anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) 抗体

DNA helicase that acts as an essential component of the spindle assembly checkpoint. 再加上,我们可以发Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ERCC6L 54821 Q2NKX8
ERCC6L 236930 Q8BHK9
ERCC6L 317252  
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-ERCC6L Antibody Titration: 0.2-1 ug/mlPositive Control: THP-1 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 WB Western Blot analysis of ERCC6L expression in transfected 293T cell line by ERCC6L MaxPab polyclonal antibody.Lane 1: ERCC6L transfected lysate(46.20 KDa).Lane 2: Non-transfected lysate. ERCC6L MaxPab rabbit polyclonal antibody. Western Blot analysis of ERCC6L expression in human colon. 100 μg Log in to see 11至12个工作日
$425.71
详细
小鼠 非结合性 ELISA, WB Detection limit for recombinant GST tagged ERCC6L is approximately 0.03ng/ml as a capture antibody. Western Blot analysis of ERCC6L expression in transfected 293T cell line by ERCC6L monoclonal antibody (M01), clone 3F12-2B10.Lane 1: ERCC6L transfected lysate(46.2 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 11至12个工作日
$440.00
详细
非结合性 WB Western Blot: ERCC6L Antibody [NBP1-56332] - THP-1 cell lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8至11个工作日
$488.73
详细
非结合性 ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: ERCC6L Antibody [NBP2-13969] - Staining of human cell line U-2 OS shows positivity in centrosome. Immunohistochemistry-Paraffin: ERCC6L Antibody [NBP2-13969] - Staining of human pancreas shows strong cytoplasmic and nuclear positivity in exocrine glandular cells. 0.1 mL Log in to see 10至13个工作日
$494.38
详细
非结合性 WB 100 μL Log in to see 11至13个工作日
$366.77
详细
非结合性 IP, WB Immunoprecipitation of ERCC6L transfected lysate using anti-ERCC6L MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with ERCC6L purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of ERCC6L expression in transfected 293T cell line by ERCC6L MaxPab polyclonal antibody.Lane 1: ERCC6L transfected lysate(46.2 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 11至12个工作日
$425.71
详细
小鼠 非结合性 WB Western Blot analysis of ERCC6L expression in transfected 293T cell line by ERCC6L MaxPab polyclonal antibody.Lane 1: ERCC6L transfected lysate(46.09 KDa).Lane 2: Non-transfected lysate. ERCC6L MaxPab polyclonal antibody. Western Blot analysis of ERCC6L expression in HeLa. 50 μg Log in to see 11至12个工作日
$440.00
详细
FITC IF (p)   100 μL Log in to see 14至21个工作日
$416.90
详细
Alexa Fluor 350 IF (p)   100 μL Log in to see 14至21个工作日
$416.90
详细

引用最多的anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like 抗体

  1. Human Polyclonal ERCC6L Primary Antibody for WB - ABIN527207 : Laulier, Cheng, Stark: The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation. in Nucleic acids research 2011 (PubMed)
    Show all 6 Pubmed References

  2. Human Monoclonal ERCC6L Primary Antibody for ELISA, WB - ABIN565778 : Leng, Bessuso, Jung, Wang, Qin: Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase. in Cell cycle (Georgetown, Tex.) 2008 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal ERCC6L Primary Antibody for WB - ABIN527205 : Nera, Huang, Lai, Xu: Elevated levels of TRF2 induce telomeric ultrafine anaphase bridges and rapid telomere deletions. in Nature communications 2015 (PubMed)

更多抗Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like的相互作用对抗体

Human Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) interaction partners

  1. These findings suggested that ERCC6L, which is highly expressed in breast cancer, acts as an oncogene, is involved in breast cancer development and may serve as a novel molecular target for the treatment of breast cancer.

  2. ERCC6L may stimulates cancer cell proliferation by promoting cell cycle through a way of RAB31-MAPK-CDK2, and it could be a potential biomarker for cancer prognosis and target for cancer treatment.

  3. Data indicate BEND3 as a new interaction partner for PICH in mitosis, and have defined the residues within a TPR-BEN domain interface that mediate this interaction.

  4. Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex has been reported.

  5. the mitotic roles of PICH and explore further the role of PICH in the timely segregation of the ribosomal DNA locus, are reported.

  6. a novel SUMO-dependent regulation of PICH's function on mitotic centromeres, is reported.

  7. PICH and Topo II cooperate to prevent chromosome missegregation events in mitosis.

  8. PICH is a SUMO-interacting protein and a mitotic SUMO substrate.

  9. PICH recognizes and stabilizes DNA under tension during anaphase, thereby facilitating the resolution of entangled sister chromatids.

  10. PICH protein was required for the correct recruitment to the centromere of active topoisomerase IIalpha, an enzyme specialized in the catenation/decatenation process.

  11. PICH binds to BLM and enables BLM localization to anaphase centromeric threads. PICH and BLM unravel centromeric chromatin and keep anaphase DNA threads mostly free of nucleosomes.

  12. the PICH-Plk1 complex plays a critical role in maintaining prometaphase chromosome architecture

  13. the spindle checkpoint failure formerly attributed to the depletion of PICH most likely reflects an off-target effect that causes the lowering of Mad2 transcript and protein.

  14. These data identify PICH as a novel essential component of checkpoint signaling.

  15. The sensitivity to depletion of topo IIalpha might be linked to structural alterations within the centromere domain, indicated by shortening of the distance across metaphase sister centromeres and persistence of PICH-coated connections.

  16. PICH phosphorylation and its ATPase activity are required for mitotic chromosome compaction through the targeting of Plk1 to chromosome arms.

  17. Functional characterization of the mouse Ercc6l ortholog.

Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) 抗原简介

蛋白简介

DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

Gene names and symbols associated with ERCC6L

  • ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L) 抗体
  • excision repair cross-complementing rodent repair deficiency complementation group 6 like (Ercc6l) 抗体
  • ERCC excision repair 6 like, spindle assembly checkpoint helicase (Ercc6l) 抗体
  • DNA excision repair protein ERCC-6-like (LOC100373376) 抗体
  • DNA excision repair protein ERCC-6-like (LOC100494766) 抗体
  • DNA excision repair protein ERCC-6-like (LOC100552957) 抗体
  • DNA excision repair protein ERCC-6-like (LOC100560751) 抗体
  • DNA excision repair protein ERCC-6-like (LOC100563247) 抗体
  • excision repair cross-complementation group 6-like (ercc6l) 抗体
  • BC004701 抗体
  • D330021P09Rik 抗体
  • fc22h03 抗体
  • PICH 抗体
  • RAD26L 抗体
  • RGD1565734 抗体
  • si:ch211-278b8.3 抗体
  • wu:fc22h03 抗体

Protein level used designations for ERCC6L

ATP-dependent helicase ERCC6-like , DNA excision repair protein ERCC-6-like , Plk1-interacting checkpoint helicase , SNF2/RAD54 family protein , excision repair cross-complementing rodent repair deficiency complementation group 6 - like , excision repair protein ERCC6-like , tumor antigen BJ-HCC-15 , excision repair cross-complementing rodent repair deficiency complementation group 6-like , excision repair cross-complementing rodent repair deficiency, complementation group 6-like

GENE ID SPECIES
54821 Homo sapiens
236930 Mus musculus
317252 Rattus norvegicus
782916 Bos taurus
100020004 Monodelphis domestica
100373376 Saccoglossus kowalevskii
100432874 Pongo abelii
100479265 Ailuropoda melanoleuca
100494766 Xenopus (Silurana) tropicalis
100552957 Anolis carolinensis
100560751 Anolis carolinensis
100563247 Anolis carolinensis
100584141 Nomascus leucogenys
100622071 Sus scrofa
100052221 Equus caballus
100005291 Danio rerio
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