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The protein encoded by CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. 再加上，我们可以发CD63 抗体 (673) 和 CD63 蛋白 (22)和数多这个蛋白质的别的产品。
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In renal proximal tubules, CD63 determines the insertion of OCT2 (显示 SLC22A2 ELISA试剂盒) into the proper membrane domain and mediates transporter regulation by trafficking processes.
TIMP1 (显示 TIMP1 ELISA试剂盒) signaling via CD63 leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.
The Muted protein is important for the steady-state level of CD63.
Data show that CD63 is a crucial player in the regulation of the tumor cell-intrinsic metastatic potential by affecting cell plasticity.
These findings identify CD63 as an important component of allergic inflammation.
CD63 serves to bridge between beta1 integrin and VEGFR2 (显示 KDR ELISA试剂盒) because CD63 silencing disrupted VEGFR2 (显示 KDR ELISA试剂盒)-beta1 integrin complex formation identified using proximity ligation assay
Loss of CD63 is associated impairment of amyloidogenesis and downstream melanosome morphogenesis.
Loss of CD63 has a similar phenotype to loss of P-selectin (显示 SELP ELISA试剂盒) itself, thus CD63 is an essential cofactor to P-selectin (显示 SELP ELISA试剂盒).
CXCR4 (显示 CXCR4 ELISA试剂盒) can be downregulated on activated B cells by IL-21 (显示 IL21 ELISA试剂盒)-induced endocytosis and CD63-mediated endosomal recruitment.
The findings identify palmitoylation-dependent association with the tetraspanin CD63 as the mechanism by which Syt VII (显示 SYT7 ELISA试剂盒) is targeted to lysosomes.
our results identify the CD63-syntenin-1 (显示 SDCBP ELISA试剂盒)-ALIX (显示 PDCD6IP ELISA试剂盒) complex as a key regulatory component in post-endocytic HPV trafficking.
Exosomal markers CD63 and CD9 (显示 CD9 ELISA试剂盒) are elevated in pancreatic tumor tissues.
CD63 and exosome expression is altered in scleroderma dermal fibroblasts
CD63 is a critical player in LMP1 (显示 PDLIM7 ELISA试剂盒) exosomal trafficking and LMP1 (显示 PDLIM7 ELISA试剂盒)-mediated enhancement of exosome production and may play further roles in limiting downstream LMP1 (显示 PDLIM7 ELISA试剂盒) signaling.
Concentrations of Cd63 were elevated in gingival crevicular fluid of patients with pre-eclampsia.
CD163 (显示 CD163 ELISA试剂盒)(+) TAMs in oral premalignant lesions coexpress CD163 (显示 CD163 ELISA试剂盒) and STAT1 (显示 STAT1 ELISA试剂盒), suggesting that the TAMs in oral premalignant lesions possess an M1 phenotype in a Th1 (显示 TH1L ELISA试剂盒)-dominated micromilieu.
Our findings reveal that elevated levels of TIMP-1 (显示 TIMP1 ELISA试剂盒) impact on neutrophil homeostasis via signaling through CD63.
These findings indicate that rhTIMP-1 promotes clonogenic expansion and survival in human progenitors via the activation of the CD63/PI3K (显示 PIK3CA ELISA试剂盒)/pAkt (显示 AKT1 ELISA试剂盒) signaling pathway
It was shown that treatment of macrophages with anti-CD63 inhibits CCR5-mediated virus infection in a cell type-specific manner, but that no inhibition of CXCR4 (显示 CXCR4 ELISA试剂盒)-tropic viruses occurs.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
melanoma 1 antigen
, CD63 antigen
, CD63 antigen (melanoma 1 antigen)
, lysosomal-associated membrane protein 3
, lysosome-associated membrane glycoprotein 3
, melanoma-associated antigen ME491
, melanoma-associated antigen MLA1
, ocular melanoma-associated antigen
, ME491/CD63 antigen
, mast cell antigen AD1