Complement Component (3b/4b) Receptor 1-Like 蛋白 (CR1L)

CR1L encodes a membrane-bound inhibitor of complement activation, which contains several tandemly arranged short consensus repeats (SCRs) of approximately 60 amino acids. 再加上,我们可以发Complement Component (3b/4b) Receptor 1-Like 抗体 (23)Complement Component (3b/4b) Receptor 1-Like 试剂盒 (6)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
大鼠 CR1L CR1L 54243 Q63135
CR1L 1379 Q2VPA4
CR1L 12946 Q64735
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Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
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CR1L 蛋白 by Origin and Source

Origin 在表达 标记
Human

Mouse (Murine)
,

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Human Complement Component (3b/4b) Receptor 1-Like (CR1L) interaction partners

  1. CR1L transcript appears to be limited to hematopoietic and fetal lymphoid tissue.

Mouse (Murine) Complement Component (3b/4b) Receptor 1-Like (CR1L) interaction partners

  1. Factor H (显示 CFH 蛋白) and Crry are critical for regulating complement activation at distinct anatomic sites within the kidney.

  2. this study has provided direct evidence for a role of Crry in controlling spontaneous alternative pathway complement activation on renal tubular epithelial cells.

  3. HBx can up-regulate CD59 (显示 CD59 蛋白) and Crry expression in podocytes through activating the P38 (显示 CRK 蛋白) pathway.

  4. Crry costimulation enhanced the in vitro expansion of natural Treg cells while maintaining their phenotypic and suppressive properties. Crry-expanded Treg cells decreasing antigen-dependent secretion of cytokines.

  5. Stmn2 (显示 STMN2 蛋白) and the chromosome 14 Rarb (显示 RARB 蛋白) region, but not Cr1 (显示 TDGF1 蛋白) or Clu (显示 CLU 蛋白) or Picalm (显示 PICALM 蛋白), have roles in prion (显示 PRNP 蛋白) disease.

  6. There is a significant reduction in the numbers of both neutrophils and macrophages in cardiac isografts isolated from mice treated with either complement receptor 2-Crry or CR2-factor H (显示 CFH 蛋白).

  7. Crry is clearly present in the placentas from spontaneous abortions in mice.

  8. Crry is the only membrane-bound complement regulator expressed on the basolateral surface of murine renal tubular epithelial cells under in vitro culture conditions.

  9. Data show that a single-nucleotide polymorphism in the first short consensus repeat of Sle1c Crry introduced a novel N-linked glycosylation site likely responsible for structural alteration.

  10. mesangial cell Crry limits complement activation and subsequent neutrophil recruitment in the setting of local immune complex deposition.

蛋白简介Complement Component (3b/4b) Receptor 1-Like (CR1L)

蛋白简介

This gene encodes a membrane-bound inhibitor of complement activation, which contains several tandemly arranged short consensus repeats (SCRs) of approximately 60 amino acids. The encoded protein may play a role in tumor immune surveillance, which is unrelated to complement inhibition. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with CR1L

  • complement C3b/C4b receptor 1 like (CR1L)
  • complement C3b/C4b receptor 1 like (Cr1l)
  • complement component (3b/4b) receptor 1-like (Cr1l)
  • Cr1 蛋白
  • CREG 蛋白
  • Crry 蛋白
  • Mcp 蛋白
  • mCRY 蛋白

Protein level used designations for CR1L

complement component (3b/4b) receptor 1-like , complement regulatory GPI-anchor protein , 5I2 antigen , Complement receptor related protein , antigen 5I2 , complement component receptor 1-like protein , complement receptor type 1 , complement regulatory protein Crry , complement C4b-binding protein CR-1-like protein , complement receptor related protein , protein p65

GENE ID SPECIES
419853 Gallus gallus
450119 Pan troglodytes
54243 Rattus norvegicus
1379 Homo sapiens
12946 Mus musculus
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