anti-Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) 抗体

GDAP1 encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. 再加上,我们可以发GDAP1 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
GDAP1 54332 Q8TB36
GDAP1 14545 O88741
GDAP1 312890  
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Showing 10 out of 36 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 IHC, IHC (p) Immunohistochemistry: GDAP1 Antibody [NBP1-84429] - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells. Immunohistochemistry-Paraffin: GDAP1 Antibody  - Staining of human cerebral cortex shows cytoplasmic positivity in neuronal cells. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: GDAP1 Antibody [NBP1-84430] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells. Immunocytochemistry/Immunofluorescence: GDAP1 Antibody [NBP1-84430] - Staining of human cell line A549 shows positivity in cytoplasm & mitochondria. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
非结合性 IHC, WB Western blot analysis of extracts of various cell lines, using GDAP1 antibody (ABIN5973967) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded rat kidney using GDAP1 antibody (ABIN5973967) at dilution of 1/100 (40x lens). 100 μL Log in to see 11至16个工作日
$426.40
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小鼠 非结合性 ELISA, WB GDAP1 polyclonal antibody (A01), Lot # 060613JCS1 Western Blot analysis of GDAP1 expression in HepG2 . Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 11至12个工作日
$305.71
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Bat 非结合性 WB   50 μg Log in to see 7至9个工作日
$551.83
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非结合性 WB   50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 IHC, WB Western blot analysis of extracts of various cell lines, using GDAP1 antibody. Immunohistochemistry of paraffin-embedded rat kidney using GDAP1 antibody. 100 μL Log in to see 13至14个工作日
$411.13
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非结合性 WB 100 μL Log in to see 11至18个工作日
$369.55
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引用最多的anti-GDAP1 抗体

  1. Human Polyclonal GDAP1 Primary Antibody for ELISA, WB - ABIN565729 : Cassereau, Chevrollier, Gueguen, Malinge, Letournel, Nicolas, Richard, Ferre, Verny, Dubas, Procaccio, Amati-Bonneau, Bonneau, Reynier: Mitochondrial complex I deficiency in GDAP1-related autosomal dominant Charcot-Marie-Tooth disease (CMT2K). in Neurogenetics 2009 (PubMed)
    Show all 3 Pubmed References

更多抗GDAP1的相互作用对抗体

Human Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) interaction partners

  1. Study expands the mutational spectrum of GDAP1-related Charcot-Marie-Tooth (CMT) disease with the identification of new and unreported GDAP1 variants and demonstrates the predominance of the axonal form of neuropathy in CMT disease associated with GDAP1; highlights the clinical characteristics associated with these genotypes and describe the relative frequency of GDAP1 variants amongst the Chinese population.

  2. Study shows that GDAP1 is indeed a GST (显示 SLCO6A1 抗体) enzyme, and demonstrates a specific GSH-conjugating activity in vitro which seems to be regulated by the hydrophobic domain 1 (HD1 (显示 HDAC1 抗体)) exerting an autoinhibitory function. HD1 (显示 HDAC1 抗体) could adopt an amphipathic pattern necessary to induce remodeling of organelles-mimicking liposomes by Gdap1.

  3. We identified GDAP1 variants in approximately 1% of our cohort with IPNs, and established a founder mutation in half of these patients. Our study originally described the mutational spectrum and clinical features of GDAP1-related CMT patients in Japan.

  4. This study report an AD-CMT2K with large phenotypic variability due to a novel dominant GDAP1 variant.

  5. GDAP1 hypomethylation can serve as a biomarker for alcohol dependence severity and treatment outcome.

  6. This study suggest GDAP1 as the first gene that should be analysed in Italian patients affected by CMT2.

  7. study reports on 2 Charcot-Marie-Tooth (CMT) families in which a newly identified Glu222Lys mutation within the GDAP1 gene segregates both in autosomal dominant and recessive traits

  8. The novelty of our data is the relatively high frequency of SH3TC2 (显示 SH3TC2 抗体) and GDAP1 mutations in demyelinating and axonal forms, respectively, of Charcot-Marie-Tooth disease

  9. Results show that JPH1 (显示 JPH1 抗体) and GDAP1 share a common pathway and depend on each other; therefore, JPH1 (显示 JPH1 抗体) can contribute to the phenotypical consequences of GDAP1 mutations.

  10. GDAP1-associated polyneuropathy caused predominantly a mild and slowly progressive phenotype.

Mouse (Murine) Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) interaction partners

  1. absence of GDAP1 induces a peripheral neuropathy with loss of motor neurons, mitochondrial defects and abnormal calcium homeostasis.

  2. Members of the GDAP1 family are responsive and protective against stress associated with increased levels of oxidized glutathione.

  3. Cell expression of Gdap1 in the nervous system and pathogenesis of Charcot-Marie-Tooth type 4A disease are reported.

GDAP1 抗原简介

蛋白简介

This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene.

Gene names and symbols associated with GDAP1

  • ganglioside induced differentiation associated protein 1 (GDAP1) 抗体
  • ganglioside-induced differentiation-associated-protein 1 (Gdap1) 抗体
  • CMT4 抗体
  • CMT4A 抗体
  • CMTRIA 抗体

Protein level used designations for GDAP1

ganglioside-induced differentiation-associated protein 1 , Charcot-Marie-Tooth neuropathy 4A , ganglioside differentiation associated protein 1

GENE ID SPECIES
100172660 Pongo abelii
100050935 Equus caballus
54332 Homo sapiens
420191 Gallus gallus
487002 Canis lupus familiaris
100157012 Sus scrofa
613472 Bos taurus
14545 Mus musculus
312890 Rattus norvegicus
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