anti-Deleted in Azoospermia-Like (DAZL) 抗体

The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. 再加上,我们可以发DAZL 蛋白 (11)DAZL 试剂盒 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
DAZL 1618 Q92904
DAZL 680486  
DAZL 13164 Q64368
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antibodies-online.cn销售最多的anti-DAZL 抗体

Showing 10 out of 96 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-DAZL Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  721_B cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB Host:  Rabbit  Target Name:  DAZL  Sample Type:  Stomach tumor lysates  Antibody Dilution:  1.0ug/ml Host:  Mouse  Target Name:  DAZL  Sample Tissue:  Mouse Brain  Antibody Dilution:  1ug/ml 100 μL Log in to see 2至3个工作日
$289.00
详细
山羊 非结合性 IHC, ELISA, WB ABIN185441 (0.1µg/ml) staining of human ovary lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6至7个工作日
$358.02
详细
山羊 非结合性 IHC (p), IHC, ELISA, WB ABIN250853 (0.1ug/ml) staining of Human Ovary lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Immunohistochemistry-Paraffin: DAZL Antibody [ABIN250853] - Stainingof paraffin embedded Mouse Testis. 0.1 mg Log in to see 7至9个工作日
$485.88
详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: DAZL Antibody [NBP1-85306] - Staining of human cell line A-431 shows positivity in cytoplasm. Western Blot: DAZL Antibody [NBP1-85306] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY400541) 0.1 mL Log in to see 10至13个工作日
$491.63
详细
Cow 山羊 非结合性 EIA, IHC (p), WB   0.1 mg Log in to see 8至11个工作日
$462.00
详细
非结合性 WB WB Image DAZL antibody detects DAZL protein by western blot analysis. Whole cell extracts (30 μg) and Mouse tissue extracts (50 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with DAZL antibody , diluted at a dilution of 1:1000. 100 μL Log in to see 1至2个工作日
$358.60
详细
非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
Cow 山羊 非结合性 ELISA, WB 100 μg Log in to see 7至9个工作日
$610.50
详细
非结合性 IHC, IHC (p), WB Immunohistochemistry-Paraffin: DAZL Antibody [NBP1-85307] - Staining of human testis shows distinct positivity in cells in seminiferus ducts. Western Blot: DAZL Antibody [NBP1-85307] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY400541) 0.1 mL Log in to see 10至13个工作日
$491.63
详细

引用最多的anti-DAZL 抗体

  1. Human Polyclonal DAZL Primary Antibody for IHC (p), IHC - ABIN250853 : Hermann, Sukhwani, Lin, Sheng, Tomko, Rodriguez, Shuttleworth, McFarland, Hobbs, Pandolfi, Schatten, Orwig: Characterization, cryopreservation, and ablation of spermatogonial stem cells in adult rhesus macaques. in Stem cells (Dayton, Ohio) 2007 (PubMed)
    Show all 7 Pubmed References

  2. Cynomolgus Monoclonal DAZL Primary Antibody for IF, IHC (p) - ABIN2473235 : Fabre, Bureau, Pouliquen, Lorans: Binding sites for human interleukin 1 alpha, gamma interferon and tumor necrosis factor on cultured fibroblasts of normal cornea and keratoconus. in Current eye research 1991 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal DAZL Primary Antibody for IF (p), IHC (p) - ABIN1385600 : Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable. in Chemosphere 2018 (PubMed)

  4. Human Polyclonal DAZL Primary Antibody for ICC, IF - ABIN4304346 : Djureinovic, Fagerberg, Hallström, Danielsson, Lindskog, Uhlén, Pontén: The human testis-specific proteome defined by transcriptomics and antibody-based profiling. in Molecular human reproduction 2014 (PubMed)

更多抗DAZL的相互作用对抗体

Human Deleted in Azoospermia-Like (DAZL) interaction partners

  1. computational analysis of free energy change due to this point mutation using GROMOS96 indicated decreased stability of the DAZL protein. The N109T variant in an infertile male population may provide a genetic marker for mutational analysis of DAZL

  2. Data suggest that DAZL may be one such factor in human female fertility

  3. Through the translational regulation of novel RNA targets SMC1B (显示 SMC1B 抗体) and TEX11 (显示 TEX11 抗体), DAZL may have a key role in regulating chromosome cohesion and DNA recombination; two processes fundamental in determining oocyte quality and whose establishment in foetal life may support lifelong fertility.

  4. hypermethylation of DAZL and BOULE (显示 BOLL 抗体) promoters in human sperm is associated with human infertility

  5. data can be used to further elucidate the role of NANOS3 (显示 NANOS3 抗体) and DAZL in germ cell development both in vitro and in vivo

  6. DAZL was not expressed either in normal cultures or lesions from cervixes with papillomavirus infections and cervical intraepithelial neoplasia.

  7. analysis demonstrated that SNP260 of DAZL did not contribute to oligo/azoospermia while SNP386 was correlated to male infertility

  8. Neither the A260G nor the A386G polymorphism of DAZL appeared to be involved in male infertility.

  9. demonstrate that Boll (显示 BOLL 抗体) is also transiently expressed during oogenesis in the fetal mouse ovary, but is simultaneously co-expressed within the same germ cells as Dazl

  10. Abnormal DNA methylation (显示 HELLS 抗体) of the DAZL promoter might represent an epigenetic marker of male infertility.

Zebrafish Deleted in Azoospermia-Like (DAZL) interaction partners

  1. Cortical depth and differential transport of vegetally localized dorsal and germ line determinants, Wnt8a (显示 WNT8A 抗体), grip2a, and Dazl, in the zebrafish embryo have been presented.

  2. that DAZL specifically binds the HuB 3'UTR (显示 UTS2R 抗体) and protects the message from degradation and/or enhances HuB translation, leading to the germ cell specific expression of HuB protein.

  3. DAZL relieves miRNA-mediated repression of germline mRNAs by controlling poly(A) tail length in zebrafish

  4. Data show that DAZ-like protein directly promotes the translation of the target mRNAs in vertebrates.

Cow (Bovine) Deleted in Azoospermia-Like (DAZL) interaction partners

  1. analysis of genomic structure and transcript variants of the bovine DAZL gene

Xenopus laevis Deleted in Azoospermia-Like (DAZL) interaction partners

  1. The dynamic intracellular localization suggests that Dazl is a multifunctional protein regulating RNA metabolism required for Xenopus germline development

  2. Daz- and pumilio-like genes are asymmetrically localized in Pelophylax (Rana) oocytes and are expressed during early spermatogenesis.

  3. Dazl has the ability to stimulate translation and function at the level of translation initiation.

Mouse (Murine) Deleted in Azoospermia-Like (DAZL) interaction partners

  1. The 3'-UTR (显示 UTS2R 抗体)-dependent suppression of DAZL in mouse follicular oocytes is required for the progression of normal pre-implantation development.

  2. Down-regulated expression of Sox9 (显示 SOX9 抗体) and Dazl may play important roles in MBP (显示 MBP 抗体)-induced testis injury.

  3. DAZL and CPEB1 (显示 CPEB1 抗体) regulate mRNA translation during oocyte maturation.

  4. findings demonstrate that DAZL associates with mRNA of Tet1 (显示 TET1 抗体), a catalyst of 5-hydroxylation of methyl-cytosine, and enhances Tet1 (显示 TET1 抗体) mRNA translation; DAZL enhances TET1 (显示 TET1 抗体)-mediated cytosine hydroxymethylation in embryonic stem cells that are actively reprogramming to a pluripotent ground state

  5. Both yeast and mouse contain an RNA-binding protein, Rim4 (显示 RIMS4 抗体) and DAZL, respectively, that functions in translation and forms SDS (显示 SDS 抗体)-resistant aggregates during gametogenesis.

  6. Our findings strengthen the importance of RA and Dazl in the meiotic transition, provide important details about the Stra8 (显示 STRA8 抗体) pathway, and open avenues to investigate early meiosis through analysis of Rec8 (显示 REC8 抗体) induction and function

  7. Data indicate that the germ cell-specific RNA binding protein DAZL limits both pluripotency and somatic differentiation in nascent primordial germ cells (PGCs).

  8. demonstrate that Boll (显示 BOLL 抗体) is also transiently expressed during oogenesis in the fetal mouse ovary, but is simultaneously co-expressed within the same germ cells as Dazl

  9. Studies indicate that in Dazl-Knockout mice, cord/tubule-like structures, OSE invaginations and clusters of steroidogenic cells became increasingly prominent with age, but these abnormal structures remained benign.

  10. alternative splicing of exon8 of mDazl leads to the generation of the novel splice variant, Dazl-Delta8.

Pig (Porcine) Deleted in Azoospermia-Like (DAZL) interaction partners

  1. cloning & characterization of the Deleted in AZoospermia Like (pDAZL) gene; pDAZL gene might be a good candidate gene of litter size trait & provides some marker information for marker-assisted selection.

  2. DNA methylation (显示 HELLS 抗体) may suppress DAZL expression in somatic cells by interfering with Sp1 (显示 SP1 抗体) binding.

  3. The porcine DAZL coding sequence is highly homologous to those reported for the human and mouse cDNAs, and DAZL expression increases during oocyte maturation.

  4. MK is able to maintain a proliferative PGC (显示 PGC 抗体) phenotype mediated by the suppression of DAZL in early germ cells

  5. DAZL enhances in vitro derived porcine germ cell formation and meiosis.

  6. DAZL c.570+385 A>G and DAZL c.735+150 C>A locus were the potential molecular markers for improving the sperm quality traits in pigs.

DAZL 抗原简介

蛋白简介

The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DAZL

  • deleted in azoospermia like (DAZL) 抗体
  • deleted in azoospermia-like (DAZL) 抗体
  • deleted in azoospermia-like (dazl) 抗体
  • deleted in azoospermia-like (Dazl) 抗体
  • deleted in azoospermia-like L homeolog (dazl.L) 抗体
  • deleted in azoospermia like (dazl) 抗体
  • deleted in azoospermia like (Dazl) 抗体
  • Daz-like 抗体
  • Dazh 抗体
  • DAZL 抗体
  • dazl-a 抗体
  • dazl-B 抗体
  • Dazl1 抗体
  • Dazla 抗体
  • spgyla 抗体
  • Tpx-2 抗体
  • Tpx2 抗体
  • Xdazl 抗体

Protein level used designations for DAZL

DAZ homolog , DAZ-like autosomal , SPGY-like-autosomal , deleted in azoospermia-like 1 , germline specific RNA binding protein , spermatogenesis gene on the Y-like autosomal , deleted in azoospermia-like , DAZ-like protein , deleted in azoospermia-like protein , deleted in azoospermia protein 3 , xtdazl , DAZ-like protein A , DAZ-like protein B , Deleted in azoospermia-like-B , deleted in azoospermia-like-A , xDazl-A , xDazl-B , Deleted in azoospermia-like 1

GENE ID SPECIES
1618 Homo sapiens
460209 Pan troglodytes
695763 Macaca mulatta
58039 Danio rerio
477055 Canis lupus familiaris
530116 Bos taurus
680486 Rattus norvegicus
394676 Xenopus (Silurana) tropicalis
374054 Gallus gallus
398041 Xenopus laevis
13164 Mus musculus
100410648 Callithrix jacchus
100453294 Pongo abelii
100484743 Ailuropoda melanoleuca
100542379 Meleagris gallopavo
100556590 Anolis carolinensis
100579498 Nomascus leucogenys
100625706 Sus scrofa
100722319 Cavia porcellus
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