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CDA encodes an enzyme involved in pyrimidine salvaging. 再加上，我们可以发CDA 蛋白 (47) 和 CDA 试剂盒 (14)和数多这个蛋白质的别的产品。
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Human Monoclonal CDA Primary Antibody for WB - ABIN1882220
Laliberté, Momparler: Human cytidine deaminase: purification of enzyme, cloning, and expression of its complementary DNA. in Cancer research 1994
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Human Monoclonal CDA Primary Antibody for WB - ABIN1882219
Demontis, Terao, Brivio, Zanotta, Bruschi, Garattini: Isolation and characterization of the gene coding for human cytidine deaminase. in Biochimica et biophysica acta 1999
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Human Polyclonal CDA Primary Antibody for IHC - ABIN965825
Gran, Bøyum, Johansen, Løvhaug, Seeberg: Growth inhibition of granulocyte-macrophage colony-forming cells by human cytidine deaminase requires the catalytic function of the protein. in Blood 1998
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results indicate that rs2072671 in CDA may be an important prognostic marker in NK-AML (显示 RUNX1 抗体) patients.
tumor cell lines that are susceptible to epigenetic nucleosides overexpress cytidine deaminase (CDA); CDA converts 5hmdC and 5fdC into variants of uridine that are incorporated into DNA, resulting in accumulation of DNA damage, and ultimately, cell death
RNA expression of deoxycytidine kinase (DCK (显示 DCK 抗体)), human equilibrative nucleoside transporter-1 (ENT1 (显示 SLC29A1 抗体)) and ribonucleotide reductase M1 (RRM1 (显示 RRM1 抗体)) were significantly higher and cytidine deaminase (CDA) was significantly lower in ex vivo Ara (显示 FOXC1 抗体)-C sensitive samples.
stimulation of PARP-1 (显示 PARP1 抗体) activity in CDA-deficient cells restores replication and, thus, chromosome segregation. Moreover, increasing intracellular dCTP levels generates under-replication-induced sister-chromatid bridges as efficiently as PARP-1 (显示 PARP1 抗体) knockdown
n the multivariate Cox (显示 COX8A 抗体) regression analysis, we found that age at diagnosis, wild-type genotype of the CDA A79C polymorphism, and wild-type genotype of the dCK (显示 DCK 抗体) C360G polymorphism were the most significant prognostic factors for predicting the risk of death
Single nucleotide polymorphisms in cytidine deaminase gene were associated with the efficacy of gemcitabine in Biliary Tract Cancer.
Polymorphisms in ABCB1 (显示 ABCB1 抗体), CDA, ENOSF1 (显示 ENOSF1 抗体),and TYMS (显示 TYMS 抗体) could help to predict specific and overall severe adverse reactions to capecitabine.
miR (显示 MLXIP 抗体)-484-modulated cytidine deaminase has a dual impact in promoting chemoresistance and suppressing cell proliferation in breast cancer
This case report calls for further prospective studies investigating the exact role that CDA status plays in the clinical outcome of patients treated with azacytidine.
The A79C CDA polymorphism did not show a significant impact on the response rate to gemcitabine in NSCLC patients, while the wild type CDA genotype was indeed correlated to a lower rate of incidence of severe anemia in patients taking gemcitabine.
Data indicate that a combination cytosine deaminase (CDA)/uracil phosphoribosyltransferase protein (UPRT (显示 UPRT 抗体))-expressing adipose tissue-derived mesenchymal stem cells (AT-MSCs) with lysomustine has a superior antitumor effect in the lung carcinoma model compared to monotherapies with transfected AT-MSCs or lysomustine alone.
Activation-induced cytidine deaminase (显示 AICDA 抗体) plays an important role in the containment of autoimmune diseases by negative regulation of autoreactive B cells.
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
, CytiDine Deaminase family member (cdd-1)
, CytiDine Deaminase family member (cdd-2)
, cytidine aminohydrolase
, cytosine nucleoside deaminase
, small cytidine deaminase