Use your antibodies-online credentials, if available.
Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance.
Showing 10 out of 90 products:
Human GDF15 ELISA Kit for Sandwich ELISA - ABIN624984
Barderas, Mendes, Torres, Bartolomé, López-Lucendo, Villar-Vázquez, Peláez-García, Fuente, Bonilla, Casal: In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion. in Molecular & cellular proteomics : MCP 2013
Show all 9 Pubmed References
Human GDF15 ELISA Kit for Sandwich ELISA - ABIN415137
Sun, Huang, Phillips, Luo, Zhu, Shi, Li: Growth differentiation factor 15 and coronary collateral formation. in Clinical cardiology 2010
Human GDF15 ELISA Kit for Sandwich ELISA - ABIN365728
Jiang, Yu, Wang, Tang, Guo, Jiao: Regulation of hepcidin through GDF-15 in cancer-related anemia. in Clinica chimica acta; international journal of clinical chemistry 2014
GDF15 was significantly correlated with mitochondrial disease severity and the proportion of ragged (显示 SOX18 ELISA试剂盒)-red fibers identified in skeletal muscle.
GDF-15 serum levels were elevated in patients with Systemic sclerosis and correlated with the extent of skin fibrosis, and it was found to be higher in Systemic sclerosis patients with interstitial pulmonary fibrosis
Enhanced radiosensitivity and decreased migration in cells caused by CDP138 knockdown are partially dependent on GDF15 inhibition.
these results suggest that increased GDF-15-as observed in lungs of smokers and patients with COPD (显示 ARCN1 ELISA试剂盒)-contributes to cigarette smoke-induced pulmonary inflammation.
High GDF15 levels are associated with increased risk of major amputation and/or death in peripheral arterial disease patients.
we found that GDF-15 -3148C/G polymorphism (CC genotype) might have a correlation with acute ST-elevation myocardial infarction occurrence and the formation of collateral circulation.
Data show that serum growth differentiation factor 15 (GDF15)levels were significantly higher in subjects with thyroid nodules compared with nodule negative subjects, and this was influenced by age.
Findings suggest that GDF15 induces tumor sphere formation through GDF15-ERK1/2 (显示 MAPK1/3 ELISA试剂盒)-GDF15 circuits, leading to maintenance of GDF15high cancer stem-like cells.
These authors demonstrate that blocking cardiomyocyte production of GDF15 normalizes circulating GDF15 level and restores liver growth hormone (显示 GH1 ELISA试剂盒) signaling, establishing GDF15 as a bona fide heart-derived hormone that regulates pediatric body growth.
Authors demonstrated that GDF15 contributed to radioresistance of HNC (显示 MMP8 ELISA试剂盒), as determined by both gain- and lost-of-functional experiments. Authors further showed that GDF15 facilitated the conversion of cancer stemness, as assessed by the promotion of CD44 (显示 CD44 ELISA试剂盒)+ and ALDH1 (显示 ALDH1A1 ELISA试剂盒)+ cell populations and spheroid cell formation.
Membrane-protein extraction and use of an intracellular protein-transport inhibitor showed that GDF-15 promoted CaV3.1 and CaV3.3 alpha-subunit (显示 POLG ELISA试剂盒) expression by trafficking to the membrane.
CHOP (显示 DDIT3 ELISA试剂盒) activates Gdf15 transcription via binding to its promoter upon endoplasmic reticulum stress.
The ANT1 (显示 SLC25A4 ELISA试剂盒)-deficient muscle mitochondria produce excess reactive oxygen species (ROS (显示 ROS1 ELISA试剂盒)) and are partially uncoupled. Hence, the muscle respiration under nonphosphorylating conditions is increased. Muscle transcriptome analysis revealed the induction of mitochondrial biogenesis, down-regulation of diabetes-related genes, and increased expression of the genes encoding the myokines FGF21 (显示 FGF21 ELISA试剂盒) and GDF15.
isolating GFRAL as the receptor for GDF15-induced anorexia and weight loss, the identification of a mechanistic basis for the non-homeostatic regulation of neural circuitry by a peripheral signal associated with tissue damage and stress; findings provide opportunities to develop therapeutic agents for the treatment of disorders with altered energy demand
These data suggest that GDF15 is required for IL-13 (显示 IL13 ELISA试剂盒)-induced improvement of glucose intolerance in mice fed an HFD.
HIF-1alpha (显示 HIF1A ELISA试剂盒) and GDF15 expression are inversely related under normoxia and hyperoxia.
This is the first study defining the role of Mic-1/Gdf15 in a number of behavioural domains.
epithelial restitution was promoted by enhanced NAG-1 expression and subsequent enterocyte locomotion during the early wound-healing process
both GDF-15 and TGF-beta1 (显示 TGFB1 ELISA试剂盒) counteract chemokine (显示 CCL1 ELISA试剂盒)-induced integrin activation on neutrophils via the ALK-5 (显示 TGFBR1 ELISA试剂盒)/TGF-betaRII heterodimer.
GDF15 is a potent mitohormetic signal that safeguards against the onset of obesity and insulin (显示 INS ELISA试剂盒) resistance.
Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.
growth differentiation factor 15
, NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1
, NSAID-activated gene 1 protein
, NSAID-regulated gene 1 protein
, growth/differentiation factor 15
, macrophage inhibitory cytokine 1
, placental TGF-beta
, placental bone morphogenetic protein
, prostate differentiation factor
, macrophage inhibiting cytokine-1