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DHX58 ELISA试剂盒

(DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))
Acts as a regulator of DDX58/RIG-I and IFIH1/MDA5 mediated antiviral signaling. Cannot initiate antiviral signaling as it lacks the CARD domain required for activating MAVS/IPS1- dependent signaling events. Can have both negative and positive regulatory functions related to DDX58/RIG-I and IFIH1/MDA5 signaling and this role in regulating signaling may be complex and could probably depend on characteristics of the infecting virus or target cells, or both. Its inhibitory action on DDX58/RIG-I DDX58/RIG-I for binding to the viral RNA, binding to DDX58/RIG-I and inhibiting its dimerization and interaction with MAVS/IPS1, competing with IKBKE in its binding to MAVS/IPS1 thereby inhibiting activation of interferon regulatory factor 3 (IRF3). Its positive regulatory role may involve unwinding or stripping nucleoproteins of viral RNA thereby facilitating their recognition by DDX58/RIG-I and IFIH1/MDA5. Involved in the innate immune response to various RNA viruses and some DNA viruses such as poxviruses, and also to the bacterial pathogen Listeria monocytogenes. Can bind both ssRNA and dsRNA, with a higher affinity for dsRNA. Shows a preference to 5'-triphosphorylated RNA, although it can recognize RNA lacking a 5'-triphosphate.
DHX58 ELISA 试剂盒 DHX58 ELISA 试剂盒 DHX58 ELISA 试剂盒 (ABIN3198476)

DHX58 适用: 人 Colorimetric Sandwich ELISA 15.63-1000 pg/mL Cell Culture Supernatant, Plasma, Serum

DHX58 ELISA 试剂盒 (ABIN1749851)

DHX58 适用: 山羊 Colorimetric Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate

DHX58 ELISA 试剂盒 (ABIN1748628)

DHX58 适用: 豚鼠 Colorimetric Competition ELISA 1.0-25 ng/mL Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate

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Popular DHX58 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN3198476
Quantity 96 tests
Datasheet Datasheet
Reactivity Goat
Analytical Method
Validations
Cat. No. ABIN1749851
Quantity 96 tests
Datasheet Datasheet
Reactivity Guinea Pig
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1748628
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774650
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1744964
Quantity 96 tests
Datasheet Datasheet
Reactivity Monkey
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1770978
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1743745
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1772202
Quantity 96 tests
Datasheet Datasheet
Reactivity Rabbit
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1747405
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1773426
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method
Validations
Cat. No. ABIN1751074
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1769754
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1746183
Quantity 96 tests
Datasheet Datasheet

Aliases for DHX58 ELISA试剂盒

DEXH-box helicase 58 L homeolog (dhx58.L) ELISA试剂盒
DExH-box helicase 58 (DHX58) ELISA试剂盒
DExH-box helicase 58 (dhx58) ELISA试剂盒
probable ATP-dependent RNA helicase DHX58 (LOC100566102) ELISA试剂盒
DEXH (Asp-Glu-X-His) box polypeptide 58 (dhx58) ELISA试剂盒
DEXH (Asp-Glu-X-His) box polypeptide 58 (Dhx58) ELISA试剂盒
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