Dynein, Light Chain, Roadblock Type 1 蛋白 (DYNLRB1)

DYNLRB1 is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. 再加上,我们可以发DYNLRB1 抗体 (12)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
DYNLRB1 67068 P62627
DYNLRB1 170714 P62628
DYNLRB1 83658 Q9NP97
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$5,465.26
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大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$5,465.26
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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大肠杆菌(E. Coli) His tag 50 μg Log in to see 15至19个工作日
$400.00
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酵母菌 大鼠 His tag   1 mg Log in to see 60至71个工作日
$2,159.67
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酵母菌 Cow His tag   1 mg Log in to see 60至71个工作日
$2,159.67
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大肠杆菌(E. Coli) His tag   1 mg Log in to see 2至3个工作日
$5,723.08
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DYNLRB1 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine)

Rat (Rattus)

Human , ,
, ,

更多Dynein, Light Chain, Roadblock Type 1 (DYNLRB1)互动伙伴

Mouse (Murine) Dynein, Light Chain, Roadblock Type 1 (DYNLRB1) interaction partners

  1. The presence of an N-terminal tag on dynein light-chain Roadblock/LC7 affects its interaction with a functional partner.

Human Dynein, Light Chain, Roadblock Type 1 (DYNLRB1) interaction partners

  1. Human colorectal carcinoma cells display decreased tumor progression and invasion when a novel anti-cell motility target, DYNLRB1, is being silenced.

  2. TGFbeta (显示 TGFB1 蛋白) regulates km23-1 interaction with the R1beta regulatory subunit of protein kinase A.

  3. these findings demonstrate that km23-1 regulates RhoA (显示 RHOA 蛋白) and motility-associated actin modulating proteins, suggesting that km23-1 may represent a novel target for anti-metastatic therapy.

  4. km23-1 is required for TGFbeta1 (显示 TGFB1 蛋白) autoinduction through Smad2 (显示 SMAD2 蛋白)-independent Ras/ERK (显示 EPHB2 蛋白)/JNK (显示 MAPK8 蛋白) pathways

  5. Silencing of km23, either through somatic genetic mutation or promoter hypermethylation, is rare in ovarian, breast, and colorectal cancers.

  6. report the 2.1-A crystal structure of Dnlc2A using single anomalous diffraction

  7. DYNLRB1 specifically interacts with all three Rab6 isoforms and co-localises at the Golgi.

  8. Identification of dynein light chain road block-1 as a novel interaction partner with the human reduced folate carrier.

  9. Findings indicate that km23-2 (DYNLRB2 (显示 DYNLRB2 蛋白)) is required for Smad3 (显示 SMAD3 蛋白)-dependent TGFbeta (显示 TGFB1 蛋白) signaling. Km23-2 has functions in TGFbeta (显示 TGFB1 蛋白) signaling that are distinct from those for km23-1 (DYNLRB1).

蛋白简介DYNLRB1

蛋白简介

This gene is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression.

Gene names and symbols associated with DYNLRB1

  • dynein light chain roadblock-type 1 (Dynlrb1)
  • dynein light chain roadblock-type 1 (DYNLRB1)
  • 2010012N15Rik 蛋白
  • 2010320M17Rik 蛋白
  • 9430076K19Rik 蛋白
  • AV124457 蛋白
  • BITH 蛋白
  • BLP 蛋白
  • DNCL2A 蛋白
  • DNLC2A 蛋白
  • km23 蛋白
  • km23-1 蛋白
  • ROBLD1 蛋白

Protein level used designations for DYNLRB1

dynein light chain 2A, cytoplasmic , dynein, cytoplasmic, light chain 2A , dynein, cytoplasmic, light polypeptide 2A , BLP , bithoraxoid-like protein , dynein-associated protein Km23 , dynein-associated protein RKM23 , robl/LC7-like protein , ROBL/LC7-like 1 , dynein light chain roadblock-type 1 , roadblock domain-containing protein 1

GENE ID SPECIES
67068 Mus musculus
170714 Rattus norvegicus
83658 Homo sapiens
513342 Bos taurus
DYNLRB1 蛋白 (DYNLRB1) 精选生产商
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