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GCH1 蛋白

(GTP Cyclohydrolase 1 (GCH1))
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described\; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008].
GCH1 Protein (AA 1-250) (GST tag) GCH1 Protein (AA 1-250) (GST tag) GCH1 Protein (AA 1-250) (GST tag) (ABIN1354910)

GCH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

GCH1 Protein (AA 84-172) (GST tag) GCH1 Protein (AA 84-172) (GST tag) GCH1 Protein (AA 84-172) (GST tag) (ABIN1354912)

GCH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

GCH1 Protein (AA 12-241) (His tag) GCH1 Protein (AA 12-241) (His tag) GCH1 Protein (AA 12-241) (His tag) (ABIN3121448)

Crystallography grade GCH1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys

GCH1 蛋白 by Grade

Find GCH1 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

GCH1 蛋白 by Origin

Find GCH1 蛋白 for a variety of species such as anti-Human GCH1, anti-Mouse GCH1, anti-Rat GCH1. The species listed below are among those available. Click on a link to go to the corresponding products.

GCH1 蛋白 by Source

Here you will find GCH1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

GCH1 蛋白 by 蛋白类型

Here you can find GCH1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

GCH1 蛋白 by 应用范围

Find GCH1 蛋白 validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular GCH1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1354910
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354912
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3121448
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3080453
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422661
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2750202
Quantity 5 applications
Datasheet Datasheet
Reactivity Velvet bean (Mucuna pruriens)
Source Yeast
Validations
Cat. No. ABIN1608968
Quantity 1 mg
Datasheet Datasheet
Reactivity Euglena gracilis
Source Yeast
Validations
Cat. No. ABIN1461743
Quantity 1 mg
Datasheet Datasheet
Reactivity Rainbow Trout
Source Yeast
Validations
Cat. No. ABIN1608986
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1474106
Quantity 1 mg
Datasheet Datasheet
Reactivity Chicken
Source Yeast
Validations
Cat. No. ABIN1459043
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GCH1 蛋白

Widder, Chen, Li, Dikalov, Thöny, Hatakeyama, Harrison: "Regulation of tetrahydrobiopterin biosynthesis by shear stress." in: Circulation research, Vol. 101, Issue 8, pp. 830-8, (2007) (PubMed).

Aliases for GCH1 蛋白

GTP cyclohydrolase 1 (GCH1) 蛋白
GTP cyclohydrolase 1 (Gch1) 蛋白
GTP cyclohydrolase 1 (gch1) 蛋白
GTP cyclohydrolase 1 (Weevi_1190) 蛋白
GTP cyclohydrolase 1 (Halhy_0838) 蛋白
GTP cyclohydrolase 1 (Sinme_1220) 蛋白
GTP cyclohydrolase 1 (Sphch_1077) 蛋白
GTP cyclohydrolase 1-like (LOC100136794) 蛋白
DYT5 蛋白
DYT5a 蛋白
DYT14 蛋白
GCH 蛋白
Gch 蛋白
gch1a 蛋白
GTP-CH 蛋白
GTP-CH-1 蛋白
GTPCH 蛋白
GTPCH1 蛋白
HPABH4B 蛋白
MGC89622 蛋白
wu:fc16b10 蛋白
zgc:195269 蛋白
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