GDNF Family Receptor alpha 2 (GFRA2) ELISA试剂盒

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. 再加上,我们可以发GFRA2 抗体 (72)GFRA2 蛋白 (17)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
GFRA2 2675 O00451
小鼠 GFRA2 GFRA2 14586  
大鼠 GFRA2 GFRA2 25136  
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适于 GFRA2 相互作用对的更多 ELISA 试剂盒

Human GDNF Family Receptor alpha 2 (GFRA2) interaction partners

  1. The cardiac GFRA2 signaling pathway is distinct from the canonical pathway dependent on the RET (显示 RET ELISA试剂盒) tyrosine kinase (显示 TXK ELISA试剂盒).

  2. High GFRalpha2 expression level leads to PTEN inactivation via Mir-17-5p up-regulation, promoting pancreatic tumor cell growth and chemoresistance.

  3. GFRA2 variants associated with diabetic neuropathic pain.

  4. The study shows co-localization of RET (显示 RET ELISA试剂盒) with GFRA1 (显示 GFRA1 ELISA试剂盒) and GFRA2 in myenteric ganglia of the adult human colon.

  5. Cyclic AMP (显示 APRT ELISA试剂盒) signalling through PKA but not Epac is essential for neurturin (显示 NRTN ELISA试剂盒)-induced biphasic ERK1/2 (显示 MAPK1/3 ELISA试剂盒) activation and neurite outgrowths through GFRalpha2 isoforms.

  6. GFRA2 genetic variants, and age, may play a role in susceptibility to tardive dyskinesia.

  7. This study found nominally-significant evidence for interactions between GFRA1 (显示 GFRA1 ELISA试剂盒), 2 and 3 associated with schizophrenia and clozapine response, consistent with the locations of these three genes within linkage regions for schizophrenia.

  8. Both GFR alpha2a and GFR alpha2c, but not GFR alpha2b, promote neurite outgrowth in transfected Neuro2A cells.

Mouse (Murine) GDNF Family Receptor alpha 2 (GFRA2) interaction partners

  1. The cardiac GFRA2 signaling pathway is distinct from the canonical pathway dependent on the RET (显示 RET ELISA试剂盒) tyrosine kinase (显示 TYRO3 ELISA试剂盒).

  2. Ret (显示 RET ELISA试剂盒) and Gfra2 null mice display comparable early central projection deficits, but Gfra2 null rapidly adapting mechanoreceptors recover later.

  3. STAT3 (显示 STAT3 ELISA试剂盒) phosphorylation by neurturin (显示 NRTN ELISA试剂盒) was found to be mediated specifically by GFRalpha2c and RET9 (显示 RET ELISA试剂盒) isoforms.

  4. Cholinergic innervation of gastric mucosa depends on neurturin (显示 NRTN ELISA试剂盒)-GFRalpha2 signalling but is dispensable for gastrin (显示 GAST ELISA试剂盒) secretion and for basal and maximal acid output

  5. our data demonstrate that RET (显示 RET ELISA试剂盒)/GFRalpha signals are dispensable for thymic T cell development in vivo

  6. Transduction-function role for GFR (显示 RAPGEF5 ELISA试剂盒) alpha2/neurturin (显示 NRTN ELISA试剂盒) signalling in a specific class of sensory neurons.

  7. The cholinergic subpopulation of sympathetic neurons requires GFR alpha 2 signaling for soma size and for growth or maintenance of target innervation.

  8. Demonstrate a role for GFRalpha2-expressing enteric neurons in the downstream signaling of the glucagon (显示 GCG ELISA试剂盒)-like peptides to inhibit GI motility, but not in intestinal growth.

GFRA2 抗原简介

Antigen Summary

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GFRA2

  • GDNF family receptor alpha 2 (GFRA2) 抗体
  • glial cell line derived neurotrophic factor family receptor alpha 2 (Gfra2) 抗体
  • GDNF family receptor alpha 2 (Gfra2) 抗体
  • GDNF family receptor alpha 2 (gfra2) 抗体
  • GDNF family receptor alpha 2a (gfra2a) 抗体
  • gdnfrb 抗体
  • gfra2 抗体
  • nrtnr-alpha 抗体
  • ntnra 抗体
  • NTNRALPHA 抗体
  • retl2 抗体
  • trnr2 抗体

Protein level used designations for GFRA2

GDNF family receptor alpha-2 , GDNF receptor beta , GDNFR-alpha-2 , GDNFR-beta , GFR-alpha 2 , NTNR-alpha , PI-linked cell-surface accessory protein , RET ligand 2 , TGF-beta-related neurotrophic factor receptor 2 , TRN receptor, GPI-anchored , glial cell line derived neurotrophic factor receptor, beta , neurturin receptor alpha , GDNF receptor alpha-2 , GFR alpha 2 , GFR alpha-2 , GFR-alpha-2 , NRTNR-alpha , CDC42 binding protein kinase alpha (DMPK-like) , glial cell line derived neurotrophic factor family receptor alpha 2 , tyrosine kinase receptor ligand 2 , GDNF family receptor alpha 2 , GDNF family receptor alpha-2-like

GENE ID SPECIES
2675 Homo sapiens
14586 Mus musculus
100157850 Sus scrofa
25136 Rattus norvegicus
395993 Gallus gallus
514036 Bos taurus
100127717 Xenopus (Silurana) tropicalis
100171804 Pongo abelii
405794 Danio rerio
609172 Canis lupus familiaris
100475044 Ailuropoda melanoleuca
100727079 Cavia porcellus
100146260 Equus caballus
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