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Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. 再加上，我们可以发GSX2 蛋白 (3)和数多这个蛋白质的别的产品。
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Gsx2 is required in septal progenitors for the correct expansion of subventricular zone progenitors specified toward the calretinin (显示 CALB2 抗体)(+) subtype
we generated a transgenic mouse line driving Cre and EGFP expression with two putative cis (显示 CISH 抗体)-regulatory modules upstream of the homeobox (显示 PRRX1 抗体) gene Gsx2 , a critical gene for establishing lateral ganglionic eminence (LGE) identity.
homeodomain transcription factor Gsx2 plays a crucial role in the region-specific control of adult neural stem cells in both persistent and injury-induced neurogenesis
despite their redundant properties, Gsx1 and -2 have distinct interactions with Dlx1 and -2
high levels of Gsx2 suppress dendrocyte precursor cells specification in lateral ganglionic eminence progenitors; its downregulation is required for the transition from neurogenesis to oligodendrogenesis
Results show that Gsx1 (显示 GSX1 抗体) and Gsx2 differentially regulate the maturation of LGE progenitors.
repression of Ngn1 (显示 NEUROG1 抗体) by Gsh2 promotes the differentiation of dI3 interneurons
By analysis of Gsh2 in mutant mice, it can be demonstrated that Gsh2 along with Pax6 (显示 PAX6 抗体) are directly required for major aspects of pallial-subpallial boundary progenitor cell specification.
Data show that in the Gsx2 mutants Gsx1 (显示 GSX1 抗体) is expressed in only a subset of the ventral telencephalic progenitors that normally express Gsx2.
This study identified and validated a three-gene (EMP3, GSX2 and EMILIN3) prognostic signature in Lower-Grade Gliomas.
Data show that GS Homeobox 2 (Gsx2) and Early B-cell factor 1 (Ebf1 (显示 EBF1 抗体)) combined overexpression in human embryonic stem (hES (显示 RRBP1 抗体)) cells achieves high yields of medium spiny neurons (MSNs).
4q12 translocations with GSX2 expression identify a CD7 (显示 CDK7 抗体)(+) acute myeloid leukaemia subset.
Gsx2 negatively regulates neurogenesis from postnatal progenitor cells.
Transgenic mice lacking microRNAs miR (显示 MLXIP 抗体)-9-2 and miR (显示 MLXIP 抗体)-9-3 exhibit multiple defects of telencephalic structures which may be brought about by dysregulation of Foxg1 (显示 FOXG1 抗体), Nr2e1 (显示 NR2E1 抗体), Gsh2, and Meis2 (显示 MEIS2 抗体) expression.
ectopically expressed in myeloid leukemic cells with t(4;12)(q11-q12;p13), suggesting that expression of GSH2 was deregulated by the translocation, indicating a variant leukemogenic mechanism for translocations involving the 5' end of ETV6 (显示 ETV6 抗体)
Gsx2 specifies striatal projection neuron and olfactory bulb interneuron identity at distinct time points during neurogenesis in transgenic mice.
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
genomic screened homeo box 2
, homeobox protein GSH-2
, genomic screened homeo box 2 protein
, GS homeobox 2
, GS homeobox 2-like
, genomic-screened homeobox 2