FMO3 抗体
(Flavin Containing Monooxygenase 3 (FMO3))
Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.[provided by RefSeq, Aug 2009].
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FMO3 抗体 by 应用范围
Find FMO3 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
FMO3 抗体 by 抗体来源
Find FMO3 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
FMO3 抗体 by 克隆形成能力
Find available monoclonal or polyclonal FMO3 抗体. Click on a link to go to the corresponding products.
FMO3 抗体 by 克隆
Find FMO3 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular FMO3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN7267216
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN515768
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN2855649
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN947875
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6261772
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Rat, Xenopus laevis
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6754938
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN3015686
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN390888
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (1)
- (2)
Cat. No.
ABIN2781862
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, FACS
Validations
- (3)
Cat. No.
ABIN3002867
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7149956
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IF
Validations
- (1)
Cat. No.
ABIN7259921
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Human, Monkey, Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN6744773
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Horse, Human, Mouse, Pig, Rabbit, Xenopus laevis
Application
WB
Validations
- (1)
Cat. No.
ABIN6747268
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our FMO3 抗体
: "Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 19, Issue 9, pp. 1213-20, (2006) (PubMed).: "Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 30, Issue 10, pp. 1043-52, (2002) (PubMed).
Aliases for FMO3 抗体
flavin containing monooxygenase 3 (FMO3) 抗体flavin containing monooxygenase 3 (fmo3) 抗体
flavin containing monooxygenase 3 L homeolog (fmo3.L) 抗体
flavin containing monooxygenase 3 (Fmo3) 抗体
AW111792 抗体
dJ127D3.1 抗体
FM03 抗体
FMOII 抗体
MGC107820 抗体
TMAU 抗体
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