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Stimulates the proliferation of early hematopoietic cells by activating FLT3. 再加上，我们可以发FMS-Like tyrosine Kinase 3 Ligand 抗体 (7) 和 FMS-Like tyrosine Kinase 3 Ligand 蛋白 (6)和数多这个蛋白质的别的产品。
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Flt3L could enhance the efficacy of immune checkpoint blockades in glioblastoma via expanding CD103+ dendritic cells and downstream antitumor immune response.
Intratumoral administration of the STING agonist cyclic di-GMP (显示 NT5C2 ELISA试剂盒) (CDG) or Flt3 Ligand (Flt3L (显示 FLT3LG ELISA试剂盒)) augmented the therapeutic effect of systemic triple checkpoint modulation and promoted the cure of 75% of mice with bilateral TRAMP (显示 DPT ELISA试剂盒)-C2; however, when all agents were administered locally, only CDG mobilized abscopal immunity
both Flt3 ligand (FL (显示 FLT3LG ELISA试剂盒)) and IL-7 (显示 IL7 ELISA试剂盒) regulate B-cell commitment in a permissive manner: FL by inducing proliferation of Ly6D (显示 LY6D ELISA试剂盒)(+)CD135 (显示 FLT3 ELISA试剂盒)(+)CD127 (显示 IL7R ELISA试剂盒)(+)CD19 (显示 CD19 ELISA试剂盒)(-) progenitors and IL-7 (显示 IL7 ELISA试剂盒) by providing survival signals to these progenitors
Data show that FLT3 ligand (FLT3L (显示 FLT3LG ELISA试剂盒)) enhances thymopoiesis through increased survival and export of hematopoietic stem cell (Lin([minus])Sca1 (显示 ATXN1 ELISA试剂盒)(+)c-Kit (显示 KIT ELISA试剂盒)(+) [LSK (显示 LCK ELISA试剂盒)] cells via CXCR4 (显示 CXCR4 ELISA试剂盒) receptor regulation.
these results demonstrate that the lack of Flt3L (显示 FLT3LG ELISA试剂盒) mRNA expression in hematopoietic stem cells is yet another marker which further defines the status of long-term repopulating -hematopoietic stem cells
this study shows that ionizing radiation induces a decrease of CD8 (显示 CD8A ELISA试剂盒)+ dendritic cells and Th1 (显示 HAND1 ELISA试剂盒)/Th2 shift, which was reversed by Flt3 ligand (显示 FLT3LG ELISA试剂盒) treatment, suggesting a novel mechanism for radiation-induced immunosuppression
may be mediated by Flt3L (显示 FLT3LG ELISA试剂盒)- and MMP-9 (显示 MMP9 ELISA试剂盒)-dependent mobilization of dendritic cells
Bone marrow-derived CD117+ hematopoietic progenitor cells differentiate into thymic dendritic cells in the fetal thymus organ culture system in the presence of Flt3L (显示 FLT3LG ELISA试剂盒).
Flt3L (显示 FLT3LG ELISA试剂盒) significantly contributes to innate lymphoid cells and Peyer's patches development by targeting lymphoid progenitor cells during fetal and adult life.
unlike G-CSF (显示 CSF3 ELISA试剂盒), Flt3 (显示 FLT3 ELISA试剂盒)-L had an indirect effect on EI macrophages, as it was not detected at the surface of EI macrophages or erythroid progenitors.
Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
, fms-related tyrosine kinase 3 ligand
, fms-like tyrosine kinase 3 ligand