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Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. 再加上，我们可以发Fem-1 Homolog B (C. Elegans) 蛋白 (6) 和 和数多这个蛋白质的别的产品。
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FEM1 proteins are ancient regulators of Stem-Loop Binding Protein (显示 SLBP 抗体).
These findings have implications for understanding the cellular functions of Fem1b, and the regulation of Gli1 (显示 GLI1 抗体) oncoprotein activity.
the proapoptotic protein Fem1b is downregulated by the proteasome in malignant colon cancer cells and mediates proteasome inhibitor-induced apoptosis of these cells
This study presents evidence suggesting a role for FEM1A (显示 FEM1A 抗体) and FEM1B in the pathogenesis of polycystic ovary syndrome. Only FEM1B variants were associated with insulin (显示 INS 抗体)-related traits in PCOS women.
FEM1B is required for Rad9 (显示 RAD9A 抗体) recruitment and CHK1 (显示 CHEK1 抗体) activation in response to replication stress.
Fem1b is a binding partner of Ankrd37, and their interaction resulted in Ankrd37 degradation through the ubiquitin-mediated proteolysis pathway.
Increased Fem1b is associated with intestinal neoplasia.
neither FEM1B nor PHTF1 (显示 PHTF1 抗体) are directly implicated in apoptosis in testis tissue
Fem1b is implicated in pancreatic islet function and insulin (显示 INS 抗体) secretion
Fem1b may have a conserved role in the generation of sexual dimorphism through its interaction with Nkx3.1 (显示 NKX3-1 抗体) in the developing prostate gland
Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet (By similarity). Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1 (By similarity).
FEM-1-like death receptor binding protein
, fem-1-like death receptor-binding protein alpha
, fem-1-like in apoptotic pathway protein alpha
, protein fem-1 homolog B
, feminization 1 homolog b
, fem-1 homolog b (C. elegans)