anti-Hemoglobin, alpha 2 (HBa2) 抗体

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. 再加上,我们可以发HBa2 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HBa2 3040 P69905
HBa2 360504 P01946
HBa2    
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Showing 10 out of 26 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 ELISA, ICC, IF, WB Western blot analysis of HBA2 using Jurkat whole  lysates. ABIN6278025 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL 11至12个工作日
$390.77
详细
非结合性 FACS, IHC (p), WB Overlay histogram showing K562 cells stained with Antibody (green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (1:25 dilution) for 60 min at 37ºC. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight 488 Conjugated Highly Cross-Adsorbed(OH191631) at 1/200 dilution for 40 min at 37ºC. Isotype control antibody (blue line) was rabbit IgG (1ug/1x10^6 cells) used under the same conditions. Acquisition of >10, 000 events was performed. Western Blot at 1:2000 dilution + human fetal heart lysate Lysates/proteins at 20 ug per lane. 400 μL 2至3个工作日
$515.63
详细
小鼠 非结合性 WB Western blot analysis of extracts of mouse liver cells, using HBA2 antibody. Immunohistochemistry of paraffin-embedded mouse heart using HBA2 antibody at dilution of 1:100 (x40 lens). 100 μL 11至13个工作日
$366.77
详细
小鼠 非结合性 IHC, WB Western blot analysis of extracts of mouse liver, using HBA2 antibody. Immunohistochemistry of paraffin-embedded mouse heart using HBA2 antibody. 200 μL 12至14个工作日
$438.90
详细
非结合性 FACS, IHC, ELISA, WB   200 μL 11至16个工作日
$658.43
详细
非结合性 FACS, IHC, WB 200 μL 11至16个工作日
$596.97
详细
APC FACS, IHC, ELISA, WB   200 μL 16 Days
$814.00
详细
FITC FACS, IHC, ELISA, WB   200 μL 16 Days
$814.00
详细
HRP IHC, ELISA, WB   200 μL 16 Days
$814.00
详细
PE FACS, IHC, ELISA, WB   200 μL 16 Days
$814.00
详细

更多抗HBa2的相互作用对抗体

Human Hemoglobin, alpha 2 (HBa2) interaction partners

  1. Despite the structural similarity of myoglobin to alpha and beta subunits of hemoglobin, there is a functional difference between the two proteins, owing to the quaternary structure of hemoglobin. The effect of the quaternary structure of hemoglobin on the intrinsic dynamics of its subunits is explored by dynamical comparison of the two proteins.

  2. Prx2 interacts with hemoglobin A (Alpha2Beta2) and hemoglobin F (Alpha2Gamma2) but not with hemoglobin A2 (Alpha2Delta2)

  3. genetic factors other than beta-thal can rarely contribute to the elevation of Hb A2. These subjects usually have borderline microcytic red cell indices and Hb A2 values.

  4. Coinherited HBD mutation lowers Hb A2 and can cause a misidentification of a beta-thalassemia carrier.

  5. Chinese family with delta-thalassemia (delta-thal) was found, in which the daughter is homozygous for delta-thal (HBD: c.-127T>C) with complete deficiency of Hb A2 and the mother is a heterozygote with low level of Hb A2

  6. father carried the rare nondeletional Hb Adana mutation [alpha59(E8)Gly-->Asp, HBA2: c.179G>A] on the alpha2-globin gene

  7. Changes in HbA2 and HbF in alpha thalassemia carriers with KLF1 mutation.

  8. A single genetic origin is responsible for the spread and high prevalence of the alpha(0)-thalassemia (SEA deletion) in Southeast Asian populations and allow the monitoring of possible maternal contamination at prenatal diagnosis of this important genetic disorder.

  9. In this study, a novel promoter mutation of -72 (T-->A) within the conserved CCAAT box of beta-globin gene has been identified in heterozygous state. The proband and his two relatives carrying the same mutation showed almost normal mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) level and slightly elevated HbA2.

  10. In this paper, the experimental results of resonance Raman, terahertz time-domain, and 1H nuclear magnetic resonance spectroscopy for the Hb M are described in detail. The heterogeneity of alpha subunits, which has been observed previously, is reconfirmed, and its implications for the dynamical structure of the alpha2beta2 tetramer and the regulation of O2 affinity are discussed.

  11. This study presents comparison of two neutron structures of hemoglobins, human deoxyhemoglobin (T state) and equine cyanomethemoglobin (R state) and offers a direct observation of histidine residues that are likely to contribute to the Bohr effect.

  12. Carriers of Hb Nanning are asymptomatic and could be missed by screening based on MCV and MCH cutoffs of <80.0 fL and <27.0 pg, respectively. Both carriers of the mutation in the study have MCV and MCH values that are 2 standard deviations (SDs) below normal, as would be predicted for an alpha+-thal.

  13. Data indicate that binding of hemoblobin (Hb) to glycoprotein1balpha (GP1balpha) induced platelet activation plays a crucial role in thrombus formation on immobilized von Willebrand factor (VWF) or type I collagen under shear stresses.

  14. Hb Adana mutation was preferentially present in the alpha2-globin genes in Malays compared to the other ethnicities in Malaysia.

  15. 14 alpha thalassemia mutations were found among 95 Turkish patients. Most were gene deletions. A new alpha 2 initiation codon mutation was discovered.

  16. The hematological and molecular data of 35 patients with Hb H disease and the genotypes of alpha-gene mutations of 78 screened individuals were used to identify the genotypes of Hb H disease and genotype-phenotype correlations. the most common genotypes were -alpha3.7/--20.5, -alpha3.7/--26.5, and -alpha3.7/--17.5. Other small deletions, non-deleltional mutations, and combinations thereof in trans were associated with...

  17. Seven novel nondeletional alpha-thalassemia mutations localized on the alpha2-globin gene in the heterozygous state were identified

  18. Gene frequency for HBA2:c.301-24delGinsCTCGGCCC carriers among the Chinese population in Guangxi.

  19. Hemoglobin Constant Spring mutation in Southeast Asians with thalassemia.

  20. We report herein for the first time the description of HbA2' in the Tunisian population.

Cow (Bovine) Hemoglobin, alpha 2 (HBa2) interaction partners

  1. both Ciprofloxacin and enrofloxacin could lead to the conformational and microenvironmental changes of bovine hemoglobin.

  2. Determination of a representative formal redox potentials of the Fe(II)/Fe(III) redox couple cyanhaemoglobin/cyanmethaemoglobin and the myoglobin/metmyoglobin , at pH=7 and related to the state in solution, was the objective of this work.

  3. Data indicate that on incubating hemoglobin with glyoxal for 0-20 days, advanced glycation end products (AGEs) were detected on day 20.

  4. Ultraviolet irradiation results in fluorescence enhancement of bovine hemoblobin in a dose-dependent manner.

  5. These results indicate that IsdX2 has all the features required to acquire heme from the host and transport heme to the bacterial cell wall.

  6. Residues 33-61a of hemoglobin alpha-chain from cattle tick gut exhibit nonconventional conformation for an antimicrobial peptide, bound to sodium dodecyl sulfate micelles. The peptide is able to disrupt the bacterial membrane of Micrococcus luteus A270.

  7. The acid-induced denaturation of Hb follows a highly symmetric mechanism.

Horse (Equine) Hemoglobin, alpha 2 (HBa2) interaction partners

  1. This study presents comparison of two neutron structures of hemoglobins, human deoxyhemoglobin (T state) and equine cyanomethemoglobin (R state) and offers a direct observation of histidine residues that are likely to contribute to the Bohr effect.

  2. cyanomethemoglobin is in the R state and preliminary room-temperature electron and neutron scattering density maps clearly show the protonation states of potential Bohr groups.

HBa2 抗原简介

蛋白简介

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin\; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1\; some nondeletion alpha thalassemias have also been reported.

Gene names and symbols associated with anti-Hemoglobin, alpha 2 (HBa2) 抗体

  • hemoglobin subunit alpha 2 (HBA2) 抗体
  • hemoglobin subunit alpha 2 L homeolog (hba2.L) 抗体
  • hemoglobin subunit mu (HBM) 抗体
  • hemoglobin, alpha 2 (HBA) 抗体
  • hemoglobin, alpha 2 (HBA2) 抗体
  • hemoglobin, alpha 2 (Hba2) 抗体
  • alpha globin 抗体
  • HBA2 抗体
  • hba5 抗体
  • HBH 抗体

Protein level used designations for anti-Hemoglobin, alpha 2 (HBa2) 抗体

alpha globin , alpha-2 globin , alpha-globin , hemoglobin alpha chain , hemoglobin subunit alpha , alpha T5 (aa 1-142) , alpha-5-globin , alpha-T5 , hemoglobin alpha-5 chain , hemoglobin subunit alpha-5 , adult alpha D globin , hemoglobin alpha-D chain , hemoglobin subunit alpha-D , hemoglobin, alpha 2 , globin, alpha 2 , hemoglobin, subunit alpha 2 , 2-alpha globin , 2-alpha-1 globin , hemoglobin alpha 2 chain

GENE ID SPECIES
3040 Homo sapiens
379435 Xenopus laevis
416651 Gallus gallus
512439 Bos taurus
100036558 Equus caballus
360504 Rattus norvegicus
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