anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) 抗体

Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. 再加上,我们可以发EF-Hand Calcium Binding Domain 4B 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
EFCAB4B 84766 Q9BSW2
EFCAB4B 381812 Q3UP38
EFCAB4B    
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Showing 10 out of 54 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-EFCAB4B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  NCI-H226 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-EFCAB4B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  NCI-H226 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: EFCAB4B Antibody [NBP1-82687] Staining of human cell line A-431 shows positivity in nucleus, nucleoli, cytoplasm & golgi apparatus. Immunohistochemistry-Paraffin: EFCAB4B Antibody [NBP1-82687] - Staining of human stomach shows strong cytoplasmic, membranous and nuclear positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日
$494.38
详细
非结合性 WB EFCAB4B Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the EFCAB4B antibody detected the EFCAB4B protein (arrow). 400 μL Log in to see 10至11个工作日
$385.00
详细
非结合性 EIA, WB   0.1 mg Log in to see 4至8个工作日
$522.50
详细
非结合性 ELISA, IHC, IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.05 mg Log in to see 11至14个工作日
$484.00
详细
小鼠 非结合性 IF, WB Western Blot analysis of EFCAB4B expression in transfected 293T cell line by EFCAB4B MaxPab polyclonal antibody.Lane 1: MGC4266 transfected lysate(43.45 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to EFCAB4B on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Log in to see 11至12个工作日
$440.00
详细
非结合性 WB Western Blot: EFCAB4B Antibody [NBP1-55340] - Titration: 0.2-1 ug/ml, Positive Control: NCI-H226 cell lysate. 100 μL Log in to see 8至11个工作日
$488.73
详细
非结合性 WB EFCAB4B antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9至11个工作日
$473.93
详细
非结合性 WB EFCAB4B antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9至11个工作日
$473.93
详细

更多抗EF-Hand Calcium Binding Domain 4B的相互作用对抗体

Human EF-Hand Calcium Binding Domain 4B (EFCAB4B) interaction partners

  1. There is a significant association between the EFCAB4B gene and localized periodontitis.

  2. Results show the characterization of CRACR2A protein which encodes a large Rab GTPase containing multiple functional domains contrary to small Rab GTPases. It was found to play an unexpected role in regulating intracellular signaling pathways important for T cell activation.

  3. GTP binding and prenylation of CRACR2A were associated with its localization near the Golgi and its stability

  4. endothelial cells contain a long variant of CRACR2A which is an EF-hand-containing Rab protein that lacks impact on CRAC channels

  5. CRACR2A interacts directly with Orai1 and STIM1, forming a ternary complex that dissociates at elevated Ca(2+) concentrations; is a key regulator of CRAC channel-mediated SOCE

Mouse (Murine) EF-Hand Calcium Binding Domain 4B (EFCAB4B) interaction partners

  1. GTP binding and prenylation of CRACR2A were associated with its localization near the Golgi and its stability

EF-Hand Calcium Binding Domain 4B (EFCAB4B) 抗原简介

蛋白简介

Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex (By similarity).

Gene names and symbols associated with EFCAB4B

  • calcium release activated channel regulator 2A (CRACR2A) 抗体
  • calcium release activated channel regulator 2A (Cracr2a) 抗体
  • CRACR2A 抗体
  • Gm462 抗体
  • Gm1073 抗体

Protein level used designations for EFCAB4B

CRAC channel regulator 2A , EF-hand calcium-binding domain-containing protein 4B , calcium release-activated calcium channel regulator 2A

GENE ID SPECIES
84766 Homo sapiens
381812 Mus musculus
anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) 抗体 精选生产商
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