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May be involved in the maintenance of active epigenetic status of target genes (By similarity). 再加上，我们可以发Developmental Pluripotency Associated 4 抗体 (81) 和 Developmental Pluripotency Associated 4 蛋白 (6)和数多这个蛋白质的别的产品。
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knockdown of PCGF1 (显示 PCGF1 ELISA试剂盒) results in reduced expression of DPPA4 and other subunits of the variant PRC1 (显示 PRC1 ELISA试剂盒) complex at both mRNA and protein levels
Results identified a new family of pluripotency-related oncogenes consisting of DPPA2 and DPPA4.
Thsi study identifies DPPA4 and other genes as putative Sox2 (显示 SOX2 ELISA试剂盒):Oct-3/4 (显示 POU5F1 ELISA试剂盒) target genes using a combination of in silico analysis and transcription-based assays.
Results have identified a new family of pluripotency-related oncogenes consisting of DPPA2 and DPPA4.
Study of expression and function of pluripotent markers such as Dppa2 and Dppa4 is likely to unveil new aspects of the regulation of pluripotency and germ line development in mammals.
DPPA4 is a nuclear factor associated with active chromatin
Dppa4 is completely dispensable for ES cell identity and germ cell development. Instead, loss of Dppa4 in mice results in late embryonic/perinatal death and striking skeletal defects with partial penetrance.
May be involved in the maintenance of active epigenetic status of target genes (By similarity). May inhibit differentiation of embryonic cells into a primitive ectoderm lineage (By similarity).
developmental pluripotency-associated protein 4
, embryonic stem cell-associated transcript 15-1 protein
, developmental pluripotency associated 4
, putative dipeptides/oligopeptides ABC transporter periplasmic substrate-binding protein
, dipeptide ABC transport system, substrate-binding protein