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Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.. 再加上，我们可以发Elongation Factor RNA Polymerase II 抗体 (95) 和 和数多这个蛋白质的别的产品。
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ELL (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 (显示 THBS1 蛋白) regulation
The results indicate that p53 interferes with the interaction between ELL/EAF and ICE1 and represses transcription of small nuclear RNA genes by Pol II.
This work reveals a previously unrecognized function for ELL as an E3 ubiquitin ligase (显示 MUL1 蛋白) for c-Myc (显示 MYC 蛋白) and a potential tumour suppressor.
The Tax (显示 CNTN2 蛋白) oncogene (显示 RAB1A 蛋白) enhances ELL incorporation into p300 (显示 EP300 蛋白) and P-TEFb (显示 CCNT1 蛋白) containing protein complexes to activate transcription.
eleven-nineteen lysine-rich leukemia protein enhanced E2F1 (显示 E2F1 蛋白) deacetylation via recruitment of histone deacetylase 1 (显示 HDAC1 蛋白)
ELL is an essential player for RNA Pol II restart during cellular DNA damage response.
Studies indicate that the super elongation complex (SEC) consisting of ELL, P-TEFb (CDK9) and MLL required for rapid transcriptional induction in the presence or absence of paused RNA polymerase II (Pol II).
ELL has an early and essential role during rapid high-amplitude gene expression that is required for both Pol II pause site entry and release
Our findings suggest that ELL and HIF-1alpha (显示 HIF1A 蛋白) are binding partners and can modulate the functions of each other in hypoxia.
In the Acute Myeloid Leukemia (显示 BCL11A 蛋白) patients, detected MLL (显示 MLL 蛋白) rearrangements consisting of MLL (显示 MLL 蛋白)/AF6, MLL (显示 MLL 蛋白)/AF9 (显示 MLLT3 蛋白), MLL (显示 MLL 蛋白)/AF17 , MLL (显示 MLL 蛋白)/ELL and MLL (显示 MLL 蛋白) partial tandem duplication. MLL (显示 MLL 蛋白) rearrangement include chromosome translocation and partial tandem duplication.
Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.
RNA polymerase II elongation factor ELL
, ELL gene (11-19 lysine-rich leukemia gene)
, eleven-nineteen lysine-rich leukemia protein
, protein phosphatase 1, regulatory subunit 68
, RNA POLYMERASE II ELONGATION FACTOR ELL (ELEVEN-NINETEEN LYSINE-RICH LEUKEMIA PROTEIN)