GTP Cyclohydrolase I Feedback Regulator 蛋白 (GCHFR)

GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. 再加上,我们可以发GCHFR 抗体 (65)GCHFR 试剂盒 (7)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
GCHFR 2644 P30047
GCHFR 320415 P99025
GCHFR 171128 P70552
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Showing 7 out of 9 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$5,465.26
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大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$5,465.26
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大肠杆菌(E. Coli) His tag 100 μg Log in to see 13至16个工作日
$400.00
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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酵母菌 大鼠 His tag   1 mg Log in to see 60至71个工作日
$2,123.00
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酵母菌 Cow His tag   1 mg Log in to see 60至71个工作日
$2,123.00
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酵母菌 Xenopus tropicalis His tag   1 mg Log in to see 60至71个工作日
$2,124.83
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GCHFR 蛋白 by Origin and Source

Origin 在表达 标记
Human ,
,
Mouse (Murine)

Rat (Rattus)

更多GTP Cyclohydrolase I Feedback Regulator (GCHFR)互动伙伴

Human GTP Cyclohydrolase I Feedback Regulator (GCHFR) interaction partners

  1. homozygous individuals for the TT haplotype were less likely to respond to the SSRI fluoxetine than to the nortriptyline suggesting a biological process through which GCHFR promoter variants might influence antidepressant response.

  2. Studies provide a new mechanism for regulation of endothelial GTPCH-1 (显示 GCH1 蛋白) by its phosphorylation and interplay with GFRP.

  3. Bacterial lipopolysaccharide down-regulates expression of GTP cyclohydrolase I feedback regulatory protein

  4. allosteric regulation of GTPCH-I activity in the cardiovascular system maybe an important mechanism regulating BH4 levels through GTPCH-I feedback regulatory protein signaling

  5. GFRP/GTPCHI (显示 GCH1 蛋白) axis functions in epidermal keratinocytes and melanocytes in the cytosol and nucleus.

  6. GCH1 (显示 GCH1 蛋白) mutations in Japanese patients with DYT5 (显示 GCH1 蛋白) dystonia. In some of them, the GCH1 (显示 GCH1 蛋白) enzyme activity was proved to be impaired.

  7. The co-expression of GTP cyclohydrolase I (显示 GCH1 蛋白) (GCHI) with tyrosine hydroxylase (TH (显示 TH 蛋白)) indicates that TH is indeed active in human neurosecretory neurons.

  8. Demonstrate role for GFRP in regulating iNOS (显示 NOS2 蛋白)-mediated NO synthesis and suggest that the allosteric regulation of GTP (显示 AK3 蛋白)-CH1 activity by GFRP may be an important mechanism regulating BH(4) and NO levels in vivo.

  9. 6BH(4) de novo synthesis is controlled by H(2)O(2) in a concentration-dependent manner, but H(2)O(2)-mediated oxidation does not affect the functionality of the GTPCHI (显示 GCH1 蛋白)/GFRP complex.

Mouse (Murine) GTP Cyclohydrolase I Feedback Regulator (GCHFR) interaction partners

  1. Studies provide a new mechanism for regulation of endothelial GTPCH-1 (显示 GCH1 蛋白) by its phosphorylation and interplay with GFRP (显示 NR4A1 蛋白).

  2. GTPCH (显示 GCH1 蛋白) expression is the primary regulator of BH4 levels, and changes in GTPCH (显示 GCH1 蛋白) or BH4 are not necessarily accompanied by changes in GFRP (显示 NR4A1 蛋白) expression.

蛋白简介GCHFR

蛋白简介

GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.

Gene names and symbols associated with GCHFR

  • GTP cyclohydrolase I feedback regulator (GCHFR)
  • GTP cyclohydrolase I feedback regulator (Gchfr)
  • 2010323F13Rik 蛋白
  • GFRP 蛋白
  • HsT16933 蛋白
  • P35 蛋白

Protein level used designations for GCHFR

GTP cyclohydrolase I feedback regulator , GTP cyclohydrolase 1 feedback regulatory protein , GTP cyclohydrolase I feedback regulatory protein , GFRP , p35

GENE ID SPECIES
100220034 Taeniopygia guttata
2644 Homo sapiens
617650 Bos taurus
320415 Mus musculus
171128 Rattus norvegicus
423003 Gallus gallus
100153745 Sus scrofa
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