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GAD65 蛋白

(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008].
GAD65 Protein (AA 1-585) (GST tag) GAD65 Protein (AA 1-585) (GST tag) GAD65 Protein (AA 1-585) (GST tag) (ABIN1354671)

GAD2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

GAD65 蛋白 GAD65 蛋白 GAD65 蛋白 (ABIN7195934)

GAD2 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE

GAD65 Protein (GST tag,His tag) GAD65 Protein (GST tag,His tag) GAD65 Protein (GST tag,His tag) (ABIN7320201)

GAD2 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 92 % as determined by SDS-PAGE

GAD65 蛋白 by Grade

Find GAD65 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

GAD65 蛋白 by Origin

Find GAD65 蛋白 for a variety of species such as anti-Human GAD65, anti-Mouse GAD65, anti-Rat GAD65. The species listed below are among those available. Click on a link to go to the corresponding products.

GAD65 蛋白 by Source

Here you will find GAD65 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

GAD65 蛋白 by 蛋白类型

Here you can find GAD65 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

GAD65 蛋白 by 应用范围

Find GAD65 蛋白 validated for a specific application such as WB, SDS, PC, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular GAD65 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1354671
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7195934
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7320201
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7317017
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3078697
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3134189
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401977
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401158
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393595
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5709545
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2721539
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2721540
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1170550
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2750058
Quantity 5 applications
Datasheet Datasheet
Reactivity Arabidopsis thaliana
Source Yeast
Validations
Cat. No. ABIN1628623
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GAD65 蛋白

Grupillo, Gualtierotti, He, Sisino, Bottino, Rudert, Trucco, Fan: "Essential roles of insulin expression in Aire+ tolerogenic dendritic cells in maintaining peripheral self-tolerance of islet ?-cells." in: Cellular immunology, Vol. 273, Issue 2, pp. 115-23, (2012) (PubMed).

Fan, Rudert, Grupillo, He, Sisino, Trucco: "Thymus-specific deletion of insulin induces autoimmune diabetes." in: The EMBO journal, Vol. 28, Issue 18, pp. 2812-24, (2009) (PubMed).

Aliases for GAD65 蛋白

glutamate decarboxylase 2 (GAD2) 蛋白
glutamate decarboxylase 2 (PTRG_06148) 蛋白
glutamate decarboxylase 2 (LOC9324534) 蛋白
glutamate decarboxylase 2 (Gad2) 蛋白
glutamate decarboxylase 1 (GAD1) 蛋白
glutamate decarboxylase 2 (gad2) 蛋白
glutamic acid decarboxylase 2 (Gad2) 蛋白
6330404F12Rik 蛋白
F12P19.12 蛋白
F12P19_12 蛋白
GAD(65) 蛋白
Gad-2 蛋白
GAD65 蛋白
gad65 蛋白
GLUTAMATE DECARBOXYLASE 2 蛋白
glutamate decarboxylase 2 蛋白
zgc:112198 蛋白
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