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GSTZ1 is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. 再加上，我们可以发Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) 抗体 (58) 和 Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) 试剂盒 (6)和数多这个蛋白质的别的产品。
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mild hypersuccinylacetonaemia (MHSA)can be caused by sequence variants in GSTZ1. Such individuals have thus far remained asymptomatic despite receiving no specific treatment.
We conclude that the lower expression of GSTZ1 in Whites who possess the K carrier haplotype results in lower enzymatic activity and slower metabolism of DCA, compared with those who possess the non-K carrier haplotype
Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children
The data indicates no association between GSTZ1 genotypes and risk of gastric cancer.
Two SNPs, rs282070 located in intron 1 of the MAP3K7 (显示 MAP3K7 蛋白) gene, and rs2111699 located in intron 1 of the GSTZ1 gene, were significantly associated (after adjustment for multiple testing) with longevity in stage 2
The ping-pong catalytic mechanism of Se-hGSTZ1-1 is similar to that of the natural GPX (显示 GPX1 蛋白).
Elucidation of the role of individual residues in the N-terminal, SSC (显示 CYP11A1 蛋白) motif of human GSTZ1.
This study was performed on 228 BPD patients and 234 control subjects. Among early-onset patients, the variant alleles of Glu32Lys and G-1002A increased BPD susceptibility.
e report for the first time the conversion of human glutathione transferase Zeta (hGSTZ1-1) into seleno-hGSTZ1-1 by means of genetic engineering in eukaryotes.
The present results indicate that the haplotype of "-1002A, 32Lys, 42Arg" (containing three variant alleles) of GSTZ1 have protective effect compared to the other haplotypes.
Maleylacetoacetate isomerase (MAAI/GSTZ)-deficient mice reveal a glutathione-dependent nonenzymatic bypass in tyrosine catabolism
GSTZ1-1 deficiency may alter the metabolism of some drugs and xenobiotics.
glutathione S-transferase (显示 GSTa2 蛋白) zeta/maleylacetoacetate isomerase is induced by C/EBPalpha (显示 CEBPA 蛋白) and dependent on PPAR gamma (显示 PPARG 蛋白)
This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.
, glutathione S-alkyltransferase
, glutathione S-aralkyltransferase
, glutathione S-aryltransferase
, glutathione transferase zeta 1
, maleylacetoacetate isomerase
, maleylacetone isomerase
, glutathione transferase zeta 1 (maleylacetoacetate isomerase)
, glutathione S-transferase zeta 1
, glutathione S-transferase alpha 3
, glutathione S transferase Z1
, glutathione S-transferase zeta 1 L homeolog