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EXOSC10 抗体

(Exosome Component 10 (EXOSC10))
Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3'-5' exonuclease activity (By similarity). EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA (By similarity).
EXOSC10 抗体  (C-Term) EXOSC10 抗体  (C-Term) EXOSC10 抗体 (C-Term) (ABIN2778684)

EXOSC10 适用: 人, 小鼠, 兔, Cow, 大鼠, 犬, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated

EXOSC10 抗体  (AA 41-140) EXOSC10 抗体  (AA 41-140) EXOSC10 抗体 (AA 41-140) (ABIN1714746)

EXOSC10 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

EXOSC10 抗体  (AA 1-99) EXOSC10 抗体  (AA 1-99) EXOSC10 抗体 (AA 1-99) (ABIN518993)

EXOSC10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E6 unconjugated

EXOSC10 抗体 by 适用

Find EXOSC10 抗体 for a variety of species such as anti-Human EXOSC10, anti-Mouse EXOSC10, anti-Cow EXOSC10. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find EXOSC10 抗体 validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find EXOSC10 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

EXOSC10 抗体 by 克隆形成能力

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EXOSC10 抗体 by 克隆

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EXOSC10 抗体 by 标记

Find EXOSC10 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular EXOSC10 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN2778684
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (2)
Cat. No. ABIN1714746
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN518993
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Human, Mouse, Rabbit
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN203030
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5577605
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN7267062
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN2778683
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Mouse, Rabbit
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN6756542
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1701244
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN5002216
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN5002217
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1708636
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1710447
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1704867
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1703056
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our EXOSC10 抗体

Ogami, Richard, Chen, Hoque, Li, Moresco, Yates, Tian, Manley: "An Mtr4/ZFC3H1 complex facilitates turnover of unstable nuclear RNAs to prevent their cytoplasmic transport and global translational repression." in: Genes & development, (2017) (PubMed).

Hsin, Li, Hoque, Tian, Manley: "RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells." in: eLife, Vol. 3, pp. e02112, (2014) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Richard, Feng, Manley: "A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage." in: Genes & development, Vol. 27, Issue 20, pp. 2227-32, (2013) (PubMed).

van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).

Aliases for EXOSC10 抗体

exosome component 10 (exosc10) 抗体
exosome component 10 (EXOSC10) 抗体
exosome component 10 (EHI_021400) 抗体
exosome component 10 (BBOV_IV002650) 抗体
exosome component 10 (CpipJ_CPIJ003896) 抗体
exosome component 10 (CMU_031760) 抗体
3'-5' exonuclease (exosc10) 抗体
exosome component 10 (Tsp_05247) 抗体
exosome component 10 L homeolog (exosc10.L) 抗体
exosome component 10 (Exosc10) 抗体
21.m02990 抗体
201.t00018 抗体
DDBDRAFT_0203581 抗体
DDBDRAFT_0233752 抗体
DDB_0203581 抗体
DDB_0233752 抗体
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