋白) and CD40 (显示 CD40 蛋白).
CK1alpha-mediated phosphorylation modulates the mRNA binding ability of hnRNP-C
Data suggest that increased levels of hnRNP C1/C2 may modulate XIAP (显示 XIAP 蛋白) translation by interacting with the XIAP (显示 XIAP 蛋白)-IRES, and may foster synthesis of XIAP (显示 XIAP 蛋白) as a protective pathway by which neurons try to counteract the initial deleterious effects of apoptosis.
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.
heterogeneous nuclear ribonucleoproteins C1/C2
, hnRNP C1/C2
, nuclear ribonucleoprotein particle C1 protein
, nuclear ribonucleoprotein particle C2 protein
, heterogeneous nuclear ribonucleoprotein C (C1/C2)
, heterogeneous nuclear ribonucleoprotein C1
, heterogeneous nuclear ribonucleoprotein C2
, heterogeneous ribonucleoprotein C1/C2
, hnRNP C1 / hnRNP C2
, hnRNP C2
, snoRNA MBI-122
, heterogeneous nuclear ribonucleoprotein C
, hnRNP C protein C-terminal fragment (158 AA)
, hnRNP core protein C
, hnRNP C
, C protein