anti-Golgi Reassembly Stacking Protein 1, 65kDa (GORASP1) 抗体

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. 再加上,我们可以发Golgi Reassembly Stacking Protein 1, 65kDa 蛋白 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
GORASP1 74498 Q91X51
GORASP1 56082  
GORASP1 64689 Q9BQQ3
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Showing 10 out of 55 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-GORASP1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Hela cell lysate GORASP1 is supported by BioGPS gene expression data to be expressed in HeLa 100 μL Log in to see 2至3个工作日
$289.00
详细
小鼠 非结合性 FACS, IF, IHC, IHC (p), WB 100 μL Log in to see 11至14个工作日
$507.83
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非结合性 ICC, IF, IHC, IHC (p) Immunohistochemistry: GRASP65 Antibody [NBP2-47443] - Analysis of human salivary gland shows strong cytoplasmic positivity(dot-like pattern) in glandular cells. Immunocytochemistry/Immunofluorescence: GRASP65 Antibody [NBP2-47443] - Analysis of human cell line HeLa shows positivity in the Golgi apparatus. 0.1 mL Log in to see 10至13个工作日
$494.38
详细
小鼠 非结合性 IF, WB 100 μL Log in to see 11至14个工作日
$507.83
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Cow 非结合性 WB 50 μg Log in to see 11至14个工作日
$551.83
详细
非结合性 ELISA, IHC, WB Western blot analysis GORASP1 using Jurkat whole cell lysates Western blot analysis of extracts from mouse brain, using GORASP1 Antibody. 100 μL Log in to see 11至12个工作日
$390.77
详细
Cow 非结合性 IHC, IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 50 μg Log in to see 11至14个工作日
$727.83
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非结合性 WB GORASP1 Antibody (Center)  western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the GORASP1 antibody detected the GORASP1 protein (arrow). 400 μL Log in to see 10至11个工作日
$385.00
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非结合性 WB Western blot analysis in MCF-7 cell line lysates (35ug/lane). 400 μL Log in to see 2至3个工作日
$515.63
详细
小鼠 非结合性 FACS, ICC, IF, IHC, IHC (p), WB Western Blot: GRASP65 Antibody (5G8) [NBP2-02665] Analysis of extracts (35ug) from 9 different cell lines by using anti-GRASP65 monoclonal antibody. Immunocytochemistry/Immunofluorescence: GRASP65 Antibody (5G8) [NBP2-02665] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY GRASP65. 0.1 mL Log in to see 8至11个工作日
$559.35
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更多抗Golgi Reassembly Stacking Protein 1, 65kDa的相互作用对抗体

Human Golgi Reassembly Stacking Protein 1, 65kDa (GORASP1) interaction partners

  1. In situ proximity ligation assays of Golgi localization of alpha-mannosidase IA at giantin versus GM130-GRASP65 site, and absence or presence of N-glycans terminated with alpha3-mannose on trans-Golgi glycosyltransferases may be useful for distinguishing indolent from aggressive prostate cancer cells.

  2. Results demonstrate a critical role for GRASP55 and GRASP65 in maintaining the stacked structure of the Golgi, which is required for accurate posttranslational modifications in the Golgi. Additionally, the GRASP knockout cell lines developed in this study will be useful tools for studying the role of GRASP proteins in other important cellular processes.

  3. The authors determined that Golgi membrane ribbon fragmentation increased during the early cytoplasmic phase of cytomegalovirus virion assembly and that Golgi membrane fragmentation in infected cells was dependent on the phosphorylation of an integral cis-Golgi protein, Grasp65.

  4. In cells, Mena and actin were required for Golgi ribbon formation after nocodazole washout; in vitro, Mena and microfilaments enhanced GRASP65 oligomerization and Golgi membrane fusion. Thus Mena interacts with GRASP65 to promote local actin polymerization, which facilitates Golgi ribbon linking.

  5. Mutagenesis experiments support these structural observations and demonstrate that they are required for GRASP65-GM130 association.

  6. Cisternal-specific functions of GRASP65 and GRASP55 in continuity, compartmentalization, and function of the Golgi ribbon.

  7. propose that GRASP55/65 are negative regulators of exocytic transport and that this slowdown helps to ensure more complete protein glycosylation in the Golgi stack and proper sorting at the trans-Golgi network

  8. The C-terminal fragments of GRASP65 produced following caspase cleavage are targeted to mitochondria, and ectopic expression of these sensitises HeLa cells to Fas ligand.

  9. the mechanism of phosphoinhibition as direct inhibition by PLK1 of the PDZ ligand underlying the GRASP65 self-interaction.

  10. GRASP65 has a role in Golgi cisternal stacking and cell cycle progression

  11. These results demonstrate that GRASP55 and GRASP65 stack mammalian Golgi cisternae via a common mechanism.

  12. Data demonstrate that both GRASP55 and 65 are needed for the efficient transport to and through the Golgi complex, thus highlighting a novel role for the GRASPs in membrane trafficking.

  13. the GRASP domain alone of GRASP65 inhibits mitotic fragmentation of the Golgi apparatus

  14. GRASP65 may function as a signal integrator controlling the cell growth

  15. GRASP65 has a role in the regulation of spindle dynamics rather than a direct role in the stacking of Golgi cisternae

  16. Ribbon formation requires the Golgi proteins GM130 and GRASP65.

  17. Mitochondria bearing GRASP65 became tethered to one another, and this depended on a GRASP65 PDZ domain that was also required for GRASP65 self-interaction.

  18. A study showing that GRASP65 binds directly to the coiled-coil vesicle tethering factor GM130, and targets it to Golgi membranes.

  19. Identification of GRASP65, and demonstration that it functions in the formation of stacked Golgi cisternae.

Golgi Reassembly Stacking Protein 1, 65kDa (GORASP1) 抗原简介

蛋白简介

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Several alternatively spliced transcript variants of this gene have been identified, but their full-length natures have not been determined.

Gene names and symbols associated with GORASP1

  • golgi reassembly stacking protein 1 (GORASP1) 抗体
  • golgi reassembly stacking protein 1 (gorasp1) 抗体
  • golgi reassembly stacking protein 1 (PTRG_03298) 抗体
  • golgi perepheral membrane protein p65 (PY00200) 抗体
  • golgi reassembly stacking protein 1 (Gorasp1) 抗体
  • golgi reassembly stacking protein 1a (gorasp1a) 抗体
  • 5430411C10Rik 抗体
  • cb744 抗体
  • GOLPH5 抗体
  • GRASP65 抗体
  • MGC69226 抗体
  • MGC134531 抗体
  • P65 抗体
  • zgc:101588 抗体

Protein level used designations for GORASP1

Golgi reassembly-stacking protein 1 , golgi reassembly stacking protein 1, 65kDa , golgi reassembly stacking protein 1 , golgi reassembly-stacking protein 1-like , Golgi reassembly-stacking protein 1-like , golgi perepheral membrane protein p65 , golgi peripheral membrane protein p65 , golgi reassembly-stacking protein of 65 kDa , Golgi peripheral membrane protein p65 , Golgi phosphoprotein 5 , Golgi reassembly and stacking protein 1

GENE ID SPECIES
420426 Gallus gallus
448042 Xenopus (Silurana) tropicalis
613757 Bos taurus
694728 Macaca mulatta
747594 Pan troglodytes
6341527 Pyrenophora tritici-repentis Pt-1C-BFP
100454646 Pongo abelii
100518933 Sus scrofa
100602572 Nomascus leucogenys
3807146 Plasmodium yoelii yoelii 17XNL
74498 Mus musculus
56082 Rattus norvegicus
64689 Homo sapiens
485594 Canis lupus familiaris
492770 Danio rerio
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