Chromosome 6 Open Reading Frame 25 蛋白 (C6orf25)

C6orf25 is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. 再加上,我们可以发C6orf25 抗体 (30)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
大鼠 C6orf25 C6orf25 406865 Q6MG59
C6orf25 80739 O95866
小鼠 C6orf25 C6orf25 106722  
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人细胞 His tag 50 μg Log in to see 20至21个工作日
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C6orf25 蛋白 by Origin and Source

Origin 在表达 标记
Human ,
, ,

更多Chromosome 6 Open Reading Frame 25 (C6orf25)互动伙伴

Human Chromosome 6 Open Reading Frame 25 (C6orf25) interaction partners

  1. G6B seems to act through an autosomal recessive mode of disease transmission in this family and regarded as the gene responsible for the observed hematological disorder.

  2. Heparin might modulate the interaction of G6b with its as yet unidentified protein ligand

  3. G6B represents a novel inhibitory receptor found on the surface of platelets

  4. G6b-B expression is highly restricted to peripheral CD4 (显示 CD4 蛋白)+ T cells and up-regulated by the IL-4 (显示 IL4 蛋白)-induced STAT6 (显示 STAT6 蛋白) pathway, suggesting that G6b-B is involved in regulation of the immune response by CD4 (显示 CD4 蛋白)+ T cell-mediated and IL-4 (显示 IL4 蛋白) induced regulatory mechanisms.

  5. G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2 (显示 CLEC1B 蛋白).

Mouse (Murine) Chromosome 6 Open Reading Frame 25 (C6orf25) interaction partners

  1. these findings establish G6b-B as a major inhibitory receptor regulating megakaryocyte activation, function, and platelet production.

蛋白简介C6orf25

蛋白简介

This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with C6orf25

  • megakaryocyte and platelet inhibitory receptor G6b (Mpig6b)
  • megakaryocyte and platelet inhibitory receptor G6b (MPIG6B)
  • C6orf25 蛋白
  • G6B 蛋白
  • LOC745085 蛋白
  • NG31 蛋白

Protein level used designations for C6orf25

protein G6b , immunoglobulin receptor , G6B protein , G6b protein , ITIM-receptor G6b-B

GENE ID SPECIES
406865 Rattus norvegicus
80739 Homo sapiens
745085 Pan troglodytes
106722 Mus musculus
617577 Bos taurus
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