anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) 抗体

Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. 再加上,我们可以发和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
EFCAB4B 84766 Q9BSW2
EFCAB4B 381812 Q3UP38
EFCAB4B    
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Showing 10 out of 53 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-EFCAB4B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  NCI-H226 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-EFCAB4B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  NCI-H226 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: EFCAB4B Antibody [NBP1-82687] Staining of human cell line A-431 shows positivity in nucleus, nucleoli, cytoplasm & golgi apparatus. Immunohistochemistry-Paraffin: EFCAB4B Antibody [NBP1-82687] - Staining of human stomach shows strong cytoplasmic, membranous and nuclear positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
Cow 非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 WB EFCAB4B Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the EFCAB4B antibody detected the EFCAB4B protein (arrow). 400 μL Log in to see 10至11个工作日
$335.50
详细
非结合性 EIA, WB   0.1 mg Log in to see 8至11个工作日
$474.10
详细
非结合性 ELISA, IHC, IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11至14个工作日
$484.00
详细
小鼠 非结合性 IF, WB Western Blot analysis of EFCAB4B expression in transfected 293T cell line by EFCAB4B MaxPab polyclonal antibody.<br><br>Lane 1: MGC4266 transfected lysate(43.45 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to EFCAB4B on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Log in to see 11至12个工作日
$440.00
详细
非结合性 WB Western Blot: EFCAB4B Antibody [NBP1-55340] - Titration: 0.2-1 ug/ml, Positive Control: NCI-H226 cell lysate. 100 μL Log in to see 8至11个工作日
$485.88
详细

更多抗EF-Hand Calcium Binding Domain 4B的相互作用对抗体

Human EF-Hand Calcium Binding Domain 4B (EFCAB4B) interaction partners

  1. Results show the characterization of CRACR2A protein which encodes a large Rab GTPase (显示 RAB6A 抗体) containing multiple functional domains contrary to small Rab (显示 HRB 抗体) GTPases. It was found to play an unexpected role in regulating intracellular signaling pathways important for T cell activation.

  2. GTP binding (显示 RND2 抗体) and prenylation of CRACR2A were associated with its localization near the Golgi and its stability

  3. endothelial cells contain a long variant of CRACR2A which is an EF-hand-containing Rab (显示 HRB 抗体) protein that lacks impact on CRAC channels

  4. CRACR2A interacts directly with Orai1 (显示 ORAI1 抗体) and STIM1 (显示 STIM1 抗体), forming a ternary complex that dissociates at elevated Ca(2 (显示 CA2 抗体)+) concentrations; is a key regulator of CRAC channel-mediated SOCE

Mouse (Murine) EF-Hand Calcium Binding Domain 4B (EFCAB4B) interaction partners

  1. GTP binding (显示 RND2 抗体) and prenylation of CRACR2A (显示 EFCAB4A 抗体) were associated with its localization near the Golgi and its stability

EF-Hand Calcium Binding Domain 4B (EFCAB4B) 抗原简介

蛋白简介

Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex (By similarity).

Gene names and symbols associated with EFCAB4B

  • calcium release activated channel regulator 2A (CRACR2A) 抗体
  • calcium release activated channel regulator 2A (Cracr2a) 抗体
  • CRACR2A 抗体
  • Gm462 抗体
  • Gm1073 抗体

Protein level used designations for EFCAB4B

CRAC channel regulator 2A , EF-hand calcium-binding domain-containing protein 4B , calcium release-activated calcium channel regulator 2A

GENE ID SPECIES
84766 Homo sapiens
381812 Mus musculus
anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) 抗体 精选生产商
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