Fc Receptor-Like 2 蛋白 (FCRL2)

FCRL2 encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. 再加上,我们可以发FCRL2 抗体 (22)FCRL2 试剂盒 (2)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
FCRL2 79368 Q96LA5
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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人细胞 His tag SDS-PAGE 50 μg Log in to see 20至21个工作日
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FCRL2 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,

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Human Fc Receptor-Like 2 (FCRL2) interaction partners

  1. decreased FCRL4 (显示 FCRL4 蛋白) expression and association of FCRL2 expression with inflammatory markers and disease activity suggested the contribution of these molecules to rheumatoid arthritis inflammatory processes.

  2. FCRL2 overexpression in B cells from Hashimoto and Graves disease patients compared to normal subjects.

  3. a negative immunomodulatory function for FCRL2 in the regulation of memory B cells.

  4. B-CLL patients with high FCRL2 expression had a significantly longer treatment-free survival & overall survival than those with low FCRL2.

  5. FCRL2 has robust predictive value for determining IGHV gene mutation status and clinical progression and thus may further improve prognostic definition in chronic lymphocytic leukemia.

  6. Fc receptor-like 1 (显示 FCRL1 蛋白)-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia.

  7. Down-regulation of FCRL2 is associated with acute lymphoblastic leukemia.

蛋白简介FCRL2

蛋白简介

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with Fc Receptor-Like 2 蛋白 (FCRL2)

  • Fc receptor like 2 (FCRL2)
  • Fc receptor-like 2 (FCRL2)
  • Fc receptor-like protein 2 (LOC612038)
  • Fc receptor-like 2 L homeolog (fcrl2.L)
  • CD307b 蛋白
  • fcrh2 蛋白
  • ifgp4 蛋白
  • irta4 蛋白
  • spap1 蛋白
  • spap1a 蛋白
  • spap1b 蛋白
  • spap1c 蛋白

Protein level used designations for Fc Receptor-Like 2 蛋白 (FCRL2)

Fc receptor-like protein 2 , IFGP family protein 4 , SH2 domain containing phosphatase anchor protein 1 , SH2 domain-containing phosphatase anchor protein 1 , fc receptor homolog 2 , fcR-like protein 2 , immune receptor translocation-associated protein 4 , immunoglobulin receptor translocation-associated protein 4 , immunoglobulin superfamily Fc receptor, gp42 , Fc receptor-like 2 , type I TM-receptor XFL1.1b , Fc receptor-like protein 2-like

GENE ID SPECIES
79368 Homo sapiens
426461 Gallus gallus
469520 Pan troglodytes
612038 Canis lupus familiaris
718824 Macaca mulatta
779035 Xenopus laevis
100446148 Pongo abelii
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