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ESF1 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. 再加上，我们可以发ESF1, Nucleolar Pre-RRNA Processing Protein, Homolog (S. Cerevisiae) 试剂盒 (6) 和 和数多这个蛋白质的别的产品。
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Pathogenic missense mutation in SOX3 (显示 SOX3 抗体) gene is associated with intellectual disability, microphthalmia, coloboma, hypopituitarism, facial dysmorphology and dental anomalies, including microcephaly, retrognathia and a solitary median maxillary central incisor amongst other features.
our data indicate that SOX3 (显示 SOX3 抗体) may serve as an oncogene (显示 RAB1A 抗体) in osteosarcoma
deletion of the SOX3 (显示 SOX3 抗体) gene may have a role in intellectual disability with hemophilia B
Results show that SOX3 (显示 SOX3 抗体) is upregulated in human osteosarcoma (OS) tissues and provide evidence that SOX3 (显示 SOX3 抗体) promotes migration, invasiveness, and EMT (显示 ITK 抗体) in OS cells via transcriptional activation of Snail1 (显示 SNAI1 抗体) expression.
we provide a first map of the epigenetic landscape of SOX3 in pluripotent cells and during the early phases of neural differentiation. We found SOX3 gene to be non methylated from undifferentiated NT2/D1 to cells committed towards neural lineage.
These findings demonstrate the novel mechanism by which Sox3 contributes to endometrial cancer stem cell invasion and suggest that repression of Sox3 by microRNA-194 may have therapeutic potential to suppress endometrial carcinoma metastasis. The cancer stem cell marker, CD133, might be the surface marker of endometrial cancer stem cell.
Data indicate that SRY-box 3 transcription factor SOX-3 (显示 SOX3 抗体) targets Src kinase (显示 CSK 抗体) in epithelial ovarian cancer (EOC) cells.
SOX3 (显示 SOX3 抗体) overdosage permits normal sex development in 46,XX individuals with random X inactivation.
Translocations interrupting this region may also affect the gonadal development, possibly depending on the chromatin context of the recipient chromosome. SOX3 (显示 SOX3 抗体) duplications may substitute SRY (显示 SRY 抗体) in some XX subjects
Screening for SOX3 (显示 SOX3 抗体) should be advised not only for hypopituitary patients with an ectopic posterior pituitary, but also for those with a structurally normal pituitary
The Rattus rattus ABT1-associated protein formed a complex with ABT1 (显示 Abt1 抗体) and suppressed activation of Pol II (显示 0 抗体)-directed transcription in mammalian cells. It binds and negatively regulates ABT1 (显示 Abt1 抗体).
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.
, ESF1 homolog