anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2) 抗体

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. 再加上,我们可以发HSP90AA2 蛋白 (7)和数多这个蛋白质的别的产品。

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HSP90AA2 3324
HSP90AA2  
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antibodies-online.cn销售最多的anti-HSP90AA2 抗体

Showing 10 out of 212 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 ICC, IF, IHC (p), IP, IHC, WB Figure 1 shows a Western blot of mouse HSP84 and HSP86 using ABIN266969 and ABIN266968, respectively. Western Blot: HSP90 alpha Antibody [ABIN266969] - Proteins were transferred to a PVDF membrane and blocked with 5% BSA/TBST for at least 1 hour. The membrane was probed with a HSP86 polyclonal antibody at a dilution of 1:1000 overnight at 4C on a rocking platform, washed in TBS-0.1%Tween 20, and probed with a goat anti-rabbit IgG HRP secondary antibody at a dilution of 1:20,000 for at least 1 hour. 0.1 mg Log in to see 7至9个工作日
$488.73
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小鼠 非结合性 ICC, IF, IP, IHC, ELISA, WB Western Blotting Hsp90lpha RatTissue 10ug 1 in 1000 copy. 50 μg Log in to see 3至4个工作日
$257.40
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小鸡 非结合性 IC, IF, IHC, WB Immunofluorescent analysis of HSP90 alpha staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of HSP90 alpha staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13至14个工作日
$487.50
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非结合性 ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: HSP90 alpha Antibody (SY14-06)  - Staining Hsp90 alpha in Ags cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. Immunocytochemistry/Immunofluorescence: HSP90 alpha Antibody (SY14-06)  - Staining Hsp90 alpha in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 100 μL Log in to see 34 Days
$375.73
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小鼠 非结合性 CyTOF, ELISA, FACS, IHC, IHC (p), WB Immunohistochemistry-Paraffin: HSP90 alpha Antibody (5G5) [NBP2-22208] - Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using Hsp90A mouse mAb with DAB staining. Flow Cytometry: HSP90 alpha Antibody (5G5) [NBP2-22208] - Flow cytometric analysis of HeLa cells using Hsp90A mouse mAb (green) and negative control (red). 0.1 mL Log in to see 7至9个工作日
$516.98
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小鼠 HRP IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Log in to see 3至4个工作日
$517.40
详细
小鼠 FITC IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Log in to see 3至4个工作日
$522.60
详细
小鼠 Alkaline Phosphatase (AP) IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Log in to see 3至4个工作日
$525.20
详细
小鼠 Biotin IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Log in to see 3至4个工作日
$527.80
详细
小鼠 PE IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Log in to see 3至4个工作日
$529.10
详细

引用最多的anti-HSP90AA2 抗体

  1. Human Polyclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN266969 : Peterson, Moran, Conley, Bird: Zonal expression of endothelial nitric oxide synthase in sheep and rhesus adrenal cortex. in Endocrinology 2001 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN361663 : Arlander, Eapen, Vroman, McDonald, Toft, Karnitz: Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress. in The Journal of biological chemistry 2003 (PubMed)
    Show all 15 Pubmed References

  3. Human Polyclonal HSP90AA2 Primary Antibody for IF (p), IHC (p) - ABIN1714199 : Ding, Wu, Su, Zhou, Zhao, Deng, Zhang, Liu, Wang, Liu: Expression of heat shock protein 90 genes during early development and infection in Megalobrama amblycephala and evidence for adaptive evolution in teleost. in Developmental and comparative immunology 2013 (PubMed)

  4. Human Polyclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN4320479 : Bzowska, Nogieć, Bania, Zygmunt, Zarębski, Dobrucki, Guzik: Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages. in Journal of leukocyte biology 2017 (PubMed)

更多抗HSP90AA2的相互作用对抗体

Human Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2) interaction partners

  1. Study suggests that HSP90AA2 gene polymorphisms are associated with SLE susceptibility in Chinese population.

  2. The Hsp90alpha binds human recombinant p23 about three times stronger than Hsp90beta but with significantly smaller exothermic enthalpy as determined by isothermal titration calorimetry of direct binding between the purified proteins.

  3. Knocking out Hsp90beta leads to tumour cell death. Extracellular supplementation with recombinant Hsp90alpha, but not Hsp90beta, protein recovers tumourigenicity of the Hsp90alpha-knockout cells. Sequential mutagenesis identifies two evolutionarily conserved lysine residues, lys-270 and lys-277, in the Hsp90alpha subfamily that determine the extracellular Hsp90alpha function.

  4. We revealed that Hsp90A and Hsp90B are partly colocalized with heparan sulfate proteoglycans (HSPGs) on the cell surface and that this colocalization was sensitive to heparin.

  5. Heat shock protein 90 stimulates rat mesenchymal stem cell migration via PI3K/Akt and ERK1/2 pathways

  6. Studied the serum prolactin, cortisol, and ACTH stress response of intensive care unit (ICU) patients with severe sepsis/septic shock (SS) or systemic inflammatory response syndrome (SIRS) compared to healthy subjects.

  7. These results indicate that cytoplasmic HSP90alpha may serve as a biomarker for perineural invasion in pancreatic cancer

  8. Increased expression of nucleated RBC, HSP90alpha and corresponding decreased expression of HO-2 in such hypoxic condition may play a protective role; to prevent cord blood RBC against stress induced damage during preeclampsia.

  9. Heat shock protein 90alpha is a substrate and chaperone of DNA-PK necessary for the apoptotic response.

  10. STAT5b pathway regulates Hsp90alpha expression under hypoxic conditions

  11. HSP90alpha was an IMH-2 epitope-associated protein. Tumor HSP90alpha overexpression was correlated with the metastasis and poor prognosis of colorectal cancer patients.

  12. extracellular HSP90alpha transactivates EGFR/ErbB1 through TLR4 and a PKCdelta/c-Src pathway, which induces ATP release and cytosolic Ca(2+) increase and finally favors glioblastoma cell migration.

  13. High gene expression of Hsp90 alpha is associated with leukemia.

  14. extracellular Hsp90alpha promotes angiogenesis in an MMP-2-dependent manner.

  15. that Hsp90alpha can be secreted by activated endothelial cells and is a positive regulator of angiogenesis, suggesting the potential application of Hsp90alpha as a stimulator for wound repair.

  16. Promoter activity analysis revealed that hepatitis B virus X protein is directly involved in the c-Myc-mediated transcriptional activation of HSP90alpha.

  17. The hsp90 alpha isoform, but not hsp90 beta, is expressed extracellularly where it interacts with the matrix metalloproteinase 2 (MMP2). Inhibition of extracellular hsp90 alpha decreases both MMP2 activity and invasiveness.

  18. The reciprocal interactions of HSP90 and NF-kappa B activities are likely to constitute a regulatory loop, able to influence cell survival and response to stressful agents

  19. These findings provide a rationale for targeting HSP90alpha protein as a therapeutic candidate for glioma.

  20. C-terminal tail and determinants in the alphaE-helix of the catalytic domain allows the chaperones Hsp90 and Cdc37 to bind newly synthesized PKC beta II, a required event in the processing of PKC by phosphorylation

HSP90AA2 抗原简介

蛋白简介

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Plays a key role in slow and fast muscle development in the embryo. Plays a role in myosin expression and assembly.

Gene names and symbols associated with HSP90AA2

  • heat shock protein 90 alpha family class A member 2, pseudogene (HSP90AA2P) 抗体
  • HSP90ALPHA 抗体
  • HSPCA 抗体
  • HSPCAL3 抗体
GENE ID SPECIES
3324 Homo sapiens
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