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novel thyroid transcript negatively regulated by thyroid stimulating hormone [RGD, Feb 2006].. 再加上，我们可以发 和 和数多这个蛋白质的别的产品。
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Human Polyclonal DOCK9 Primary Antibody for ICC, IF - ABIN153062
Sakabe, Asai, Iijima, Maruyama: Age-related guanine nucleotide exchange factor, mouse Zizimin2, induces filopodia in bone marrow-derived dendritic cells. in Immunity & ageing : I & A 2012
Show all 2 Pubmed References
c.2262A>C substitution in DOCK9 leads to a splicing aberration. However, because the mutation effect was observed in vitro, a definitive relationship between DOCK9 and KTCN phenotype could not be established.
Studies indicate that that many of the mechanistic principles of the exchange process are conserved in the DOCK9-catalyzed reaction.
Sequence comparison combined with mutational analysis identified a new domain, which we named CZH2, that mediates direct interaction with Cdc42
DOCK9 contributes to both risk and increased illness severity in bipolar disorder.
novel functions for the N-terminal region of zizimin1.
DOCK2 and DOCK9 specifically recognize Rac2 and Cdc42 through their switch 1 as well as beta2-beta3 regions and the mode of recognition via switch 1 appears to be conserved among diverse Rac-specific DHR-2 GEFs
interaction between Smad2/3 and the Cdc42 guanine nucleotide exchange factor, Zizimin1, in response to TGF-beta1
through structural analysis of DOCK9-Cdc42 complexes, we identify a nucleotide sensor within the alpha10 helix of the DHR2 domain that contributes to release of guanine diphosphate (GDP) and then to discharge of the activated GTP-bound Cdc42
Thus, these results suggest that Zizimin1 plays an important role in dendrite growth in hippocampal neurons through activation of Cdc42.
novel thyroid transcript negatively regulated by thyroid stimulating hormone
dedicator of cytokinesis 9
, dedicator of cytokinesis protein 9
, Dedicator of cytokinesis protein 9
, dedicator of cytokinesis protein 9-like
, cdc42 guanine nucleotide exchange factor zizimin-1
, Thyroid regulating