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The protein encoded by FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. 再加上，我们可以发Fibrinogen gamma Chain 试剂盒 (34) 和 Fibrinogen gamma Chain 蛋白 (21)和数多这个蛋白质的别的产品。
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Human Monoclonal FGG Primary Antibody for ICC, FACS - ABIN969142
Uitte de Willige, Standeven, Philippou, Ariëns: The pleiotropic role of the fibrinogen gamma' chain in hemostasis. in Blood 2009
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Human Monoclonal FGG Primary Antibody for ICC, ELISA - ABIN969141
Bowley, Okumura, Lord: Impaired protofibril formation in fibrinogen gamma N308K is due to altered D:D and "A:a" interactions. in Biochemistry 2009
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Human Monoclonal FGG Primary Antibody for IHC (p), PLA - ABIN560879
Horlock, Shakib, Mahdavi, Jones, Sewell, Ghaemmaghami et al.: Analysis of proteomic profiles and functional properties of human peripheral blood myeloid dendritic cells, monocyte-derived dendritic cells and the dendritic cell-like KG-1 cells reveals distinct ... in Genome biology 2007
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Human Polyclonal FGG Primary Antibody for IF (p), IHC (p) - ABIN872908
Li, He, Di, Yan, Zhang: Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice. in Life sciences 2016
Human Polyclonal FGG Primary Antibody for IHC, IHC (p) - ABIN4311663
Kampf, Mardinoglu, Fagerberg, Hallström, Edlund, Lundberg, Pontén, Nielsen, Uhlen: The human liver-specific proteome defined by transcriptomics and antibody-based profiling. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014
These data suggest that single nucleotide polymorphisms ABO (显示 ABO 抗体) rs8176719 and FGG rs2066865 may contribute individually to the venous thromboembolism susceptibility in the Portuguese population.
DNA sequencing revealed a novel heterozygous CCTTTGATG deletion in the exon 8 of FGG, leading to the deletion of Ala289, Phe290, and Asp291 in fibrinogen gamma-chain
Data defined the mutational burden of the fibrinogen FGA, FGB, and FGG genes, and estimated the prevalence of inherited fibrinogen disorders through a systematic analysis of exome/genome data.
The simultaneous retention of fibrinogen and APOB (显示 APOB 抗体)-lipoproteins in FSD can be detected in routinely stained histological sections. The analysis of protein structures unraveled the pathomorphogenesis of this unexpected phenomenon. Fibrinogen gamma chain mutations provoke conformational changes in the region of the globular domain involved in the "end-to-end" interaction, thus impairing the D-dimer formation
Fibrinogen gamma acts as thrombomodulin (显示 THBD 抗体) II. (Review)
Gene analysis of the fibrinogen phenotype reveals the importance of polygenic co-regulation.
Data indicate that repeated measurement after five hours showed a statistical significant difference for the fractional synthesis rate of fibrinogen but not for albumin (显示 ALB 抗体).
Fibrinogen gamma chain and complement factor H (显示 CFH 抗体) were found to be bound as a protein complex in the plasma of a patient with advanced ovarian cancer
The high preoperative peripheral serum fibrinogen level was related to poor survival in penile cancer patients, suggeting fibrinogen may serve as a powerful predictor of cancer specific survival (CSS (显示 CMAS 抗体)) in penile cancer patients.
These findings provide insight into assembly of the fibrinogen/FXIII-A2B2 complex in both physiologic and therapeutic situations.
Data suggest the potential compensatory role of fibrinogen in restoring coagulation function in vivo after hemorrhagic shock.
Report role of gamma'-fibrinogen in control of hemostatic clot (显示 TXNDC17 抗体) growth in the venous circulation.
Fibrinogen from mice harboring the Fibgamma390-396A mutation exhibited reduced binding to FXIII, and plasma from these mice exhibited delayed FXIII activation and fibrin crosslinking, indicating these residues mediate FXIII binding and activation.
elevated levels of gammaA/gammaA fibrinogen promote arterial thrombosis in vivo, whereas gammaA/gamma' does not
the gamma'/total fibrinogen ratio is associated with short-term outcome in ischaemic stroke
Platelet receptor engagement of the Fgg chain contributes to the stable incorporation of platelets into thrombi. Fibrinogen is internalized through alpha IIb beta 3 engagement of the Fgg chain; this interaction controls fibronectin (显示 FN1 抗体) content of platelets.
smaller thrombi result from the ability of fibrin to bind and sequester thrombin and/or the ability of the altered fibrinogen molecules, which cannot recruit platelets, to bind to and passivate the surface.
The Studies have shown that gamma chain binding to thrombin (显示 F2 抗体) and factor XIII (显示 UGDH 抗体) results in clots that are mechanically stiffer and resistant to fibrinolysis, which may explain the association between gammaA/gamma' fibrinogen levels and cardiovascular disease.
the engagement of alphaIIb beta3 by the C-terminal sequence of the fibrinogen gamma-chain initiates signals that suppress subsequent fibronectin (显示 FN1 抗体) assembly by spread platelets
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
fibrinogen, gamma chain
, fibrinogen gamma chain
, fibrinogen gamma chain-like
, fibrinogen, gamma polypeptide
, fibrinogen gamma polypeptide
, fibrinogen gamma-B chain
, fibrinogen gamma-chain
, gamma chain
, gamma polypeptide