Elastin Microfibril Interfacer 1 蛋白 (EMILIN1)

EMILIN1 encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. 再加上,我们可以发Emilin1 抗体 (52)Emilin1 试剂盒 (44)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
EMILIN1 298845  
EMILIN1 100952 Q99K41
EMILIN1 11117 Q9Y6C2
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,984.89
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
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大肠杆菌(E. Coli) 小鼠 His tag,T7 tag 100 μg Log in to see 15至18个工作日
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大肠杆菌(E. Coli) His-GST 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB) serum and peptide fingerprinting by MALDI-TOF-TOF mass spectrometry 50 μg Log in to see 6至9个工作日
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
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大肠杆菌(E. Coli) 大鼠 His tag,T7 tag 100 μg Log in to see 15至18个工作日
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大肠杆菌(E. Coli) His tag,T7 tag 100 μg Log in to see 15至18个工作日
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EMILIN1 蛋白 by Origin and Source

Origin 在表达 标记
Rat (Rattus)

Mouse (Murine) ,
,
Human , ,
, , ,

更多Elastin Microfibril Interfacer 1 (EMILIN1)互动伙伴

Zebrafish Elastin Microfibril Interfacer 1 (EMILIN1) interaction partners

  1. Expression of certain emilin genes in peculiar areas, such as the central nervous system or the posterior notochord, suggests that they may play a role in key morphogenetic processes:[Emilin]

Mouse (Murine) Elastin Microfibril Interfacer 1 (EMILIN1) interaction partners

  1. Data suggested mechanisms for homo- and hetero-typic EMILINs multimers formation: EMILIN1 or EMILIN2 (显示 EMILIN2 蛋白) alone can form trimers and multimers in the absence of each other or they can co-polymerize in a head-to-tail fashion to form hetero-typic multimers.

  2. Emilin1 deficiency results in aortic valve disease, mediated by non-canonical (MAPK (显示 MAPK1 蛋白)/phosphorylated Erk1 (显示 MAPK3 蛋白) and Erk2 (显示 MAPK1 蛋白)) TGF-beta (显示 TGFB1 蛋白) dysregulation.

  3. EMILIN1/integrin alpha 9 beta 1 interaction contributes to lymphatic valve formation, maintenance, and function.

  4. these data established that EMILIN1 exerts a protective role in tumor growth, in tumor lymphatic vessel formation, as well as in metastatic spread to lymph nodes

  5. Emilin-1 produced by vascular smooth muscle cells acts as a main regulator of resting blood pressure levels by controlling the myogenic response in resistance arteries through TGF-beta (显示 TGFB1 蛋白).

  6. Pull-down assays indicated that the binding to organ of Corti CNGA3 (显示 CNGA3 蛋白) was attributable to the EMILIN1 intracellular sequence that follows a predicted transmembrane domain in the C-terminus

  7. EMILIN1 is identified as a novel ligand for keratinocyte alpha9beta1 integrin, suggesting prospective roles for this receptor-ligand pair in skin homeostasis.

  8. EMILIN1 is a novel local regulator of lymphangiogenesis

Human Elastin Microfibril Interfacer 1 (EMILIN1) interaction partners

  1. This study is the first to identify EMILIN-1 and ILK (显示 ILK 蛋白) as prospective markers of islet regenerative function in human mesenchymal stem cells.

  2. These findings collectively suggest that EMILIN1 may represent a new disease gene associated with an autosomal-dominant connective tissue disorder.

  3. Data suggested mechanisms for homo- and hetero-typic EMILINs multimers formation: EMILIN1 or EMILIN2 (显示 EMILIN2 蛋白) alone can form trimers and multimers in the absence of each other or they can co-polymerize in a head-to-tail fashion to form hetero-typic multimers.

  4. The present findings highlight the peculiar activity of PMN elastase (显示 ELANE 蛋白) in disabling EMILIN1 suppressor function.

  5. All three SNPs in introns 1 and 5 (rs2289360, rs2011616 and rs7424556) of EMILIN1 were in strong pair-wise linkage disequilibrium and were significantly associated with hypertension.

  6. Emilin-1 produced by vascular smooth muscle cells acts as a main regulator of resting blood pressure levels by controlling the myogenic response in resistance arteries through TGF-beta (显示 TGFB1 蛋白).

  7. There were significant associations of rs2011616 and rs2304682 polymorphisms in the EMILIN1 gene with hypertension among Japanese.

  8. EMILIN-1 may regulate the formation of oxytalan fibers and play a role in their homeostasis.

  9. rs2289360, rs2011616, and rs2304682 in the human EMILIN1 gene, as well as the haplotype constructed using rs2536512, rs2011616, and rs17881426, are useful genetic markers of essential hypertension in Japanese men.

  10. NMR assignments for the C-terminal globular domain of EMILIN-1

蛋白简介Emilin1 (EMILIN1)

蛋白简介

This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung.

Gene names and symbols associated with EMILIN1

  • elastin microfibril interfacer 1 (Emilin1)
  • elastin microfibril interfacer 1a (emilin1a)
  • elastin microfibril interfacer 1b (emilin1b)
  • elastin microfibril interfacer 1 (EMILIN1)
  • elastin microfibril interfacer 1 L homeolog (emilin1.L)
  • 5830419M17Rik 蛋白
  • AW229038 蛋白
  • BB105748 蛋白
  • EMI 蛋白
  • EMILIN 蛋白
  • EMILIN-1 蛋白
  • EMILIN1 蛋白
  • gp115 蛋白
  • im:7159005 蛋白
  • si:dkey-20n10.2 蛋白
  • wu:fc16f07 蛋白
  • zgc:136949 蛋白

Protein level used designations for EMILIN1

EMILIN-1 , fc16f07 , elastin microfibril interfacer 1 , EMILIN-1-like , elastin microfibril interface located protein 1 , elastin microfibril interface-located protein 1 , elastin microfibril interface located protein

GENE ID SPECIES
298845 Rattus norvegicus
566473 Danio rerio
751598 Danio rerio
459093 Pan troglodytes
475696 Canis lupus familiaris
698204 Macaca mulatta
733171 Xenopus laevis
100030962 Monodelphis domestica
100447513 Pongo abelii
100523665 Sus scrofa
100600285 Nomascus leucogenys
100952 Mus musculus
11117 Homo sapiens
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