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The protein encoded by FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. 再加上，我们可以发FK506 Binding Protein 3, 25kDa 抗体 (70) 和 FK506 Binding Protein 3, 25kDa 试剂盒 (2)和数多这个蛋白质的别的产品。
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targets of FKBP25 and its complex with rapamycin
analysis of the expression pattern of the Fkbp25 gene during cerebral cortical neurogenesis
Taken together, these data clearly show that FKBP3/Sp1 (显示 PSG1 蛋白)/HDAC2 (显示 HDAC2 蛋白)/p27 (显示 PAK2 蛋白) control cell proliferation during non-small cell lung cancer development.
Data show that the N-terminus of FK506 binding protein (显示 FKBPL 蛋白)-25 (显示 IGFBPI 蛋白) (FKBP25) is anchored to regions of dsRNA, whereas the FKBP (显示 FKBP7 蛋白) domain is free to interact with neighboring proteins.
Structural basis for nucleic acid recognition by FKBP25 has been uncovered.
proteomics study indicates that the nuclear pool of the FKBP25 targets various nuclear proteins that are crucial for packaging of DNA, chromatin remodeling and pre-mRNA splicing
FKBP25 is likely recruited to preribosomes to chaperone one of the protein components of the ribosome large subunit.
structure of a unique N-terminal domain motif in the FKBP (显示 FKBP7 蛋白) family, FKBP25(1-73), high-resolution structures show a new fold composed of five small helices where H3 and H4 are tilted (显示 OTOP1 蛋白) in a novel arrangement; called Basic Tilted (显示 OTOP1 蛋白) Helix Bundle (BTHB) domain.
FKBP3, a novel regulator of the p53 (显示 TP53 蛋白) pathway, induces the degradation of MDM2 (显示 MDM2 蛋白) and activation of p53 (显示 TP53 蛋白).
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
25 kDa FK506-binding protein
, 25 kDa FKBP
, FK506-binding protein 3 (25kD)
, PPIase FKBP3
, immunophilin FKBP25
, peptidyl-prolyl cis-trans isomerase FKBP3
, rapamycin-selective 25 kDa immunophilin
, FK506 binding protein 3, 25kDa
, FK506-binding protein 25, T-cell
, rapamycin binding protein
, putative FK506-binding protein
, FK506-binding protein 3
, potential nucleolar FKBP-type peptidylprolyl cis/trans isomerase