Hepatocyte Growth Factor Activator 蛋白 (HGFA)

The protein encoded by HGFA belongs to peptidase family S1. 再加上,我们可以发Hepatocyte Growth Factor Activator 抗体 (53)Hepatocyte Growth Factor Activator 试剂盒 (15)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
HGFA 54426 Q9R098
HGFA 58947  
HGFA 3083 Q04756
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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大肠杆菌(E. Coli) 小鼠 His tag,GST tag 100 μg Log in to see 15至18个工作日
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大肠杆菌(E. Coli) 大鼠 His tag,GST tag 100 μg Log in to see 15至18个工作日
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人细胞 His tag 20 μg Log in to see 14至16个工作日
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大肠杆菌(E. Coli) 非结合性   100 μg Log in to see 11至18个工作日
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HGFA 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine) ,
,
Rat (Rattus)

Human , ,

更多Hepatocyte Growth Factor Activator (HGFA)互动伙伴

Mouse (Murine) Hepatocyte Growth Factor Activator (HGFA) interaction partners

  1. HNF1alpha might regulate beta-cell mass or function at least partly by modulating Hgfac expression.

  2. HGFA is required for repair of injured intestinal mucosa but is not essential for normal development during embryogenesis or after birth.

Human Hepatocyte Growth Factor Activator (HGFA) interaction partners

  1. Based upon ethnicity-stratified single-variant association analysis and trans-ethnic meta-analysis of 6201 participants of the Multi-Ethnic Study of Atherosclerosis, discovered 5 common and low-frequency variants: HGF missense polymorphism rs5745687 (p.E299K) and 4 variants (rs16844364, rs4690098, rs114303452, rs3748034) within or in proximity to HGFAC.[Meta-analysis]

  2. the HGF-activator has a role in multiple myeloma cells' catalysis of hepatocyte growth factor (HGF) activation

  3. HGF/MET signaling and aberrant HGF-activator expression is associated with diffuse large B-cell lymphoma

  4. KLK4 and KLK5 activate pro-HGFA.

  5. Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c-Met system via hypoxia inducible factor-1 in pancreatic cancer.

  6. the activated form of HGFA is present at high levels in serum and bone marrow of myeloma patients, thus providing a necessary prerequisite for the activation of HGF.

  7. Results suggest that hepatocyte growth factor activator is a major serum activator of pro-macrophage-stimulating protein.

  8. HAI-1 (serine peptidase inhibitor, Kunitz type 1) specifically traps active form of HGF activator on cellular surface and regulates HGF activation in pericellular microenvironment.

蛋白简介Hepatocyte Growth Factor Activator (HGFA)

蛋白简介

The protein encoded by this gene belongs to peptidase family S1. It is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form.

Gene names and symbols associated with HGFA

  • HGF activator (HGFAC)
  • hepatocyte growth factor a (hgfa)
  • hepatocyte growth factor activator (LOC100303670)
  • hepatocyte growth factor activator (Hgfac)
  • HGF activator (Hgfac)
  • HGFA 蛋白

Protein level used designations for HGFA

HGF activator , hepatocyte growth factor activator , hepatocyte growth factor , Hepatocyte growth factor activator

GENE ID SPECIES
422876 Gallus gallus
750533 Pan troglodytes
100139648 Bos taurus
100195110 Salmo salar
100303670 Meleagris gallopavo
54426 Mus musculus
58947 Rattus norvegicus
3083 Homo sapiens
403432 Canis lupus familiaris
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