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Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. 再加上，我们可以发HSP90AA2 蛋白 (6)和数多这个蛋白质的别的产品。
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Human Polyclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN266969
Peterson, Moran, Conley, Bird: Zonal expression of endothelial nitric oxide synthase in sheep and rhesus adrenal cortex. in Endocrinology 2001
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Human Monoclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN361663
Arlander, Eapen, Vroman, McDonald, Toft, Karnitz: Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress. in The Journal of biological chemistry 2003
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Human Polyclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN4320479
Bzowska, Nogieć, Bania, Zygmunt, Zarębski, Dobrucki, Guzik: Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages. in Journal of leukocyte biology 2017
Human Polyclonal HSP90AA2 Primary Antibody for IF (p), IHC (p) - ABIN1714199
Ding, Wu, Su, Zhou, Zhao, Deng, Zhang, Liu, Wang, Liu: Expression of heat shock protein 90 genes during early development and infection in Megalobrama amblycephala and evidence for adaptive evolution in teleost. in Developmental and comparative immunology 2013
Knocking out Hsp90beta (显示 HSP90AB1 抗体) leads to tumour cell death. Extracellular supplementation with recombinant Hsp90alpha, but not Hsp90beta (显示 HSP90AB1 抗体), protein recovers tumourigenicity of the Hsp90alpha-knockout cells. Sequential mutagenesis identifies two evolutionarily conserved lysine residues, lys (显示 LYZ 抗体)-270 and lys (显示 LYZ 抗体)-277, in the Hsp90alpha subfamily that determine the extracellular Hsp90alpha function.
We revealed that Hsp90A (显示 HSP90AA1 抗体) and Hsp90B (显示 HSP90AB1 抗体) are partly colocalized with heparan sulfate proteoglycans (HSPGs) on the cell surface and that this colocalization was sensitive to heparin.
Heat shock protein 90 stimulates rat mesenchymal stem cell migration via PI3K/Akt and ERK1/2 pathways
Studied the serum prolactin (显示 PRL 抗体), cortisol, and ACTH (显示 POMC 抗体) stress response of intensive care unit (ICU) patients with severe sepsis/septic shock (SS) or systemic inflammatory response syndrome (SIRS) compared to healthy subjects.
These results indicate that cytoplasmic HSP90alpha may serve as a biomarker for perineural invasion in pancreatic cancer
Increased expression of nucleated RBC (显示 CACNA1C 抗体), HSP90alpha and corresponding decreased expression of HO-2 (显示 HMOX2 抗体) in such hypoxic condition may play a protective role; to prevent cord blood RBC (显示 CACNA1C 抗体) against stress induced damage during preeclampsia.
STAT5b (显示 STAT5B 抗体) pathway regulates Hsp90alpha expression under hypoxic conditions
HSP90alpha was an IMH-2 epitope-associated protein. Tumor HSP90alpha overexpression was correlated with the metastasis and poor prognosis of colorectal cancer patients.
extracellular HSP90alpha transactivates EGFR/ErbB1 (显示 EGFR 抗体) through TLR4 (显示 TLR4 抗体) and a PKCdelta (显示 PKCd 抗体)/c-Src (显示 SRC 抗体) pathway, which induces ATP release and cytosolic Ca(2 (显示 CA2 抗体)+) increase and finally favors glioblastoma cell migration.
High gene expression of Hsp90 alpha (显示 HSP90AA1 抗体) is associated with leukemia.
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Plays a key role in slow and fast muscle development in the embryo. Plays a role in myosin expression and assembly.