ELMO/CED-12 Domain Containing 1 蛋白 (ELMOD1)

Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family (By similarity). 再加上,我们可以发ELMO/CED-12 Domain Containing 1 抗体 (33)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
大鼠 ELMOD1 ELMOD1 315670  
ELMOD1 55531 Q8N336
ELMOD1 270162 Q3V1U8
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
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酵母菌 Orang-Utan His tag   1 mg Log in to see 60至71个工作日
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酵母菌 Cow His tag   1 mg Log in to see 60至71个工作日
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ELMOD1 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,
Mouse (Murine)

更多ELMO/CED-12 Domain Containing 1 (ELMOD1)互动伙伴

Human ELMO/CED-12 Domain Containing 1 (ELMOD1) interaction partners

  1. Data suggest that GPR124 promotes cell adhesion via interaction with Elmo1 (显示 ELMO1 蛋白)-Dock180 (显示 DOCK1 蛋白) and intersectin 1 (显示 ITSN1 蛋白)/2; this constitutes a previously unrecognized heteromeric complex that is putatively involved in GPR124-dependent adhesive/angiogenic responses in vascular endothelial cells. (GPR124 = G-protein coupled receptor 124; Elmo1 (显示 ELMO1 蛋白) = ELMO domain-containing protein 1; Dock180 (显示 DOCK1 蛋白) = dedicator of cytokinesis protein 1 (显示 DOCK1 蛋白) 180 kDa)

  2. The non-opioid sigma-1 receptor (S1R) was identified as a novel effector of GAP activity of ELMOD1-3 proteins as its direct binding to either ELMOD1 or ELMOD2 (显示 ELMOD2 蛋白) resulted in loss of GAP activity.

Mouse (Murine) ELMO/CED-12 Domain Containing 1 (ELMOD1) interaction partners

  1. Elmod1 has relatively high and selective expression in the brain but as of 2014 has not been well-studied with respect to CNS function or disease associations. It is part of the core brain ignorome. Elmod1 has a high cis (显示 CISH 蛋白)-eQTL (显示 EQTN 蛋白) in hippocampus, hypothalamus, striatum. Hearing sensitivity trait in GeneNetwork.org also maps to the region containing Elmod1.

  2. This finding connecting ELMOD1 deficiencies with stereocilia dysmorphologies establishes a link between the Ras superfamily of small regulatory GTPases and the actin cytoskeleton dynamics of hair cell stereocilia.

蛋白简介ELMO/CED-12 Domain Containing 1 (ELMOD1)

蛋白简介

Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family (By similarity).

Gene names and symbols associated with ELMOD1

  • ELMO domain containing 1 (Elmod1)
  • ELMO domain containing 1 (ELMOD1)
  • ELMO/CED-12 domain containing 1 (Elmod1)
  • 4831417L10 蛋白
  • AI428506 蛋白
  • AI834991 蛋白
  • RGD1564186 蛋白

Protein level used designations for ELMOD1

ELMO domain containing 1 , ELMO domain-containing protein 1

GENE ID SPECIES
315670 Rattus norvegicus
55531 Homo sapiens
270162 Mus musculus
768233 Bos taurus
100174164 Pongo abelii
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