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Transfer of galactose from UDP-galactose to an acceptor molecule (R). 再加上，我们可以发GGTA1 蛋白 (2)和数多这个蛋白质的别的产品。
The results suggest that in alpha1,3-GalT (显示 GALT ELISA试剂盒) the substrate-assisted catalysis would be necessary in both mechanisms, because the nucleophilic strength of Glu317 is reduced by the interactions it makes to ensure proper acceptor binding.
Many waitlisted renal transplant patients have minimal xenoreactive antibody binding to the GGTA1/CMAH/B4GalNT2 (显示 B4GALNT2 ELISA试剂盒) knockout pig, but some HLA antibodies in sensitized patients cross-react with class I SLA (显示 SLA ELISA试剂盒).
Silencing the porcine CMAH/GGTA1 genes necessary to avoid antibody-mediated rejection in a pig-to-human model also reduces the xenogeneic consumption of human platelets by the porcine liver.
alpha 1-3-N-acetylgalactosaminyltransferase (显示 B4GALNT2 ELISA试剂盒)-knockout pig did not appear to have an advantage over the GalT (显示 GALT ELISA试剂盒)-KO pig with respect to reactivity with human antibodies from a xenotransplantation perspective
GGTA1/CMAH knockout pig samples had increased relative amounts of high-mannose, incomplete, and xylosylated N-linked glycans
study demonstrated that ZFN is an efficient tool in creating gene-modified pigs. GGTA1 null pigs and GGTA1 null fetal fibroblasts would benefit research and pig-to-human transplantation
Anti-gal (显示 GAL ELISA试剂盒) antibodies in alpha1,3-galactosyltransferase gene-knockout pigs.
Human CD55 (显示 CD55 ELISA试剂盒) expression blocks hyperacute rejection and restricts complement activation in Gal (显示 GAL ELISA试剂盒) knockout cardiac xenografts.
These multidisciplinary results suggest that genetic modification to eliminate the alphaGal epitopes in the extracellular matrix (ECM (显示 MMRN1 ELISA试剂盒)) bioscaffolds had not altered the properties of these ECM (显示 MMRN1 ELISA试剂盒) bioscaffolds.
transgenic male pigs were produced that possess an alpha alpha-1,3-galactosyltransferase knockout allele and express a randomly inserted human alpha 1,2-fucosylosyltransferase transgene
Higher antibody binding and cytotoxicity to wild type cells compared with alpha1,3-galactosyltransferase gene-knockout cells show greater cytotoxicity to antibodies.
Transfer of galactose from UDP-galactose to an acceptor molecule (R).
ABO-family member protein 5
, N-acetyllactosaminide alpha-1,3-galactosyltransferase
, UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase
, glycosyltransferase 6 domain-containing protein 1
, alpha Gal
, glycoprotein alpha galactosyl transferase 1