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The protein encoded by HGFA belongs to peptidase family S1. 再加上，我们可以发Hepatocyte Growth Factor Activator 抗体 (53) 和 Hepatocyte Growth Factor Activator 试剂盒 (14)和数多这个蛋白质的别的产品。
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HNF1alpha might regulate beta-cell mass or function at least partly by modulating Hgfac expression.
HGFA is required for repair of injured intestinal mucosa but is not essential for normal development during embryogenesis or after birth.
Based upon ethnicity-stratified single-variant association analysis and trans-ethnic meta-analysis of 6201 participants of the Multi-Ethnic Study of Atherosclerosis, discovered 5 common and low-frequency variants: HGF missense polymorphism rs5745687 (p.E299K) and 4 variants (rs16844364, rs4690098, rs114303452, rs3748034) within or in proximity to HGFAC.[Meta-analysis]
the HGF-activator has a role in multiple myeloma cells' catalysis of hepatocyte growth factor (HGF) activation
HGF/MET signaling and aberrant HGF-activator expression is associated with diffuse large B-cell lymphoma
KLK4 and KLK5 activate pro-HGFA.
Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c-Met system via hypoxia inducible factor-1 in pancreatic cancer.
the activated form of HGFA is present at high levels in serum and bone marrow of myeloma patients, thus providing a necessary prerequisite for the activation of HGF.
Results suggest that hepatocyte growth factor activator is a major serum activator of pro-macrophage-stimulating protein.
HAI-1 (serine peptidase inhibitor, Kunitz type 1) specifically traps active form of HGF activator on cellular surface and regulates HGF activation in pericellular microenvironment.
The protein encoded by this gene belongs to peptidase family S1. It is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form.
, hepatocyte growth factor activator
, hepatocyte growth factor
, Hepatocyte growth factor activator