Ectonucleoside Triphosphate diphosphohydrolase 5 蛋白 (ENTPD5)

The protein encoded by ENTPD5 is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. 再加上,我们可以发Ectonucleoside Triphosphate diphosphohydrolase 5 抗体 (66)Ectonucleoside Triphosphate diphosphohydrolase 5 试剂盒 (11)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
ENTPD5 957 O75356
ENTPD5 12499 Q9WUZ9
大鼠 ENTPD5 ENTPD5 314312 Q6P6S9
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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Baculovirus infected Insect Cells 小鼠 His tag 10 μg Log in to see 20至21个工作日
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
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ENTPD5 蛋白 by Origin and Source

Origin 在表达 标记
Human , , ,
, ,
Mouse (Murine) ,

更多Ectonucleoside Triphosphate diphosphohydrolase 5 (ENTPD5)互动伙伴

Human Ectonucleoside Triphosphate diphosphohydrolase 5 (ENTPD5) interaction partners

  1. ENTPD5 is a mediator of mutant p53 (显示 TP53 蛋白) gain of function activity in clonogenic growth, architectural tissue remodeling, migration, invasion, and lung colonization in lung cancer and its mouse models

  2. Results suggest that ENTPD5 affects lung cancer apoptosis via Caspase 3 (显示 CASP3 蛋白) pathway, and can be potentially used to monitor prognosis or to guide appropriate therapeutic regimens.

  3. The main point of this review is to integrate the findings and proposed theories about the role played by NTPDase5/mt-PCPH in cancer progression, considering that these proteins have been suggested as potential early diagnostic tools and therapy targets.

  4. These results strongly suggest that the mt-PCPH ( ENTPD5)oncoprotein may regulate the cellular energy levels and subsequent chemoresistance by an NTPDase-independent mechanism

  5. Upregulation of ENTPD5 is associated with altered metabolism in gliomablastoma multiforme.

  6. The elevation of ENTPD5 activity therefore protects AKT (显示 AKT1 蛋白)-active cancer cells from protein-overloading-induced endoplasmic reticulum stress and the resulting growth arrest and apoptosis.

  7. Study reports that ENTPD5, an endoplasmic reticulum (ER) enzyme, is upregulated in cell lines and primary human (显示 AKT1 蛋白)tumor samples with active AKT.

  8. deregulation and loss of expression in the progression of laryngeal neoplasia [PCPH]

  9. Results positively identify PCPH as a good early molecular marker for testicular neoplasms, and strongly indicate that immunodetection of truncated PCPH polypeptides may be a useful diagnostic tool for testicular germ cell tumors.

  10. PCPH/ENTPD5 expression enhances the invasiveness of human prostate cancer cells by a protein kinase C delta (显示 PKCd 蛋白)-dependent mechanism

Mouse (Murine) Ectonucleoside Triphosphate diphosphohydrolase 5 (ENTPD5) interaction partners

  1. Six proteins were regulated at both basal and inducible levels exhibiting the largest dynamic range of Nrf2 (显示 NFE2L2 蛋白) regulation: cytochrome CYP2A5, GSTM3 (显示 GSTM3 蛋白), GSTM1 (显示 GSTM1 蛋白), ENTPD5,UDPGDH (显示 UGDH 蛋白), and EPHX1 (显示 EPHX1 蛋白).

  2. During a study using the embryonic fibroblasts from the PTEN null mice ENTPD5, is found to be upregulated by AKT (显示 AKT1 蛋白) activation; this enzyme seems to mediate many of the observed cancer-related phenotypes associated with AKT (显示 AKT1 蛋白) activation.

  3. The effect of Entpd5 deletion on the development of hepatocellualr neoplasia in mice is reported.

蛋白简介Ectonucleoside Triphosphate diphosphohydrolase 5 (ENTPD5)

蛋白简介

The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases.

Gene names and symbols associated with ENTPD5

  • ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5)
  • ectonucleoside triphosphate diphosphohydrolase 5 (entpd5)
  • ectonucleoside triphosphate diphosphohydrolase 5 L homeolog (entpd5.L)
  • ectonucleoside triphosphate diphosphohydrolase 5 (Entpd5)
  • AI196558 蛋白
  • AI987697 蛋白
  • Cd39l4 蛋白
  • cph 蛋白
  • ENTPD5 蛋白
  • ER-UDPase 蛋白
  • mNTPase 蛋白
  • NTPDase-5 蛋白
  • NTPDase5 蛋白
  • Pcph 蛋白

Protein level used designations for ENTPD5

ectonucleoside triphosphate diphosphohydrolase 5 , NTPDase5 , ecto-nucleosidase triphosphate diphosphohydrolase 5 , CD39 antigen-like 4 , CD39-like 4 , ER-UDPase , GDPase ENTPD5 , NTPDase 5 , Pcph proto-oncogene protein , UDPase ENTPD5 , guanosine-diphosphatase ENTPD5 , nucleoside diphosphatase , proto-oncogene CPH , uridine-diphosphatase ENTPD5 , Guanosine-diphosphatase ENTPD5 , Nucleoside diphosphatase , Proto-oncogene cph , Uridine-diphosphatase ENTPD5 , cph oncogene product , cph proto-oncogene product

GENE ID SPECIES
453027 Pan troglodytes
480384 Canis lupus familiaris
677734 Xenopus (Silurana) tropicalis
698503 Macaca mulatta
734189 Xenopus laevis
100220000 Taeniopygia guttata
100341814 Oryctolagus cuniculus
957 Homo sapiens
12499 Mus musculus
314312 Rattus norvegicus
533096 Bos taurus
423343 Gallus gallus
100470325 Ailuropoda melanoleuca
101836947 Mesocricetus auratus
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