Chromosome 10 Open Reading Frame 2 蛋白 (C10ORF2)

C10ORF2 encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. 再加上,我们可以发Chromosome 10 Open Reading Frame 2 抗体 (56)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
C10ORF2 56652 Q96RR1
大鼠 C10ORF2 C10ORF2 309441  
C10ORF2 226153 Q8CIW5
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
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C10ORF2 蛋白 by Origin and Source

Origin 在表达 标记
Human , , ,
, ,
Mouse (Murine)

更多Chromosome 10 Open Reading Frame 2 (C10ORF2)互动伙伴

Human Chromosome 10 Open Reading Frame 2 (C10ORF2) interaction partners

Mouse (Murine) Chromosome 10 Open Reading Frame 2 (C10ORF2) interaction partners

蛋白简介Chromosome 10 Open Reading Frame 2 (C10ORF2)

蛋白简介

This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with C10ORF2

  • twinkle mtDNA helicase L homeolog (twnk.L)
  • twinkle mtDNA helicase (TWNK)
  • twinkle mtDNA helicase (Twnk)
  • ATXN8 蛋白
  • C6H10orf2 蛋白
  • D19Ertd626e 蛋白
  • IOSCA 蛋白
  • MTDPS7 蛋白
  • PEO 蛋白
  • PEO1 蛋白
  • PEOA3 蛋白
  • SANDO 蛋白
  • SCA8 蛋白
  • Twinl 蛋白

Protein level used designations for C10ORF2

uncharacterized protein LOC414487 , twinkle protein, mitochondrial , T7 gp4-like protein with intramitochondrial nucleoid localization , T7 helicase-related protein with intramitochondrial nucleoid localization , T7-like mitochondrial DNA helicase , ataxin 8 , mitochondrial twinkle protein , progressive external ophthalmoplegia 1 protein , progressive external ophthalmoplegia 1 , progressive external ophthalmoplegia 1 homolog , progressive external ophthalmoplegia 1 protein homolog

GENE ID SPECIES
414487 Xenopus laevis
710958 Macaca mulatta
56652 Homo sapiens
486845 Canis lupus familiaris
309441 Rattus norvegicus
425626 Gallus gallus
226153 Mus musculus
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