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Fc Receptor, IgG, Low Affinity IV 蛋白

(Fc Receptor, IgG, Low Affinity IV (FCGR4))

Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Also acts as a receptor for the Fc region of immunoglobulin epsilon (PubMed:17558411, PubMed:18949059). Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578, PubMed:17558411, PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059). Does not display binding to IgG1 or IgG3 (PubMed:16039578). Mediates neutrophil activation by IgG complexes redundantly with Fcgr3 (PubMed:18097064). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (PubMed:25824719). Binds with low affinity to both the a and b allotypes of IgE (PubMed:18949059). Has also been shown to bind to IgE allotype a only but not to allotype b (PubMed:17558411). Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes (PubMed:18949059). Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions (PubMed:17558411, PubMed:18949059). {ECO:0000269|PubMed:16039578, ECO:0000269|PubMed:17558411, ECO:0000269|PubMed:18097064, ECO:0000269|PubMed:18949059, ECO:0000269|PubMed:19795417, ECO:0000269|PubMed:25824719}.

FCGR4 宿主: 小鼠宿主: 人细胞 Recombinant Greater than 95 % as determined by reducing SDS-PAGE. ELISA, MS, SDS, WB

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Find Fc Receptor, IgG, Low Affinity IV 蛋白 for a variety of species such as anti-Mouse Fc Receptor, IgG, Low Affinity IV. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular Fc Receptor, IgG, Low Affinity IV 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Fc Receptor, IgG, Low Affinity IV (FCGR4) (AA 21-203) protein (His tag)

Reactivity Mouse

Source Human Cells

Validations

Cat. No. ABIN7314672

Quantity 50 μg

Datasheet Datasheet

Aliases for Fc Receptor, IgG, Low Affinity IV 蛋白

Fc receptor, IgG, low affinity IV (Fcgr4) 蛋白
4833442P21Rik 蛋白
CD16-2 蛋白
FcgammaRIV 蛋白
Fcgr3a 蛋白
FcgRIV 蛋白
Fcrl3 蛋白

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