anti-Hemoglobin, delta (HBd) 抗体

The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. 再加上,我们可以发HBd 蛋白 (17)HBd 试剂盒 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HBd 3045 P02042
HBd    
HBd    
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Showing 10 out of 17 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 ELISA, IHC (p), WB Western blot analysis of HBD using anti-HBD antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: human placenta tissue lysates, Lane 2: rat spleen tissue lysates, Lane 3: mouse spleen tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-HBD antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for HBD at approximately 16KD. The expected band size for HBD is at 16KD. Western blot analysis of HBD using anti-HBD antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: human placenta tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-HBD antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for HBD at approximately 16KD. The expected band size for HBD is at 16KD. 100 μg Log in to see 4至6个工作日
$280.00
详细
非结合性 ICC, IHC, WB Figure. Western Blot; Sample: Recombinant HBd, Human. Figure. DAB staining on IHC-P; Samples: Human Liver Tissue. 100 μg Log in to see 15至18个工作日
$350.00
详细
非结合性 IF/ICC, IHC, IP, WB Western blot analysis of recombinant Human HBd. IHC-P analysis of Human Liver Tissue, with DAB staining. 100 μg Log in to see 11至18个工作日
$440.62
详细
小鼠 非结合性 WB   50 μL Log in to see 11至13个工作日
$308.12
详细
非结合性 ELISA, IHC, WB   100 μg Log in to see 13至16个工作日
$407.69
详细
FITC ELISA   100 μg Log in to see 11至16个工作日
$412.19
详细
HRP ELISA   100 μg Log in to see 11至16个工作日
$412.19
详细
Biotin ELISA   100 μg Log in to see 11至16个工作日
$412.19
详细
非结合性 ELISA, IHC   100 μg Log in to see 11至16个工作日
$412.19
详细
大鼠 非结合性 WB   100 μL Log in to see 11至16个工作日
$412.19
详细

更多抗HBd的相互作用对抗体

Human Hemoglobin, delta (HBd) interaction partners

  1. Blood donor homozygous for Hb D Los Angeles.

  2. The expression of the activated delta-globin gene in a beta-thalassemia mice model greatly improves the phenotype, validating the delta-globin chain as a therapeutic target for beta-hemoglobinopathies.

  3. Data indicate that a delta-globin mutation was suspected in both patients.

  4. Twenty-one different mutations were detected, and of these 12 have not been previously described.

  5. A functional promoter polymorphism of the delta-globin gene is a specific marker of the Arab-Indian haplotype

  6. This report describes a novel missense mutation in delta-globin (HBD: c.323G>A, Gly > Asp) in an Indian family with heterozygous beta-thalassemia with normal HbA(2) levels.

  7. Family study reporting normal Hemoglobin A expression in a beta-goblin carrier (beta(+) IVSI-5 (G to C) mutation) with microcytosis and hypochromiadue, due to co-inheritance of mutation in the delta-globin gene (delta codon 12 (AAT-->AAA) HbA2-NYU).

  8. Studies present five new hemoglobin (Hb) variants, Hb Canuts, Hb Ambroise Pare, Hb Beaujolais, Hb Monplaisir and Hb(A2)-North Africa.

  9. Data report the study of 23 double heterozygotes for beta- and delta-thalassemia defects or variants. Eight delta-globin and seven beta-globin alleles were detected. All the alleles were associated with RFLP haplotype background.

  10. The 5' breakapoint of the (deltabeta)(0) thalassemia deletion in a compound heterozygote was located in the second intron of the delta globin gene.

  11. Hb A2-Monreale [delta146(HC3)His-->Arg]is a novel delta chain variant.

  12. alternate mRNA species in adult erythroid cells; mRNA encodes an additional 145 nt in the upstream untranslated region, suggesting an alternative site of transcriptional initiation and transcription through the previously defined promoter

  13. The atomic coordinates of the delta-chain of hemoglobin A2 (R2 state) are used to model the structure of hemoglobin homotetramer delta 4, which occurs in rare hemoglobin H disease.

  14. Deletion pf this geneis a common, and possibly the predominant beta-thalassemia mutation of the Austroasiatic Lao Theung population.

  15. characterization of the delta-globin gene alleles and of RFLP-haplotypes, SNPs and one microsatellite associated with them in 231 carriers originating principally from East Sicily; Seventeen alleles were identified, of which five were new

  16. Borderline HbA(2) is not a rare event in a population with a high prevalence of beta-thalassemia carriers

  17. Unusually low levels of HBA2 in a compound heterozygote can be explained from the functional inhibition of the HBD gene, in cis to the HBG1 gene, bearing the nd-HPFH mutation.

  18. Hb A2 IVS-I-5 (G > C) beta-thalassemia mutation phenotype in 289 carriers was reported.

HBd 抗原简介

蛋白简介

The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia.

Gene names and symbols associated with anti-Hemoglobin, delta (HBd) 抗体

  • hemoglobin subunit delta (HBD) 抗体
  • hemoglobin subunit delta (hbd) 抗体
  • hemoglobin subunit beta (LOC476825) 抗体
  • hemoglobin, delta (HBD) 抗体
  • hemoglobin subunit delta S homeolog (hbd.S) 抗体
  • hbb 抗体
  • MGC89723 抗体

Protein level used designations for anti-Hemoglobin, delta (HBd) 抗体

Hemoglobin delta chain , Hemoglobin subunit delta , delta-globin , hemoglobin, beta , delta globin , delta-globin chain , hemoglobin delta chain , hemoglobin subunit delta , hemoglobin, delta , beta-1-globin , globin, beta I, larval , hemoglobin beta-1 chain, larval , hemoglobin larval subunit beta-1

GENE ID SPECIES
748577 Pan troglodytes
3045 Homo sapiens
448665 Xenopus (Silurana) tropicalis
476825 Canis lupus familiaris
100137311 Papio anubis
379431 Xenopus laevis
100439260 Pongo abelii
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