Dystrobrevin, beta 蛋白 (DTNB)

DTNB encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). 再加上,我们可以发Dystrobrevin beta 抗体 (80)Dystrobrevin beta 试剂盒 (5)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
DTNB 1838 O60941
DTNB 362715 P84060
DTNB 13528 O70585
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
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DTNB 蛋白 by Origin and Source

Origin 在表达 标记
Human , , ,
, , ,
Rat (Rattus)

Mouse (Murine)

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Human Dystrobrevin, beta (DTNB) interaction partners

  1. Data provide new insights into the role of beta-dystrobrevin in the molecular mechanisms underlying neuronal differentiation that could be relevant in the establishment of the cognitive impairment in Duchene muscular dystrophy.

  2. beta-dystrobrevin interacts with the HMG20 (显示 UBC 蛋白) proteins iBRAF (显示 HMG20A 蛋白) and BRAF35 (显示 HMG20B 蛋白)

  3. results suggest that dysbindin (显示 DTNBP1 蛋白) assembled into BLOC-1 (显示 BLOC1S1 蛋白) is not a physiological binding partner of the dystrobrevins, likely due to engagement of its dystrobrevin (显示 DTNA 蛋白)-binding region in interactions with other subunits

Zebrafish Dystrobrevin, beta (DTNB) interaction partners

  1. Dystrobrevin family gene expression in zebrafish is reported.

Mouse (Murine) Dystrobrevin, beta (DTNB) interaction partners

  1. beta-dystrobrevin interacts with the HMG20 (显示 UBC 蛋白) proteins iBRAF (显示 HMG20A 蛋白) and BRAF35 (显示 HMG20B 蛋白)

  2. a novel function for dystrobrevin (显示 DTNA 蛋白) as a motor protein receptor that might play a major role in the transport of components of the dystrophin (显示 DMD 蛋白)-associated protein complex to specific sites in the cell

  3. kinetics of the dystrobrevin-Kif5A interaction showed a lower affinity of alpha compared to that of beta-dystrobrevin for binding to kinesin

  4. AlphaDB, betaDB, & dystrophin (显示 DMD 蛋白) are concentrated at a discrete subset of inhibitory synapses on the somata & dendrites of cerebellar Purkinje cells. Sensorimotor behaviors reflecting cerebellar function are perturbed in mice lacking any of these proteins.

  5. biglycan (显示 BGN 蛋白) is important for the maintenance of muscle cell integrity and plays a direct role in regulating the expression and sarcolemmal localization of the intracellular signaling proteins dystrobrevin-1 and -2, alpha- and beta1-syntrophin (显示 SNTB1 蛋白) and nNOS (显示 NOS1 蛋白)

蛋白简介Dystrobrevin beta (DTNB)

蛋白简介

This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with Dystrobrevin, beta 蛋白 (DTNB)

  • dystrobrevin beta (DTNB)
  • dystrobrevin, beta b (dtnbb)
  • dystrobrevin, beta (Dtnb)
  • dystrobrevin, beta a (dtnba)
  • dystrobrevin beta (dtnb)
  • dystrobrevin beta (Dtnb)
  • bdtn 蛋白
  • btnb 蛋白
  • dtnb 蛋白
  • dtng 蛋白
  • GDTN 蛋白
  • gtnb 蛋白
  • wu:fc61h11 蛋白

Protein level used designations for Dystrobrevin, beta 蛋白 (DTNB)

DTN-B , beta-dystrobrevin , dystrobrevin beta , dystrobrevin, beta , dystrobrevin, gamma , gamma-dystrobrevin , mDTN-B , dystrobrevin beta-like , LOW QUALITY PROTEIN: dystrobrevin beta

GENE ID SPECIES
1838 Homo sapiens
482997 Canis lupus familiaris
534119 Bos taurus
459076 Pan troglodytes
421992 Gallus gallus
559786 Danio rerio
362715 Rattus norvegicus
325242 Danio rerio
100055834 Equus caballus
13528 Mus musculus
696167 Macaca mulatta
100412654 Callithrix jacchus
100481157 Ailuropoda melanoleuca
100496192 Xenopus (Silurana) tropicalis
100515309 Sus scrofa
100548999 Meleagris gallopavo
100589073 Nomascus leucogenys
100721904 Cavia porcellus
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