Use your antibodies-online credentials, if available.
DEDD encodes a protein that contains a death effector domain (DED). 再加上，我们可以发DEDD 抗体 (55) 和 DEDD 蛋白 (8)和数多这个蛋白质的别的产品。
DEDD protein role in cell proliferation and migration of bladder cancer
Via direct interaction with the class III PI-3 (显示 PI3 ELISA试剂盒)-kinase (PI3KC3)/Beclin1 (显示 BECN1 ELISA试剂盒), DEDD activated autophagy and induced the degradation of Snail (显示 SNAI1 ELISA试剂盒) and Twist, two master regulators of EMT (显示 ITK ELISA试剂盒)
FAS (显示 FAS ELISA试剂盒)-associated death domain (FADD (显示 FADD ELISA试剂盒))-DED (显示 AATF ELISA试剂盒)-induced reactive oxygen species (ROS (显示 ROS1 ELISA试剂盒)) generation is triggered by membrane localization of FADD (显示 FADD ELISA试剂盒)-DED (显示 AATF ELISA试剂盒), which shifts the cells into a state that stimulates and fuels ROS (显示 ROS1 ELISA试剂盒) and ultimately results in cell death.
DEDD forms nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC
DEDD and DEDD2 (显示 DEDD2 ELISA试剂盒) may be important mediators for death receptors and that they may target caspases to the nucleus.
In uteri of Dedd-/- mice, development of the decidual zone and the surrounding edema after embryonic implantation was defective. This was accompanied by disintegration of implantation site structure, leading to embryonic death before placentation.
DEDD plays an important role in maintenance of the Akt (显示 AKT1 ELISA试剂盒) protein level, which in consequence supports the efficient incorporation of glucose into skeletal muscles and adipose tissues.
DEDD acts as a novel inhibitor of the mitotic Cdk1 (显示 CDK1 ELISA试剂盒)/cyclin B1 (显示 CCNB1 ELISA试剂盒) complex and is an impeder of cell mitosis, and its absence critically influences cell and body size via modulation of rRNA synthesis
The death effector domain-containing DEDD supports S6K1 (显示 RPS6KB1 ELISA试剂盒) activity via preventing Cdk1 (显示 CDK1 ELISA试剂盒)-dependent inhibitory phosphorylation.
This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
, death effector domain-containing protein
, death effector domain-containing testicular molecule
, tumor necrosis factor (ligand) superfamily, member 19