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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体

(Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB))
E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-cell receptor), BCR (B- cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways. In naive T-cells, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production. Also acts by promoting PIK3R1/p85 ubiquitination, which impairs its recruitment to the TCR and subsequent activation. In activated T- cells, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy. In B-cells, acts by ubiquitinating SYK and promoting its proteasomal degradation. Slightly promotes SRC ubiquitination. May be involved in EGFR ubiquitination and internalization. May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3. {ECO:0000269|PubMed:10646608, ECO:0000269|PubMed:10646609, ECO:0000269|PubMed:11070165, ECO:0000269|PubMed:11526404, ECO:0000269|PubMed:12771181, ECO:0000269|PubMed:15308098}.
Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 (ABIN760256)

CBLB 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (N-Term) 抗体 Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (N-Term) 抗体 Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (N-Term) 抗体 (ABIN6260515)

CBLB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 适用

Find Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 for a variety of species such as anti-Human Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase, anti-Mouse Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase, anti-Rat Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase. The species listed below are among those available. Click on a link to go to the corresponding products.

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 应用范围

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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 抗体来源

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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 抗原表位

Find Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 克隆形成能力

Find available monoclonal or polyclonal Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体. Click on a link to go to the corresponding products.

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 克隆

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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 标记

Find Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN760256
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN6260515
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN3015830
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC (p), FACS
Validations
  • (3)
Cat. No. ABIN652612
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, FACS
Validations
  • (3)
Cat. No. ABIN3003861
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2855378
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN760258
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN913846
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN913845
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN913847
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN2806042
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN913848
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN5009982
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN5009981
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN760261
Quantity 100 μL
Datasheet Datasheet

Aliases for Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体

Cbl proto-oncogene B, E3 ubiquitin protein ligase S homeolog (cblb.S) 抗体
Cbl proto-oncogene B, E3 ubiquitin protein ligase L homeolog (cblb.L) 抗体
Casitas B-lineage lymphoma b (Cblb) 抗体
Cbl proto-oncogene B (Cblb) 抗体
Cbl proto-oncogene B (CBLB) 抗体
AI429560 抗体
AI851073 抗体
Cbl-b 抗体
cblb 抗体
rnf56 抗体
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