anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) 抗体

Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. 再加上,我们可以发Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase 试剂盒 (10)Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CILP 8483 O75339
CILP 214425 Q66K08
CILP 315761  
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Showing 10 out of 46 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
大鼠 山羊 非结合性 ELISA, WB ABIN185679 (0.03µg/ml) staining of rat spinal cord lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6至7个工作日
$358.02
详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
$289.00
详细
山羊 非结合性 ELISA, WB 100 μg Log in to see 7至9个工作日
$610.50
详细
山羊 非结合性 EIA, WB   0.1 mg Log in to see 8至11个工作日
$462.00
详细
非结合性 WB MCF-7 lysate probed with Rabbit Anti-CILP Polyclonal Antibody, Unconjugated  at 1:5000 for 90min at 37˚C. 100 μL Log in to see 3至7个工作日
$306.90
详细
小鼠 非结合性 ELISA Detection limit for recombinant GST tagged CILP is approximately 0.1ng/ml as a capture antibody. 100 μg Log in to see 8至11个工作日
$461.00
详细
大鼠 山羊 非结合性 IHC (p), ELISA, WB ABIN251581(0.03ug/ml) staining of Rat Spinal Cord lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Immunohistochemistry-Paraffin: CILP-1 Antibody [ABIN2515816] - CILP using ABIN2515816 in Rat Spinal Cord lysate (35ug protein in RIPA buffer) at 0.03ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$485.88
详细
非结合性 ICC, IHC, WB DAB staining on IHC-P; Samples: Human Liver cancer Tissue 100 μg Log in to see 13至16个工作日
$350.00
详细
小鼠 非结合性 ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Brain tissue 100 μg Log in to see 13至16个工作日
$360.00
详细
HRP WB   100 μL Log in to see 14至21个工作日
$405.90
详细

引用最多的anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase 抗体

  1. Rat (Rattus) Polyclonal CILP Primary Antibody for IHC (p), ELISA - ABIN251581 : Seki, Kawaguchi, Chiba, Mikami, Kizawa, Oya, Mio, Mori, Miyamoto, Masuda, Tsunoda, Kamata, Kubo, Toyama, Kimura, Nakamura, Ikegawa: A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease. in Nature genetics 2005 (PubMed)

更多抗Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase的相互作用对抗体

Human Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) interaction partners

  1. CILP rs2073711 TT is associated with increased risk of symmetrical hand osteoarthritis particularly in individuals with low variation in work tasks.

  2. Meta-analysis. Our results confirm the positive association between CILP and intervertebral disc degeneration, providing novel clues for clarifying the role of CILP in the development of IVD (显示 IVD 抗体).

  3. CILP is involved in the etiology of intervertebral disc degeneration among young adults.

  4. The researchers found that the single nucleotide polymorphism (1184T/C) of the CILP gene is associated an increased risk of lumbar disc degeneration in male athletes.

  5. CILP regulates TGF-beta (显示 TGFB1 抗体) signaling and that this regulation has a crucial role in the etiology and pathogenesis of LDD.

  6. These observations, together with the finding that CILP protein binds and inhibits TGF-beta1 (显示 TGFB1 抗体), suggest that CILP and TGF-beta1 (显示 TGFB1 抗体) may form a functional feedback loop that controls chondrocyte metabolism.

  7. SNP analysis suggested that the CILP gene is not a major risk factor for symptoms of lumbar disc disease in Finnish or Chinese populations.

  8. the CILP gene 1184T/C polymorphism is a significant risk factor for lumbar disc degeneration occurrence in Japanese collegiate judo athletes

Mouse (Murine) Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) interaction partners

  1. Overexpression of CILP in the nucleus pulposus cells promotes disc degeneration, indicating that CILP plays a direct role in the pathogenesis of lumbar disc disease.

Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) 抗原简介

蛋白简介

Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins\; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.

Gene names and symbols associated with CILP

  • cartilage intermediate layer protein (CILP) 抗体
  • cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (Cilp) 抗体
  • cartilage intermediate layer protein (Cilp) 抗体
  • cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (cilp) 抗体
  • cartilage intermediate layer protein 1 (LOC100336614) 抗体
  • 9830114D16 抗体
  • C130036G17Rik 抗体
  • CILP 抗体
  • CILP-1 抗体
  • HsT18872 抗体
  • im:7137994 抗体
  • NTPPH 抗体

Protein level used designations for CILP

cartilage intermediate layer protein 1 , cartilage intermediate layer protein 1 C1 , cartilage intermediate layer protein 1 C2 , cartilage intermediate-layer protein , CILP-1 , nucleotide pyrophosphohydrolase , cartilage intermediate layer protein, nucleotide pyrophosphohydrolase , cartilage intermediate layer protein 1-like , CILP protein

GENE ID SPECIES
8483 Homo sapiens
214425 Mus musculus
315761 Rattus norvegicus
397672 Sus scrofa
415533 Gallus gallus
453514 Pan troglodytes
487603 Canis lupus familiaris
100224477 Taeniopygia guttata
100390902 Callithrix jacchus
100475451 Ailuropoda melanoleuca
100541878 Meleagris gallopavo
100586830 Nomascus leucogenys
553329 Danio rerio
100336614 Bos taurus
100053337 Equus caballus
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