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C9ORF72 抗体

(Chromosome 9 Open Reading Frame 72 (C9ORF72))
Expansion of a hexanucleotide repeat in non-coding sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778, 21944779). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
C9ORF72 抗体  (AA 1-230) C9ORF72 抗体  (AA 1-230) C9ORF72 抗体 (AA 1-230) (ABIN7266391)

C9ORF72 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

C9ORF72 抗体  (AA 391-481) C9ORF72 抗体  (AA 391-481) C9ORF72 抗体 (AA 391-481) (ABIN1386141)

C9ORF72 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

C9ORF72 抗体  (AA 138-430) C9ORF72 抗体  (AA 138-430) C9ORF72 抗体 (AA 138-430) (ABIN7154647)

C9ORF72 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

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Popular C9ORF72 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN7266391
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
  • (3)
Cat. No. ABIN1386141
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7154647
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (2)
Cat. No. ABIN656852
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1327557
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3028570
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1399939
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN1399935
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN1399936
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN1399937
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN1399938
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN1399940
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN4998829
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN4998830
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN1417806
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our C9ORF72 抗体

Conlon, Fagegaltier, Agius, Davis-Porada, Gregory, Hubbard, Kang, Kim, Phatnani, Kwan, Sareen, Broach, Simmons, Arcila-Londono, Lee, Van Deerlin, Shneider, Fraenkel, Ostrow, Baas, Zaitlen, Berry et al.: "Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism. ..." in: eLife, Vol. 7, (2019) (PubMed).

Davidson, Robinson, Rollinson, Pickering-Brown, Xiao, Robertson, Mann: "Immunohistochemical detection of C9orf72 protein in frontotemporal lobar degeneration and motor neurone disease: patterns of immunostaining and an evaluation of commercial antibodies." in: Amyotrophic lateral sclerosis & frontotemporal degeneration, Vol. 19, Issue 1-2, pp. 102-111, (2018) (PubMed).

Sullivan, Zhou, Robins, Paushter, Kim, Smolka, Hu: "The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway." in: Acta neuropathologica communications, Vol. 4, Issue 1, pp. 51, (2017) (PubMed).

Burberry, Suzuki, Wang, Moccia, Mordes, Stewart, Suzuki-Uematsu, Ghosh, Singh, Merkle, Koszka, Li, Zon, Rossi, Trowbridge, Notarangelo, Eggan: "Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease." in: Science translational medicine, Vol. 8, Issue 347, pp. 347ra93, (2017) (PubMed).

Wen, Tan, Westergard, Krishnamurthy, Markandaiah, Shi, Lin, Shneider, Monaghan, Pandey, Pasinelli, Ichida, Trotti: "Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death." in: Neuron, Vol. 84, Issue 6, pp. 1213-25, (2014) (PubMed).

Snowden, Rollinson, Thompson, Harris, Stopford, Richardson, Jones, Gerhard, Davidson, Robinson, Gibbons, Hu, DuPlessis, Neary, Mann, Pickering-Brown: "Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations." in: Brain : a journal of neurology, Vol. 135, Issue Pt 3, pp. 693-708, (2012) (PubMed).

Satoh, Tabunoki, Ishida, Saito, Arima: "Dystrophic neurites express C9orf72 in Alzheimer's disease brains." in: Alzheimer's research & therapy, Vol. 4, Issue 4, pp. 33, (2012) (PubMed).

Brettschneider, Van Deerlin, Robinson, Kwong, Lee, Ali, Safren, Monteiro, Toledo, Elman, McCluskey, Irwin, Grossman, Molina-Porcel, Lee, Trojanowski: "Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion." in: Acta neuropathologica, Vol. 123, Issue 6, pp. 825-39, (2012) (PubMed).

Aliases for C9ORF72 抗体

chromosome Z C9orf72 homolog (CZH9orf72) 抗体
chromosome 9 open reading frame 72 (C9orf72) 抗体
RIKEN cDNA 3110043O21 gene (3110043O21Rik) 抗体
similar to RIKEN cDNA 3110043O21 (RGD1359108) 抗体
chromosome 9 open reading frame 72 L homeolog (c9orf72.L) 抗体
AI840585 抗体
ALSFTD 抗体
c9orf72 抗体
CZH9orf72 抗体
FTDALS 抗体
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