anti-Gasdermin D (GSDMD) 抗体

Gasdermin D is a member of the gasdermin family. 再加上,我们可以发Gasdermin D 试剂盒 (13)Gasdermin D 蛋白 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
GSDMD 79792 P57764
GSDMD 69146 Q9D8T2
GSDMD 315084  
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antibodies-online.cn销售最多的anti-Gasdermin D 抗体

Showing 10 out of 32 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: GSDMDC1 Antibody [NBP2-33422] - Ovarian cancer Immunohistochemistry-Paraffin: GSDMDC1 Antibody [NBP2-33422] - Liver 0.1 mL Log in to see 10至13个工作日
$491.63
详细
小鼠 非结合性 ELISA, IF, IHC, WB Immunofluorescence of monoclonal antibody to GSDMDC1 on HeLa cell (antibody concentration 10 µg/mL). GSDMDC1 monoclonal antibody (M01), clone 3F12-1B2 Western Blot analysis of GSDMDC1 expression in Jurkat. 100 μg Log in to see 8至11个工作日
$461.00
详细
小鼠 非结合性 EIA, IF, IHC (p), WB 50 μg Log in to see 6至8个工作日
$445.50
详细
非结合性 WB Western blot analysis of extracts of mouse lung and rat liver cell lines, using GSDMD antibody. 100 μL Log in to see 16 Days
$334.77
详细
小鼠 非结合性 IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to GSDMDC1 on formalin-fixed paraffin-embedded human tonsil tissue. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to GSDMDC1 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 11至12个工作日
$440.00
详细
小鼠 非结合性 ELISA, IF, IHC (p), WB Immunohistochemistry-Paraffin: GSDMDC1 Antibody (3F12-1B2) [NBP1-69898] - Analysis of anti-GSDMD / DFNA5L antibody with human small intestine at concentration 5 ug/ml. 0.05 mg Log in to see 34 Days
$585.06
详细
非结合性 IHC, WB Western blot analysis of extracts of Jurkat cells, using GSDMD antibody. 100 μL Log in to see 11至12个工作日
$390.77
详细
非结合性 WB Western Blot: GSDMDC1 Antibody [NBP2-14973] - Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE, antibody diluted at 1:500. 0.1 mL Log in to see 8至11个工作日
$514.63
详细
非结合性 WB Western Blot analysis of GSDMD expression in transfected 293T cell line by GSDMD MaxPab polyclonal antibody.<br><br>Lane 1: GSDMDC1 transfected lysate(52.80 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Log in to see 11至12个工作日
$425.71
详细
小鼠 非结合性 WB Western Blot analysis of GSDMD expression in transfected 293T cell line by GSDMD MaxPab polyclonal antibody.<br><br>Lane1:GSDMDC1 transfected lysate(53.24 KDa).<br>Lane2:Non-transfected lysate.<br> 50 μg Log in to see 11至12个工作日
$440.00
详细

引用最多的anti-Gasdermin D 抗体

  1. Human Polyclonal GSDMD Primary Antibody for ICC, IF - ABIN4316340 : Liu, Zhang, Ruan, Pan, Magupalli, Wu, Lieberman: Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. in Nature 2016 (PubMed)
    Show all 4 Pubmed References

更多抗Gasdermin D的相互作用对抗体

Human Gasdermin D (GSDMD) interaction partners

  1. The present study not only contributes to our understanding of GSDMD recognition by inflammatory caspases but also reports a specific inhibitor for these caspases that can serve as a tool for investigating inflammasome signaling.

  2. Pyroptosis regulator gasdermin D was necessary for IL-1beta (显示 IL1B 抗体) secretion from living macrophages that have been exposed to inflammasome activators, such as bacteria and their products or host-derived oxidized lipids

  3. These findings reveal that GSDMD-C acts as an auto-inhibition executor and GSDMD-N could form pore structures via a charge-charge interaction upon cleavage by caspases during cell pyroptosis.

  4. This study reveals the pore-forming activity of GSDMD and channel-forming activity of MLKL determine different ways of plasma membrane rupture in pyroptosis and necroptosis.

  5. GsdmD p30 (显示 CENPV 抗体) kills cells by forming pores that compromise the integrity of the cell membrane.

  6. Data, including data from studies using recombinant fusion forms of GSDMD, suggest that GSDMD participates in inflammasome-dependent pyroptosis of macrophages in response to various stimuli; this mechanism involves proteolysis of GSDMD by caspase-1 (显示 CASP1 抗体) and caspase-11 (显示 CASP4 抗体).

  7. Remarkably, the Enterovirus 71 protease 3C directly targets GSDMD and induces its cleavage, which is dependent on the protease activity.

  8. The pyroptosis is redefined as gasdermin D-mediated programmed necrosis. Gasdermin D are associated with various genetic diseases, and their cellular function and mechanism of activation.

  9. Overall, these data demonstrate that GSDMD is the direct and final executor of pyroptotic cell death.

  10. Studies show that the membrane-pores composed of gasdermin D-N domains (GSDMD-N domain) are required for pyroptosis.

Mouse (Murine) Gasdermin D (GSDMD) interaction partners

  1. The present study not only contributes to our understanding of GSDMD recognition by inflammatory caspases but also reports a specific inhibitor for these caspases that can serve as a tool for investigating inflammasome signaling.

  2. This study reveals the pore-forming activity of GSDMD and channel-forming activity of MLKL determine different ways of plasma membrane rupture in pyroptosis and necroptosis.

  3. Gene deletion of GSDMD demonstrated that GSDMD is required for pyroptosis and for the secretion but not proteolytic maturation of IL-1beta (显示 IL1B 抗体) in both canonical and non-canonical inflammasome responses.

  4. identification of gasdermin D (Gsdmd) by genome-wide clustered regularly interspaced palindromic repeat (CRISPR)-Cas9 nuclease (显示 DCLRE1C 抗体) screens of caspase-11 (显示 CASP4 抗体)- and caspase-1 (显示 CASP1 抗体)-mediated pyroptosis in mouse bone marrow macrophages

  5. gasdermin D is essential for caspase-11-dependent pyroptosis and interleukin-1beta maturation

  6. This study clearly shows that Gsdmd is not essential for development of mouse intestinal tract or epithelial cell differentiation.

Gasdermin D (GSDMD) 抗原简介

蛋白简介

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with anti-Gasdermin D (GSDMD) 抗体

  • gasdermin D (GSDMD) 抗体
  • gasdermin D (Gsdmd) 抗体
  • 1810036L03Rik 抗体
  • AW558049 抗体
  • DF5L 抗体
  • Dfna5l 抗体
  • GSDMD 抗体
  • Gsdmdc1 抗体
  • M2-4 抗体

Protein level used designations for anti-Gasdermin D (GSDMD) 抗体

gasdermin domain containing 1 , gasdermin-D , gasdermin D , gasdermin domain-containing protein 1

GENE ID SPECIES
513939 Bos taurus
609395 Canis lupus familiaris
697137 Macaca mulatta
739712 Pan troglodytes
100604427 Nomascus leucogenys
79792 Homo sapiens
69146 Mus musculus
315084 Rattus norvegicus
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