Carboxypeptidase M 蛋白 (CPM)

The protein encoded by CPM is a membrane-bound arginine/lysine carboxypeptidase. 再加上,我们可以发Carboxypeptidase M 抗体 (77)Carboxypeptidase M 试剂盒 (14)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
CPM 70574 Q80V42
大鼠 CPM CPM 314855  
CPM 1368 P14384
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Showing 10 out of 15 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
详细
Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
详细
人细胞 His tag 10 μg Log in to see 20至21个工作日
$250.80
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人细胞 小鼠 His tag 100 μg Log in to see 20至21个工作日
$437.80
详细
人细胞 His tag   50 μg Log in to see 4 Days
$522.50
详细
HEK-293 Cells His tag Human Carboxypeptidase M, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%. 50 μg Log in to see 11 Days
$346.50
详细
人细胞 小鼠 His tag   50 μg Log in to see 4 Days
$177.10
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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人细胞 His tag   10 μg Log in to see 15至16个工作日
$300.00
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酵母菌 Orang-Utan His tag   1 mg Log in to see 60至71个工作日
$3,125.83
详细

CPM 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine) ,

Human , , , ,
,

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Mouse (Murine) Carboxypeptidase M (CPM) interaction partners

  1. spatial proximity between angiotensin-converting enzyme (显示 ACE 蛋白) and the endogenous CPM enables an angiotensin-converting enzyme (显示 ACE 蛋白) evoked release of CPM

  2. of the 33 transcripts from the CPM locus, four were evaluated with one showing expression patterns that differed considerably from the other ones and from the mouse CPM gene, suggesting that there may be more than one transcriptional unit in this locus

Human Carboxypeptidase M (CPM) interaction partners

  1. Low CPM expression is associated with colorectal cancer.

  2. CPM binding to extracellular loop 2 of the B1R (显示 BDKRB1 蛋白) results in positive allosteric modulation of B1R (显示 BDKRB1 蛋白) signaling, and disruption of this interaction could provide a novel therapeutic approach to reduce pathological B1R (显示 BDKRB1 蛋白) signaling.

  3. Carboxypeptidase M expression is lost in human renal cell carcinoma (显示 MOK 蛋白) tumor cells, whereas it is abundant in tumor-associated foam cells and neovasculature.

  4. CPM and B1Rs on cell membranes form a critical complex that potentiates B1R (显示 BDKRB1 蛋白) signaling.

  5. CPM amplification could be used as an alternative diagnostic tool for the diagnosis of well-differentiated liposarcoma/atypical lipomatous tumors.

  6. Results report the crystallization of human carboxypeptidase M and its 3.0 angstrom crystal structure.

  7. Carboxypeptidase M and kinin B1 (显示 BDKRB1 蛋白) receptors interact to facilitate efficient b1 signaling from B2 agonists

  8. Cleavage of the C-terminal lysine residue of SDF-1alpha by CPM leads to attenuated chemotactic responses.

  9. CPM is membrane-bound via attachment of glycosylphosphatidylinositol at Ser406. Glu264 is a critical catalytic residue, whereas Glu260 affects stability and substrate kinetics.

蛋白简介Carboxypeptidase M (CPM)

蛋白简介

The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.

Gene names and symbols associated with Carboxypeptidase M 蛋白 (CPM)

  • carboxypeptidase M (CPM)
  • carboxypeptidase M (cpm)
  • carboxypeptidase D (LOC5574253)
  • carboxypeptidase M (Cpm)
  • 1110060I01Rik 蛋白
  • 5730456K23Rik 蛋白
  • AA589379 蛋白
  • CPM 蛋白
  • E030045M14Rik 蛋白
  • im:7143022 蛋白
  • im:7143022l 蛋白
  • si:dkey-11p6.1 蛋白
  • zgc:110307 蛋白

Protein level used designations for Carboxypeptidase M 蛋白 (CPM)

carboxypeptidase M , carboxypeptidase m , renal carboxypeptidase , urinary carboxypeptidase B , carboxypeptidase D

GENE ID SPECIES
417843 Gallus gallus
550253 Danio rerio
718315 Macaca mulatta
5574253 Aedes aegypti
70574 Mus musculus
314855 Rattus norvegicus
1368 Homo sapiens
452067 Pan troglodytes
513281 Bos taurus
100349485 Oryctolagus cuniculus
100171502 Pongo abelii
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