Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) ELISA试剂盒

GATM encodes a mitochondrial enzyme that belongs to the amidinotransferase family. 再加上,我们可以发GATM 抗体 (89)GATM 蛋白 (12)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
GATM 2628 P50440
GATM 67092 Q9D964
GATM 81660 P50442
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Human Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) interaction partners

  1. Measurements of creatine and guanidinoacetate in plasma are recommended for the diagnosis of AGAT and GAMT (显示 GAMT ELISA试剂盒) deficiency.Definitive confirmation of the diagnosis requires DNA sequencing of the appropriate gene and (if molecular analysis is ambiguous) measurement of AGAT or GAMT (显示 GAMT ELISA试剂盒) enzyme activity or of CRTR (显示 SLC6A8 ELISA试剂盒)-mediated transport .

  2. Results show the functional characterization of rare missense variants in GATM which cause GATM deficiency. Seven of them report 0% of wild-type GATM activity indicating a putative pathogenicity.

  3. Data suggest that creatine is provided equally by diet and by endogenous synthesis from arginine and glycine with successive involvement of arginine glycine amidinotransferase [AGAT] and guanidinoacetate methyl transferase [GAMT (显示 GAMT ELISA试剂盒)]. [REVIEW]

  4. AGAT deficiency is a treatable intellectual disability.

  5. Meta-analysis yielded a marginal, but null, association of GATM rs9806699 with statin-induced myopathy.

  6. Genome-wide association reveals that plasma homoarginine is strongly associated with single nucleotide polymorphisms in the AGAT gene.

  7. promiscuous activity of AGAT, a key enzyme in creatine synthesis, plays a pivotal role in homoarginine synthesis

  8. GATM sequencing revealed a homozygous single nucleotide insertion 1111_1112insA, producing a frame-shift at Met-371 and premature termination at codon 376.

  9. AGAT mRNA expression was significantly elevated in all heart failure patients and returned to normal levels after recovery, suggesting a specific response to heart failure involving elevated local creatine synthesis.

Pig (Porcine) Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) interaction partners

  1. For the GATM BseLI polymorphism, the Yorkshire and Duroc breeds have higher allele frequencies at the G allele, whereas the local pigs have higher allele frequencies at the A allele. (GATM; glycine amidinotransferase)

Mouse (Murine) Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) interaction partners

  1. results show marked metabolic effects of creatine deficiency via the chronic activation of AMPK (显示 PRKAA1 ELISA试剂盒) in a first animal model of AGAT deficiency

Zebrafish Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) interaction partners

  1. The spatiotemporal expression pattern of gatm during zebrafish embryogenesis was revealed.

GATM 抗原简介

Antigen Summary

This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.

Gene names and symbols associated with GATM

  • glycine amidinotransferase (L-arginine:glycine amidinotransferase) L homeolog (gatm.L) 抗体
  • glycine amidinotransferase (GATM) 抗体
  • glycine amidinotransferase (L-arginine:glycine amidinotransferase) (Gatm) 抗体
  • glycine amidinotransferase (Gatm) 抗体
  • glycine amidinotransferase (L-arginine:glycine amidinotransferase) (gatm) 抗体
  • 1810003P21Rik 抗体
  • AGAT 抗体
  • AI314789 抗体
  • AT 抗体
  • cb409 抗体
  • CCDS3 抗体
  • wu:fa08a06 抗体
  • zgc:65855 抗体

Protein level used designations for GATM

L-arginine:glycine amidinotransferase , Transamidinase , glycine amidinotransferase, mitochondrial , arginine:glycine amidinotransferase , transamidinase , AT , L-arginine: glycine amidinotransferase , l-arginine:glycine amidinotransferase , agat

GENE ID SPECIES
379386 Xenopus laevis
395504 Gallus gallus
2628 Homo sapiens
414733 Canis lupus familiaris
100126844 Sus scrofa
414732 Bos taurus
67092 Mus musculus
81660 Rattus norvegicus
266799 Danio rerio
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