Free Fatty Acid Receptor 2 (FFAR2) ELISA试剂盒

FFAR2 encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. 再加上,我们可以发FFAR2 抗体 (94)FFAR2 蛋白 (7)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
FFAR2 2867 O15552
FFAR2 292794 Q76EI6
FFAR2 233079 Q8VCK6
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适于 FFAR2 相互作用对的更多 ELISA 试剂盒

Human Free Fatty Acid Receptor 2 (FFAR2) interaction partners

  1. Data suggest that the free fatty acid receptor 2 (FFA2/GPR43 receptor) plays an integral role in survival during and after sepsis.

  2. we show functional similarities but also some important differences between GPR84 and FFA2R in human phagocytes, thus providing some mechanistic insights into GPR84 regulation in blood neutrophils and cells recruited to an aseptic inflammatory site in vivo.

  3. Compared with the control group, the densitometric quantification and mean density of GPR43 and ChAT proteins, and expression of GPR43 and CHAT genes, were significantly decreased in the patients with mixed refractory constipation.

  4. a single dose of soluble fibre was able to significantly reduce airway inflammation in stable asthma by downregulating GPR43 and GPR41 (显示 FFAR3 ELISA试剂盒)

  5. Short-chain fatty acids lowered TNF-alpha (显示 TNF ELISA试剂盒)-induced MCP-1 (显示 CCL2 ELISA试剂盒) expression by reducing phosphorylation of p38 MAPK (显示 MAPK14 ELISA试剂盒) and JNK (显示 MAPK8 ELISA试剂盒) in a GPR41 (显示 FFAR3 ELISA试剂盒)/GRP43-dependent manner in renal cortical epithelial cells.

  6. FFA2 processes mediated by Gi signaling, whereas, in concert with blockade by the Gq/G11 inhibitor FR900359, the inability of AZ1729 to mimic or regulate propionate-mediated release of GLP-1 from mouse colonic preparations defined this physiological response as an end point transduced via activation of Gq/G11.

  7. the results of mutagenesis studies based on the crystal structure of hFFA1 bound to TAK (显示 CDK9 ELISA试剂盒)-875 at 2.3 A resolution to identify important residues for orthosteric agonist 6e inducing FFA2 activation.

  8. Although both agonist and antagonist ligands contain negatively charged carboxylates that interact with two key positively charged arginine residues in transmembrane domains V and VII (显示 TH ELISA试剂盒) of FFA2, there are clear differences in how these interactions occur.

  9. FFAR2 signaling occurs by divergent G protein pathways.

  10. GPR3 agonism potentiates insulin secretion in isolated islets.

Mouse (Murine) Free Fatty Acid Receptor 2 (FFAR2) interaction partners

  1. this study shows that free fatty acid receptor 2 promotes beta-cell proliferation

  2. this paper show that microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA (显示 IgA ELISA试剂盒) response to microbiota which is mediated by GPR43

  3. dual oxidase-2 (显示 DUOX1 ELISA试剂盒) and IL-6 (显示 IL6 ELISA试剂盒) play important roles in GPR43-mediated skin inflammation.

  4. Loss of Ffar2 expression is associated with leukemia.

  5. the role of GPR43 in adipose tissue macrophages, was examined.

  6. loss of FFAR2 is associated with colon tumorigenesis.

  7. Gestational glucose tolerance in WT mice, but not Ffar2-/- mice improved while on antibiotics. Gestational glucose tolerance worsened in Ffar2-/- mice during a second pregnancy. Maternal Ffar2 expression had no effect on the growth rates and glucose and glucose tolerance in the offspring.

  8. FFA2 processes mediated by Gi signaling, whereas, in concert with blockade by the Gq/G11 inhibitor FR900359, the inability of AZ1729 to mimic or regulate propionate-mediated release of GLP-1 from mouse colonic preparations defined this physiological response as an end point transduced via activation of Gq/G11.

  9. A Western diet could aggravate the inflammatory colitis process; the activation of the GPR43 receptor pathway could be used as a new strategy to treat Crohn's Disease patients.

  10. FFAR2 signaling occurs by divergent G protein pathways.

FFAR2 抗原简介

Antigen Summary

This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels.

Gene names and symbols associated with FFAR2

  • free fatty acid receptor 2 (FFAR2) 抗体
  • free fatty acid receptor 2 (Ffar2) 抗体
  • FFA2R 抗体
  • GPCR43 抗体
  • Gpr43 抗体

Protein level used designations for FFAR2

G protein-coupled receptor 43 , G-protein coupled receptor 43 , free fatty acid activated receptor 2 , leukocyte-specific STAT-induced GPCR

GENE ID SPECIES
2867 Homo sapiens
292794 Rattus norvegicus
233079 Mus musculus
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