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FOXL1 encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors.
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Human Monoclonal FOXL1 Primary Antibody for IHC (p), ELISA - ABIN515694
Yang, Yang, Li, Liu, Wang, Che, Huang, Zheng: Foxl1 inhibits tumor invasion and predicts outcome in human renal cancer. in International journal of clinical and experimental pathology 2014
Drosophila FoxL1 homologue is expressed in the VIS5 somatic muscles and in homologous abdominal muscles. FoxL1 functions nonautonomously to affect the salivary glands, Malpighian tubules and germ cells. FoxL1-dependent expression of secreted Sema2a in T3 VIS5 is required for normal salivary gland positioning. It functions like its mammalian counterpart in non-autonomously orchestrating behaviors of surrounding tissue.
FOXL1 inhibited the proliferation, invasion, and migration of breast cancer.FOXL1 expression was reduced in breast cancer.
our findings provide evidence that FOXL1 might serve as a candidate tumor suppressor and a potential prognostic biomarker for gastric cancer
the downregulation of FOXL1 expression was associated with osteosarcoma cell growth. Restoration of FOXL1 gene expression by gene therapy may have a therapeutic potential for patients with osteosarcoma
dysregulated FOXL1 is involved in tumorigenesis and progression of gallbladder cancer.
results suggest that Foxl1 plays an inhibitory role in renal tumor progression.
Lower FOXL1 expression is correlated with metastasis and advanced pathologic stage of pancreatic cancer.
two novel de novo mutations in rare patients inherited gene variants in FOXL1.
FUS (显示 FUS 抗体)-CREB3L2 (显示 CREB3L2 抗体)/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 (显示 CD24 抗体) and FOXL1.
SALL4 (显示 SALL4 抗体) associated with the NuRD co-repressor and repressed expression of the tumor suppressor genes Foxl1 and Dusp4 (显示 DUSP9 抗体).
Foxl1(+) hepatic progenitor cells and/or their descendants are required for the development of cholangiocytes and hepatocytes in liver injury models.
Foxl1 might be involved in cellular responses of gut (显示 GUSB 抗体)-associated lymphoid tissues dependent upon the Lymphotoxins/Lymphotoxin beta-receptor (显示 LTBR 抗体) axis.
link between a mesenchymal factor, Foxl1, and the regulation of a specific epithelial transport process in intestinal epithelium
Foxl1 is a bona fide marker of the facultative progenitor cell in the mouse liver.
promotes liver repair after bile-duct-ligation-induced liver injury through activation of the canonical wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) pathway
This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis.
forkhead box protein L1
, forkhead box L1
, forkhead transcription factor L1
, forkhead box L1 transcription factor
, forkhead-like 11
, forkhead-related protein FKHL11
, forkhead-related transcription factor 7
, forkhead homolog 6
, transcription factor FKH-6